Hub : Traits : Soleus weight : ← →

chr8:102,533,918-104,393,934

Trait: Soleus weight

Best TWAS P=1.391944e-07 · Best GWAS P=4.147343e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Cep63	intron excision ratio	chr8:103163124:103164803	0.06	0.01	lasso	1	0.01	2.2e-02	5.2	-5.2	2.2e-07	-0.77	0.27	0.41	FALSE
2	BLA	Rab6b	mRNA stability	ENSRNOG00000009198	0.07	0.04	top1	1	0.04	3.6e-03	5.1	-5.1	3.1e-07	-0.56	0.08	0.09	FALSE
3	Brain	Amotl2	gene expression	ENSRNOG00000008487	0.13	0.09	blup	1756	0.11	3.0e-10	5.1	5.1	3.3e-07	0.90	0.32	0.69	FALSE
4	LHb	Cep63	alternative polyA	ENSRNOT00000031313	0.30	0.10	top1	1	0.10	2.4e-03	5.2	5.2	2.5e-07	0.94	0.09	0.06	FALSE
5	LHb	Cep63	alternative polyA	ENSRNOT00000031313	0.30	0.13	top1	1	0.13	6.3e-04	5.2	5.2	2.5e-07	0.94	0.09	0.07	FALSE
6	LHb	Cep63	alternative polyA	ENSRNOT00000084413	0.31	0.10	top1	1	0.10	1.9e-03	5.2	-5.2	2.5e-07	-0.95	0.09	0.06	FALSE
7	LHb	Amotl2	gene expression	ENSRNOG00000008487	0.39	0.19	lasso	4	0.21	9.3e-06	5.1	5.2	1.7e-07	0.96	0.28	0.72	FALSE
8	Liver	Slco2a1	intron excision ratio	chr8:103637317:103654517	0.09	0.04	top1	1	0.04	1.2e-05	5.2	-5.2	2.2e-07	-0.70	0.10	0.52	FALSE
9	Liver	Slco2a1	intron excision ratio	chr8:103641675:103654517	0.08	0.03	top1	1	0.03	7.2e-04	5.2	5.2	2.2e-07	0.81	0.05	0.07	FALSE
10	Liver	NA	intron excision ratio	chr8:103586326:103587645	0.06	0.00	enet	41	0.01	2.2e-02	5.1	5.1	3.5e-07	0.92	0.17	0.58	FALSE
11	NAcc	Cep63	intron excision ratio	chr8:103165082:103165787	0.06	0.02	blup	1719	0.02	1.4e-02	5.1	5.3	1.4e-07	0.93	0.24	0.53	TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.