Hub : Traits : Soleus weight : ← : →

chr2:115,554,411-119,595,215

Trait: Soleus weight

Best TWAS P = 3.67e-10 · Best GWAS P= 5.38e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Gnb4	alternative polyA	NM_001013910.2	0.08	1734	0.08	2.4e-09	-5.76	8.54e-09	0.51	FALSE
Adipose	Gnb4	alternative polyA	XM_039101982.2	0.08	1734	0.08	2.8e-09	5.76	8.41e-09	0.51	FALSE
Adipose	Gnb4	alternative TSS	NM_001013910.2	0.04	1	0.04	8.8e-05	-5.86	4.53e-09	0.08	FALSE
Adipose	Gnb4	alternative TSS	XM_039101982.2	0.04	1	0.03	1.0e-04	5.86	4.53e-09	0.07	FALSE
Adipose	Dnajc19	gene expression	Dnajc19	0.04	2365	0.01	7.3e-02	5.39	7.12e-08	0.53	FALSE
Adipose	Gnb4	gene expression	Gnb4	0.37	114	0.28	1.1e-31	-5.77	7.87e-09	0.51	FALSE
Adipose	Mfn1	gene expression	Mfn1	0.16	1827	0.18	3.9e-19	-5.77	7.96e-09	0.52	FALSE
Adipose	Pik3ca	gene expression	Pik3ca	0.1	1968	0.09	3.0e-10	6	1.95e-09	0.5	FALSE
Adipose	Dnajc19	isoform ratio	XM_063282411.1	0.03	1	0.01	5.7e-02	-6.03	1.59e-09	0.04	FALSE
Adipose	Gnb4	isoform ratio	NM_001013910.2	0.09	22	0.1	8.3e-11	-5.82	5.77e-09	0.51	FALSE
Adipose	Gnb4	intron excision ratio	chr2_117315200_117317694	0.03	1734	0.01	8.7e-03	5.99	2.10e-09	0.46	FALSE
Adipose	Gnb4	intron excision ratio	chr2_117315200_117328912	0.03	1734	0.01	1.0e-02	-5.99	2.10e-09	0.46	FALSE
Adipose	Dnajc19	mRNA stability	Dnajc19	0.03	2365	0.01	2.1e-02	6.01	1.88e-09	0.5	FALSE
Adipose	Gnb4	mRNA stability	Gnb4	0.12	1	0.12	2.8e-13	-5.86	4.59e-09	0.44	FALSE
Adipose	Mfn1	mRNA stability	Mfn1	0.07	1	0.06	9.4e-07	-5.86	4.53e-09	0.42	FALSE
BLA	Gnb4	alternative polyA	NM_001013910.2	0.18	28	0.21	1.5e-11	-5.43	5.69e-08	0.51	FALSE
BLA	Gnb4	alternative polyA	XM_039101982.2	0.19	14	0.22	7.4e-12	5.47	4.44e-08	0.51	FALSE
BLA	LOC103691527	alternative polyA	XR_010064233.1	0.23	2190	0.16	6.6e-09	5.61	2.01e-08	0.49	FALSE
BLA	Mfn1	gene expression	Mfn1	0.1	1827	0.06	2.5e-04	-5.31	1.08e-07	0.46	FALSE
BLA	Ndufb5	gene expression	Ndufb5	0.1	1	0.08	6.6e-05	5.78	7.46e-09	0.05	FALSE
BLA	Pik3ca	gene expression	Pik3ca	0.1	1	0.08	4.3e-05	5.94	2.86e-09	0.15	FALSE
BLA	Usp13	gene expression	Usp13	0.06	1804	0.04	4.1e-03	5.59	2.25e-08	0.39	FALSE
BLA	Zmat3	gene expression	Zmat3	0.15	44	0.15	3.1e-08	-5.89	3.97e-09	0.5	FALSE
BLA	Egfem1	isoform ratio	XM_039102234.2	0.07	1	0.04	3.2e-03	5.83	5.58e-09	0.06	FALSE
BLA	Gnb4	isoform ratio	NM_001013910.2	0.22	47	0.25	2.2e-13	-5.88	4.16e-09	0.52	FALSE
BLA	Gnb4	isoform ratio	XM_063281562.1	0.1	1734	0.06	3.7e-04	5.95	2.68e-09	0.49	FALSE
BLA	Gnb4	isoform ratio	XR_005500258.2	0.2	1734	0.12	4.2e-07	5.76	8.26e-09	0.52	FALSE
BLA	Usp13	isoform ratio	XM_008760924.4	0.11	1804	0.02	2.4e-02	-5.24	1.64e-07	0.23	FALSE
BLA	Gnb4	intron excision ratio	chr2_117315200_117328912	0.19	1	0.18	7.5e-10	-5.78	7.46e-09	0.33	FALSE
BLA	Gnb4	intron excision ratio	chr2_117317775_117328908	0.07	1734	0.07	8.6e-05	5.94	2.85e-09	0.51	FALSE
BLA	Ccdc39	mRNA stability	Ccdc39	0.45	29	0.47	1.5e-27	-5.71	1.10e-08	0.48	FALSE
BLA	Gnb4	mRNA stability	Gnb4	0.12	1734	0.13	1.8e-07	-5.67	1.41e-08	0.53	FALSE
BLA	Kcnmb2	mRNA stability	Kcnmb2	0.07	2184	0.02	4.5e-02	-5.82	5.73e-09	0.5	FALSE
BLA	Mfn1	mRNA stability	Mfn1	0.11	76	0.08	6.5e-05	5.7	1.16e-08	0.49	FALSE
BLA	Pex5l	mRNA stability	Pex5l	0.09	130	0.02	3.9e-02	5.38	7.28e-08	0.32	FALSE
Brain	Gnb4	alternative polyA	NM_001013910.2	0.22	189	0.15	2.0e-13	-5.36	8.15e-08	0.54	FALSE
Brain	Gnb4	alternative polyA	XM_039101982.2	0.22	197	0.15	1.3e-13	5.37	7.73e-08	0.54	FALSE
Brain	Ttc14	alternative TSS	NM_001107666.2	0.12	3	0.08	1.1e-07	-6.14	8.01e-10	0.53	FALSE
Brain	Ttc14	alternative TSS	XM_063281771.1	0.12	3	0.08	5.7e-08	6.14	8.12e-10	0.53	FALSE
Brain	Fxr1	gene expression	Fxr1	0.03	1	0.02	8.0e-03	-5.77	8.09e-09	0.03	FALSE
Brain	Mfn1	gene expression	Mfn1	0.25	97	0.3	5.6e-28	-5.84	5.36e-09	0.56	FALSE
Brain	Pex5l	gene expression	Pex5l	0.05	12	0.06	4.6e-06	-5.39	6.96e-08	0.44	FALSE
Brain	Pik3ca	gene expression	Pik3ca	0.18	197	0.18	1.3e-16	5.96	2.55e-09	0.46	FALSE
Brain	Gnb4	isoform ratio	NM_001013910.2	0.15	1734	0.15	1.6e-13	-6.1	1.03e-09	0.53	FALSE
Brain	Gnb4	isoform ratio	XM_063281562.1	0.03	1	0.02	4.0e-03	5.83	5.50e-09	0.03	FALSE
Brain	Gnb4	intron excision ratio	chr2_117315200_117317694	0.1	1	0.1	1.8e-09	5.92	3.15e-09	0.53	FALSE
Brain	Gnb4	intron excision ratio	chr2_117315200_117328912	0.13	1	0.15	1.5e-13	-5.83	5.50e-09	0.4	FALSE
Brain	Gnb4	intron excision ratio	chr2_117317775_117328908	0.04	1734	0.03	2.1e-03	5.57	2.51e-08	0.5	FALSE
Brain	Pex5l	intron excision ratio	chr2_117693174_117777045	0.02	2536	0.01	5.0e-02	-5.52	3.48e-08	0.29	FALSE
Brain	Ccdc39	mRNA stability	Ccdc39	0.31	20	0.16	9.6e-15	-6.1	1.09e-09	0.52	FALSE
Brain	Fxr1	mRNA stability	Fxr1	0.09	2426	0.05	1.7e-05	6.2	5.60e-10	0.54	FALSE
Brain	Gnb4	mRNA stability	Gnb4	0.07	93	0.07	5.4e-07	-5.31	1.11e-07	0.55	FALSE
Brain	Kcnmb2	mRNA stability	Kcnmb2	0.05	1	0.04	1.0e-04	-5.78	7.31e-09	0.06	FALSE
Brain	Pik3ca	mRNA stability	Pik3ca	0.11	1968	0.1	7.7e-10	-5.31	1.09e-07	0.46	FALSE
Brain	Zfp639	mRNA stability	Zfp639	0.03	1	0.03	8.3e-04	-5.41	6.15e-08	0.03	FALSE
Eye	LOC103691527	gene expression	LOC103691527	0.37	1	0.17	1.3e-03	6.11	1.02e-09	0.06	FALSE
Eye	Usp13	gene expression	Usp13	0.36	1804	0.22	3.1e-04	5.72	1.04e-08	0.4	FALSE
IC	Gnb4	alternative polyA	NM_001013910.2	0.2	1734	0.14	2.1e-06	-6.1	1.06e-09	0.51	FALSE
IC	Gnb4	alternative polyA	XM_039101982.2	0.19	1734	0.13	3.7e-06	6.08	1.18e-09	0.51	FALSE
IC	Mfn1	gene expression	Mfn1	0.12	1	0.08	2.2e-04	-5.86	4.59e-09	0.07	FALSE
IC	Egfem1	isoform ratio	XM_039102234.2	0.1	2528	0.05	4.9e-03	5.31	1.07e-07	0.41	FALSE
IC	Gnb4	isoform ratio	NM_001013910.2	0.19	1734	0.11	2.0e-05	-6.15	7.53e-10	0.51	FALSE
IC	Gnb4	intron excision ratio	chr2_117315200_117328912	0.11	1734	0.05	3.6e-03	-5.83	5.52e-09	0.49	FALSE
IC	Ccdc39	mRNA stability	Ccdc39	0.13	31	0.09	1.3e-04	-5.56	2.71e-08	0.44	FALSE
IC	Mfn1	mRNA stability	Mfn1	0.1	12	0.08	3.2e-04	5.86	4.59e-09	0.48	FALSE
IC	Pex5l	mRNA stability	Pex5l	0.08	2313	0.02	6.8e-02	6.25	4.23e-10	0.3	FALSE
IL	Gnb4	gene expression	Gnb4	0.27	1734	0.24	1.9e-06	5.47	4.38e-08	0.49	FALSE
IL	Mfn1	gene expression	Mfn1	0.18	1	0.2	1.9e-05	-5.32	1.04e-07	0.05	FALSE
IL	Ccdc39	mRNA stability	Ccdc39	0.36	2614	0.26	5.5e-07	-5.8	6.74e-09	0.51	FALSE
IL	Pik3ca	mRNA stability	Pik3ca	0.24	1968	0.19	2.2e-05	-5.9	3.56e-09	0.46	FALSE
LHb	Ndufb5	gene expression	Ndufb5	0.14	1746	0.16	1.2e-04	6	1.98e-09	0.47	FALSE
LHb	Zmat3	gene expression	Zmat3	0.11	1	0	2.7e-01	-5.94	2.86e-09	0.06	FALSE
LHb	Pik3ca	mRNA stability	Pik3ca	0.17	1968	0.21	9.5e-06	-5.92	3.26e-09	0.48	FALSE
Liver	Dnajc19	gene expression	Dnajc19	0.07	1	0.04	3.2e-05	5.96	2.47e-09	0.37	FALSE
Liver	Mfn1	gene expression	Mfn1	0.27	26	0.32	1.4e-36	-5.85	4.96e-09	0.52	FALSE
Liver	Pik3ca	gene expression	Pik3ca	0.04	1	0.03	3.1e-04	5.86	4.53e-09	0.12	FALSE
Liver	Dnajc19	mRNA stability	Dnajc19	0.06	1	0.03	3.9e-04	5.96	2.47e-09	0.15	FALSE
Liver	Pik3ca	mRNA stability	Pik3ca	0.1	1968	0.07	3.3e-08	-5.91	3.40e-09	0.48	FALSE
NAcc	Gnb4	alternative polyA	NM_001013910.2	0.09	1734	0.13	2.9e-19	-6.01	1.84e-09	0.54	FALSE
NAcc	Gnb4	alternative polyA	XM_039101982.2	0.09	1734	0.12	7.6e-18	6.05	1.43e-09	0.54	FALSE
NAcc	Actl6a	gene expression	Actl6a	0.01	1	0.01	5.1e-03	-5.78	7.46e-09	0.03	FALSE
NAcc	LOC103691527	gene expression	LOC103691527	0.06	2190	0.05	4.7e-08	6	1.96e-09	0.63	FALSE
NAcc	Mfn1	gene expression	Mfn1	0.19	72	0.24	2.3e-36	-5.65	1.63e-08	0.52	FALSE
NAcc	Pex5l	gene expression	Pex5l	0.04	2536	0.05	1.4e-08	-5.68	1.35e-08	0.42	FALSE
NAcc	Pik3ca	gene expression	Pik3ca	0.09	1968	0.09	4.8e-13	6.01	1.89e-09	0.53	FALSE
NAcc	Zmat3	gene expression	Zmat3	0.01	1	0.02	6.7e-04	-5.83	5.42e-09	0.04	FALSE
NAcc	Gnb4	isoform ratio	NM_001013910.2	0.1	1734	0.16	4.9e-23	-5.9	3.74e-09	0.52	FALSE
NAcc	Gnb4	isoform ratio	XM_039101982.2	0.05	1734	0.04	2.6e-06	-6.08	1.20e-09	0.5	FALSE
NAcc	Gnb4	isoform ratio	XM_063281562.1	0.06	10	0.07	3.5e-10	5.78	7.46e-09	0.47	FALSE
NAcc	Gnb4	isoform ratio	XR_005500258.2	0.07	1734	0.1	1.4e-15	5.98	2.27e-09	0.65	FALSE
NAcc	Ccdc39	intron excision ratio	chr2_118617147_118618494	0.06	1	0.08	2.3e-12	-6.11	1.03e-09	0.51	FALSE
NAcc	Gnb4	intron excision ratio	chr2_117315200_117317694	0.11	21	0.18	3.4e-26	5.87	4.28e-09	0.44	FALSE
NAcc	Gnb4	intron excision ratio	chr2_117315200_117328912	0.11	20	0.18	5.8e-26	-5.88	4.23e-09	0.43	FALSE
NAcc	Ccdc39	mRNA stability	Ccdc39	0.17	4	0.24	1.6e-35	-6.06	1.37e-09	0.5	FALSE
NAcc	Pik3ca	mRNA stability	Pik3ca	0.01	1968	0.01	1.1e-02	-5.63	1.77e-08	0.41	FALSE
OFC	LOC103691527	isoform ratio	XR_010064230.1	0.17	2190	0.06	1.3e-02	-5.3	1.16e-07	0.29	FALSE
OFC	Ccdc39	mRNA stability	Ccdc39	0.22	344	0.14	4.2e-04	-5.71	1.16e-08	0.43	FALSE
PL	Gnb4	alternative polyA	NM_001013910.2	0.12	1734	0.2	5.6e-21	-5.93	3.08e-09	0.53	FALSE
PL	Gnb4	alternative polyA	XM_039101982.2	0.14	32	0.23	3.1e-25	5.77	8.14e-09	0.54	FALSE
PL	Egfem1	alternative TSS	NM_001415037.1	0.03	2528	0.02	1.8e-03	5.38	7.54e-08	0.36	FALSE
PL	Kcnmb2	gene expression	Kcnmb2	0.03	23	0.03	5.3e-04	5.46	4.84e-08	0.47	FALSE
PL	Pik3ca	gene expression	Pik3ca	0.12	1	0.14	6.3e-15	5.78	7.46e-09	0.4	FALSE
PL	Usp13	gene expression	Usp13	0.05	1	0.06	1.0e-06	5.83	5.47e-09	0.24	FALSE
PL	Gnb4	isoform ratio	NM_001013910.2	0.14	37	0.21	1.3e-22	-5.51	3.64e-08	0.53	FALSE
PL	Gnb4	isoform ratio	XM_063281562.1	0.03	1734	0.03	3.0e-04	5.82	5.85e-09	0.51	FALSE
PL	Gnb4	isoform ratio	XR_005500258.2	0.11	1734	0.04	3.1e-05	6.27	3.67e-10	0.51	TRUE
PL	Gnb4	intron excision ratio	chr2_117315200_117317694	0.09	31	0.11	5.7e-12	5.62	1.87e-08	0.53	FALSE
PL	Gnb4	intron excision ratio	chr2_117315200_117328912	0.11	21	0.14	3.3e-15	-5.68	1.38e-08	0.53	FALSE
PL	Actl6a	mRNA stability	Actl6a	0.02	1	0.03	7.4e-04	5.9	3.63e-09	0.03	FALSE
PL	Ccdc39	mRNA stability	Ccdc39	0.25	68	0.3	7.1e-33	-6.08	1.19e-09	0.5	FALSE
PL	Gnb4	mRNA stability	Gnb4	0.03	59	0.02	1.1e-03	-5.41	6.37e-08	0.45	FALSE
PL	Mfn1	mRNA stability	Mfn1	0.04	1827	0.05	1.4e-06	5.49	3.96e-08	0.51	FALSE
PL	Pik3ca	mRNA stability	Pik3ca	0.04	70	0.05	7.2e-06	-5.21	1.91e-07	0.47	FALSE
pVTA	Gnb4	alternative polyA	NM_001013910.2	0.1	1	0.09	1.5e-07	-5.81	6.34e-09	0.34	FALSE
pVTA	Gnb4	alternative polyA	XM_039101982.2	0.09	1	0.09	8.6e-08	5.81	6.34e-09	0.35	FALSE
pVTA	Ttc14	alternative TSS	NM_001107666.2	0.03	2216	0.02	5.8e-03	-6.22	5.07e-10	0.41	FALSE
pVTA	Ttc14	alternative TSS	XM_063281771.1	0.03	2216	0.02	9.6e-03	6.22	5.13e-10	0.41	FALSE
pVTA	LOC120100799	gene expression	LOC120100799	0.05	1	0.05	1.3e-04	-5.79	7.00e-09	0.04	FALSE
pVTA	Mfn1	gene expression	Mfn1	0.03	17	0.02	8.2e-03	-5.21	1.92e-07	0.48	FALSE
pVTA	Pex5l	gene expression	Pex5l	0.13	2313	0.09	2.4e-07	-5.72	1.04e-08	0.4	FALSE
pVTA	Usp13	gene expression	Usp13	0.06	1784	0.04	2.0e-04	5.59	2.24e-08	0.41	FALSE
pVTA	Zmat3	gene expression	Zmat3	0.04	1	0.04	3.0e-04	-5.77	8.01e-09	0.05	FALSE
pVTA	Gnb4	isoform ratio	NM_001013910.2	0.14	1734	0.13	1.5e-10	-5.74	9.45e-09	0.52	FALSE
pVTA	Gnb4	isoform ratio	XM_063281562.1	0.03	1734	0.02	6.9e-03	5.95	2.66e-09	0.48	FALSE
pVTA	Gnb4	isoform ratio	XR_005500258.2	0.04	1	0.02	1.2e-02	6.09	1.16e-09	0.04	FALSE
pVTA	Gnb4	intron excision ratio	chr2_117315200_117328912	0.1	5	0.1	2.1e-08	-5.29	1.25e-07	0.54	FALSE
pVTA	Gnb4	intron excision ratio	chr2_117317775_117328908	0.07	1734	0.07	2.5e-06	5.78	7.60e-09	0.6	FALSE
pVTA	Ccdc39	mRNA stability	Ccdc39	0.07	22	0.07	3.3e-06	-5.54	2.96e-08	0.45	FALSE
pVTA	Gnb4	mRNA stability	Gnb4	0.05	1	0.06	1.3e-05	-5.83	5.42e-09	0.15	FALSE
RMTg	Egfem1	alternative polyA	XM_063281765.1	0.16	1	0.06	1.0e-02	-5.48	4.23e-08	0.05	FALSE
RMTg	Egfem1	alternative polyA	XM_063281765.1	0.22	1	0.13	3.4e-04	-5.48	4.23e-08	0.05	FALSE
RMTg	Egfem1	gene expression	Egfem1	0.19	1	0.07	7.8e-03	5.89	3.95e-09	0.07	FALSE
RMTg	Egfem1	mRNA stability	Egfem1	0.2	1	0.02	8.8e-02	5.84	5.09e-09	0.05	FALSE
RMTg	Mfn1	mRNA stability	Mfn1	0.29	1	0.1	1.2e-03	5.83	5.47e-09	0.06	FALSE