Hub : Traits : Soleus weight : ← : →

chr2:113,625,967-117,667,018

Trait: Soleus weight

Best TWAS P=8.08e-10 · Best GWAS P=7.39e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Gnb4	alternative polyA	NM_001013910.2	0.09	1693	0.09	5.7e-10	-5.62	1.92e-08	0.52	FALSE
Adipose	Gnb4	alternative polyA	XM_039101981.1	0.09	1693	0.09	8.6e-10	5.62	1.96e-08	0.52	FALSE
Adipose	Gnb4	alternative TSS	XM_039101981.1	0.03	1	0.03	6.7e-04	-5.74	9.66e-09	0.03	FALSE
Adipose	Gnb4	alternative TSS	XM_039101981.1	0.05	1693	0.04	9.2e-06	5.73	9.94e-09	0.51	FALSE
Adipose	Gnb4	alternative TSS	XM_039101982.1	0.05	1693	0.04	8.4e-06	-5.74	9.41e-09	0.51	FALSE
Adipose	Dnajc19	gene expression	Dnajc19	0.03	2267	0.01	7.4e-02	5.37	7.98e-08	0.48	FALSE
Adipose	Gnb4	gene expression	Gnb4	0.38	31	0.29	1.7e-32	-5.78	7.27e-09	0.53	FALSE
Adipose	Mfn1	gene expression	Mfn1	0.16	1	0.18	4.6e-19	5.98	2.18e-09	0.77	FALSE
Adipose	Gnb4	isoform ratio	NM_001013910.2	0.09	14	0.09	2.4e-10	-5.85	5.06e-09	0.53	FALSE
Adipose	Gnb4	isoform ratio	XM_039101981.1	0.04	1693	0.04	5.2e-05	5.86	4.50e-09	0.51	FALSE
Adipose	Mrpl47	isoform ratio	XM_039101984.1	0.02	1703	0.01	1.0e-02	-5.5	3.80e-08	0.37	FALSE
Adipose	Gnb4	intron excision ratio	chr2_115386834_115389328	0.03	1	0.02	4.3e-03	-5.74	9.66e-09	0.03	FALSE
Adipose	Gnb4	intron excision ratio	chr2_115386834_115400546	0.03	1	0.02	3.3e-03	5.74	9.66e-09	0.03	FALSE
Adipose	Dnajc19	mRNA stability	Dnajc19	0.03	2267	0.02	3.9e-03	5.85	4.91e-09	0.54	FALSE
Adipose	Gnb4	mRNA stability	Gnb4	0.13	1	0.12	1.2e-13	5.75	8.69e-09	0.41	FALSE
Adipose	Mfn1	mRNA stability	Mfn1	0.06	1	0.05	1.4e-06	5.98	2.18e-09	0.66	FALSE
Adipose	Pik3ca	mRNA stability	Pik3ca	0.07	1	0.05	1.2e-06	5.82	5.97e-09	0.51	FALSE
BLA	Gnb4	alternative polyA	NM_001013910.2	0.17	1694	0.23	1.7e-12	-5.51	3.58e-08	0.51	FALSE
BLA	Gnb4	alternative polyA	XM_039101981.1	0.18	1694	0.23	1.0e-12	5.54	3.09e-08	0.52	FALSE
BLA	Mfn1	gene expression	Mfn1	0.11	5	0.08	4.9e-05	-5.41	6.18e-08	0.44	FALSE
BLA	Ndufb5	gene expression	Ndufb5	0.19	1702	0.09	1.5e-05	5.97	2.37e-09	0.48	FALSE
BLA	Usp13	gene expression	Usp13	0.05	1753	0.01	5.7e-02	5.2	2.01e-07	0.29	FALSE
BLA	Zmat3	gene expression	Zmat3	0.16	41	0.15	1.6e-08	-5.77	7.85e-09	0.51	FALSE
BLA	Gnb4	isoform ratio	NM_001013910.2	0.19	22	0.23	2.0e-12	-5.75	8.69e-09	0.52	FALSE
BLA	Gnb4	isoform ratio	XM_039101981.1	0.09	1694	0.06	3.1e-04	5.85	5.01e-09	0.5	FALSE
BLA	Gnb4	isoform ratio	XR_005500258.1	0.21	192	0.12	7.2e-07	-5.56	2.72e-08	0.52	FALSE
BLA	LOC103691527	isoform ratio	XR_005500860.1	0.06	1	0.04	3.6e-03	5.97	2.33e-09	0.04	FALSE
BLA	Gnb4	intron excision ratio	chr2_115389413_115400546	0.06	1694	0.04	2.0e-03	5.72	1.05e-08	0.46	FALSE
BLA	Ccdc39	mRNA stability	Ccdc39	0.46	197	0.44	1.4e-25	5.42	6.05e-08	0.51	FALSE
BLA	Mfn1	mRNA stability	Mfn1	0.09	1	0.09	2.7e-05	-5.74	9.39e-09	0.11	FALSE
BLA	Pex5l	mRNA stability	Pex5l	0.07	61	0.07	1.6e-04	-5.99	2.06e-09	0.42	FALSE
Brain	Gnb4	alternative polyA	NM_001013910.2	0.22	1694	0.15	1.4e-13	-5.98	2.20e-09	0.52	FALSE
Brain	Gnb4	alternative polyA	XM_039101981.1	0.23	1694	0.15	1.2e-13	5.98	2.27e-09	0.52	FALSE
Brain	Ttc14	alternative TSS	NM_001107666.2	0.14	1	0.1	1.5e-09	5.97	2.31e-09	0.46	FALSE
Brain	Ttc14	alternative TSS	XM_017590853.2	0.14	1	0.1	1.0e-09	-5.97	2.31e-09	0.46	FALSE
Brain	Ttc14	alternative TSS	NM_001107666.2	0.13	1	0.1	3.4e-09	5.97	2.31e-09	0.46	FALSE
Brain	Ttc14	alternative TSS	XM_039102238.1	0.13	1	0.1	1.3e-09	-5.97	2.31e-09	0.46	FALSE
Brain	LOC103691527	gene expression	LOC103691527	0.1	2107	0.08	5.7e-08	5.65	1.65e-08	0.65	FALSE
Brain	Mfn1	gene expression	Mfn1	0.25	24	0.3	1.0e-28	-6.01	1.83e-09	0.54	FALSE
Brain	Pex5l	gene expression	Pex5l	0.06	1	0.09	2.5e-08	5.51	3.66e-08	0.05	FALSE
Brain	Gnb4	isoform ratio	NM_001013910.2	0.15	1694	0.13	8.3e-12	-5.98	2.26e-09	0.51	FALSE
Brain	Gnb4	intron excision ratio	chr2_115386834_115389328	0.09	113	0.08	3.5e-08	-5.22	1.75e-07	0.56	FALSE
Brain	Gnb4	intron excision ratio	chr2_115386834_115400546	0.12	1	0.13	5.6e-12	5.74	9.56e-09	0.39	FALSE
Brain	Gnb4	intron excision ratio	chr2_115389413_115400546	0.03	1694	0.02	3.5e-03	5.43	5.76e-08	0.44	FALSE
Brain	Fxr1	mRNA stability	Fxr1	0.14	26	0.12	4.4e-11	5.8	6.47e-09	0.44	FALSE
Brain	Gnb4	mRNA stability	Gnb4	0.07	1	0.07	4.4e-07	5.85	5.03e-09	0.48	FALSE
Brain	Kcnmb2	mRNA stability	Kcnmb2	0.05	2146	0.02	5.9e-03	-5.2	1.99e-07	0.44	FALSE
Brain	Mfn1	mRNA stability	Mfn1	0.03	1785	0.02	1.1e-02	5.39	6.88e-08	0.39	FALSE
Brain	Pik3ca	mRNA stability	Pik3ca	0.16	1936	0.16	4.4e-15	-5.54	3.06e-08	0.46	FALSE
Eye	LOC103691527	gene expression	LOC103691527	0.36	1	0.18	9.4e-04	-5.47	4.46e-08	0.06	FALSE
Eye	Usp13	gene expression	Usp13	0.4	1753	0.25	1.1e-04	5.6	2.11e-08	0.42	FALSE
IL	Gnb4	gene expression	Gnb4	0.29	1694	0.24	1.6e-06	5.48	4.31e-08	0.49	FALSE
IL	Mfn1	gene expression	Mfn1	0.15	1	0.13	4.1e-04	5.96	2.53e-09	0.07	FALSE
IL	Ccdc39	mRNA stability	Ccdc39	0.38	2508	0.23	2.9e-06	-5.82	6.06e-09	0.52	FALSE
IL	Pik3ca	mRNA stability	Pik3ca	0.29	18	0.23	3.9e-06	-5.98	2.25e-09	0.47	FALSE
LHb	Zmat3	gene expression	Zmat3	0.15	1	0	3.1e-01	5.73	1.02e-08	0.06	FALSE
LHb	Pik3ca	mRNA stability	Pik3ca	0.16	1936	0.19	2.9e-05	-5.93	3.06e-09	0.46	FALSE
Liver	Dnajc19	gene expression	Dnajc19	0.08	1	0.04	1.8e-05	-5.98	2.18e-09	0.52	FALSE
Liver	Mfn1	gene expression	Mfn1	0.34	23	0.33	3.5e-38	-5.93	3.11e-09	0.52	FALSE
Liver	Dnajc19	mRNA stability	Dnajc19	0.06	1	0.03	5.6e-04	-6	1.92e-09	0.34	FALSE
Liver	Pik3ca	mRNA stability	Pik3ca	0.14	1935	0.1	1.3e-11	-5.76	8.54e-09	0.47	FALSE
NAcc	Gnb4	alternative polyA	NM_001013910.2	0.09	1	0.13	1.3e-14	5.67	1.41e-08	0.31	FALSE
NAcc	Gnb4	alternative polyA	XM_039101981.1	0.06	1	0.09	1.0e-10	-5.67	1.41e-08	0.31	FALSE
NAcc	Gnb4	gene expression	Gnb4	0.03	1694	0.02	4.7e-03	5.35	8.68e-08	0.34	FALSE
NAcc	LOC103691527	gene expression	LOC103691527	0.07	2107	0.04	5.9e-06	5.98	2.25e-09	0.65	FALSE
NAcc	Mfn1	gene expression	Mfn1	0.17	26	0.22	1.3e-24	5.54	3.00e-08	0.49	FALSE
NAcc	Pex5l	gene expression	Pex5l	0.03	2467	0.04	1.6e-05	-5.78	7.58e-09	0.4	FALSE
NAcc	Gnb4	isoform ratio	NM_001013910.2	0.08	36	0.12	5.7e-14	-5.75	9.13e-09	0.5	FALSE
NAcc	Gnb4	isoform ratio	XR_005500258.1	0.06	1	0.06	2.8e-07	-5.85	5.03e-09	0.52	FALSE
NAcc	Ccdc39	intron excision ratio	chr2_116688917_116690264	0.04	2508	0.04	6.9e-06	-5.6	2.17e-08	0.49	FALSE
NAcc	Gnb4	intron excision ratio	chr2_115386834_115389328	0.13	32	0.18	1.5e-20	-5.47	4.43e-08	0.5	FALSE
NAcc	Gnb4	intron excision ratio	chr2_115389413_115400546	0.07	1694	0.09	5.7e-11	5.5	3.85e-08	0.44	FALSE
NAcc	Usp13	intron excision ratio	chr2_115658975_115661336	0.03	1753	0.01	1.5e-02	5.85	4.93e-09	0.36	FALSE
NAcc	Ccdc39	mRNA stability	Ccdc39	0.16	1	0.2	5.0e-23	5.47	4.46e-08	0.04	FALSE
NAcc	Gnb4	mRNA stability	Gnb4	0.05	1694	0.06	3.2e-07	-5.22	1.76e-07	0.5	FALSE
NAcc	Pex5l	mRNA stability	Pex5l	0.02	1	0.02	4.7e-03	-6	1.96e-09	0.03	FALSE
NAcc	Pik3ca	mRNA stability	Pik3ca	0.03	1936	0.03	2.6e-04	-5.76	8.27e-09	0.46	FALSE
OFC	Mfn1	gene expression	Mfn1	0.15	31	0.1	2.7e-03	5.93	3.10e-09	0.4	FALSE
OFC	Ccdc39	mRNA stability	Ccdc39	0.24	501	0.12	7.6e-04	6.14	8.08e-10	0.44	TRUE
PL	Gnb4	alternative polyA	NM_001013910.2	0.12	1694	0.18	1.1e-19	-5.83	5.40e-09	0.52	FALSE
PL	Gnb4	alternative polyA	XM_039101981.1	0.13	35	0.19	5.8e-21	5.76	8.26e-09	0.52	FALSE
PL	Gnb4	isoform ratio	NM_001013910.2	0.12	1	0.18	1.9e-19	5.74	9.57e-09	0.39	FALSE
PL	Gnb4	isoform ratio	XM_039101981.1	0.06	1694	0.07	6.2e-08	5.76	8.45e-09	0.51	FALSE
PL	Gnb4	isoform ratio	XR_005500258.1	0.12	1694	0.04	1.1e-05	6.02	1.74e-09	0.5	FALSE
PL	LOC103691527	isoform ratio	XR_005500860.1	0.04	2107	0.03	4.8e-04	-5.88	4.21e-09	0.53	FALSE
PL	Pex5l	isoform ratio	NM_173152.3	0.03	1	0.05	5.4e-06	-5.49	3.92e-08	0.03	FALSE
PL	Gnb4	intron excision ratio	chr2_115386834_115389328	0.08	1	0.12	2.7e-13	-5.68	1.35e-08	0.32	FALSE
PL	Gnb4	intron excision ratio	chr2_115386834_115400546	0.1	1	0.14	1.7e-15	5.68	1.35e-08	0.32	FALSE
PL	Actl6a	mRNA stability	Actl6a	0.02	28	0.01	1.2e-02	-5.71	1.14e-08	0.34	FALSE
PL	Ccdc39	mRNA stability	Ccdc39	0.2	2508	0.27	4.7e-30	-6.04	1.52e-09	0.53	FALSE
PL	Gnb4	mRNA stability	Gnb4	0.03	1	0.04	4.8e-05	5.74	9.39e-09	0.14	FALSE
PL	Mfn1	mRNA stability	Mfn1	0.04	1785	0.06	5.1e-07	5.43	5.50e-08	0.51	FALSE
PL	Pex5l	mRNA stability	Pex5l	0.02	2467	0.03	3.3e-04	5.54	3.03e-08	0.4	FALSE
PL	Pik3ca	mRNA stability	Pik3ca	0.05	1	0.06	4.5e-07	5.7	1.18e-08	0.41	FALSE
pVTA	Gnb4	alternative polyA	XM_039101981.1	0.06	1694	0.05	2.6e-03	5.76	8.44e-09	0.41	FALSE
pVTA	Ndufb5	gene expression	Ndufb5	0.09	1690	0.08	3.6e-04	5.34	9.04e-08	0.46	FALSE
pVTA	Pex5l	gene expression	Pex5l	0.11	2253	0.07	6.3e-04	-5.84	5.22e-09	0.41	FALSE
pVTA	Gnb4	isoform ratio	NM_001013910.2	0.08	1694	0.06	1.5e-03	-5.33	9.77e-08	0.41	FALSE
pVTA	Gnb4	isoform ratio	XM_039101981.1	0.08	1	0.05	4.2e-03	-5.76	8.48e-09	0.05	FALSE
pVTA	Gnb4	intron excision ratio	chr2_115386834_115400546	0.14	16	0.09	1.3e-04	-5.26	1.42e-07	0.51	FALSE
pVTA	Gnb4	intron excision ratio	chr2_115389413_115400546	0.11	1694	0.07	4.0e-04	5.75	8.70e-09	0.56	FALSE
pVTA	Ccdc39	mRNA stability	Ccdc39	0.09	2090	0.09	8.8e-05	-6.08	1.19e-09	0.44	FALSE
pVTA	Pex5l	mRNA stability	Pex5l	0.09	1	0.07	4.0e-04	-5.85	5.03e-09	0.05	FALSE
pVTA	Pik3ca	mRNA stability	Pik3ca	0.06	1	0.1	6.2e-05	5.91	3.42e-09	0.15	FALSE
RMTg	Kcnmb2	gene expression	Kcnmb2	0.21	147	0.16	3.8e-05	-5.66	1.51e-08	0.52	FALSE
RMTg	Egfem1	mRNA stability	Egfem1	0.2	2480	0.05	2.3e-02	5.36	8.54e-08	0.43	FALSE
RMTg	Fxr1	mRNA stability	Fxr1	0.22	1	0.04	2.4e-02	-6	1.97e-09	0.05	FALSE
RMTg	Mfn1	mRNA stability	Mfn1	0.25	1	0.13	2.9e-04	-5.7	1.18e-08	0.05	FALSE