Hub : Traits : sol weight in grams : ← →

chr2:113,624,043-118,238,955

Best TWAS P=1.210112e-09 · Best GWAS P=7.38696e-10 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Mfn1	alternative TSS	ENSRNOT00000077170	0.04	0.02	blup	1776	0.03	3.5e-04	-5.7	-5.9	4.5e-09	0.94	0.48	0.50	FALSE
2	Adipose	Mfn1	alternative TSS	ENSRNOT00000098575	0.05	0.02	blup	1776	0.03	3.1e-04	-6.0	5.9	4.9e-09	-0.94	0.48	0.49	FALSE
3	Adipose	Dnajc19	alternative TSS	ENSRNOT00000104976	0.03	0.00	top1	1	0.00	1.5e-01	-5.5	5.5	4.5e-08	-0.91	0.07	0.03	FALSE
4	Adipose	Dnajc19	alternative TSS	ENSRNOT00000108781	0.03	0.00	top1	1	0.00	1.6e-01	-5.5	-5.5	4.5e-08	0.91	0.07	0.03	FALSE
5	Adipose	Mfn1	gene expression	ENSRNOG00000011057	0.16	0.17	blup	1776	0.18	3.7e-19	-5.7	-5.7	1.6e-08	0.97	0.50	0.50	FALSE
6	Adipose	Gnb4	gene expression	ENSRNOG00000011070	0.24	0.08	blup	1687	0.10	1.2e-11	-5.8	-6.0	1.6e-09	0.92	0.47	0.53	FALSE
7	Adipose	Kcnmb3	gene expression	ENSRNOG00000027836	0.02	0.02	top1	1	0.02	3.3e-03	-5.7	5.7	1.1e-08	-0.97	0.05	0.03	FALSE
8	Adipose	Usp13	gene expression	ENSRNOG00000030639	0.02	0.01	blup	1748	0.01	9.6e-03	-2.8	5.2	2.5e-07	-0.93	0.45	0.34	FALSE
9	Adipose	Dnajc19	gene expression	ENSRNOG00000049819	0.03	0.01	top1	1	0.01	3.5e-02	-6.0	6.0	1.6e-09	-0.95	0.07	0.03	FALSE
10	Adipose	Mfn1	isoform ratio	ENSRNOT00000098575	0.04	0.02	blup	1776	0.03	3.8e-04	-5.7	5.8	5.4e-09	-0.94	0.48	0.48	FALSE
11	Adipose	Gnb4	isoform ratio	ENSRNOT00000014871	0.04	0.01	blup	1687	0.01	7.7e-03	-5.7	5.2	1.5e-07	-0.95	0.45	0.43	FALSE
12	Adipose	Dnajc19	isoform ratio	ENSRNOT00000109197	0.04	0.01	top1	1	0.01	2.6e-02	-5.5	-5.5	4.5e-08	0.89	0.08	0.03	FALSE
13	Adipose	Mfn1	mRNA stability	ENSRNOG00000011057	0.12	0.02	blup	1776	0.04	3.2e-05	-5.7	-5.1	3.0e-07	0.90	0.49	0.51	TRUE
14	BLA	Mfn1	gene expression	ENSRNOG00000011057	0.11	0.06	blup	1777	0.08	4.0e-05	-3.4	-5.3	9.1e-08	0.94	0.52	0.48	FALSE
15	BLA	Ndufb5	gene expression	ENSRNOG00000011949	0.11	0.08	blup	1696	0.08	2.9e-05	-5.7	6.0	2.0e-09	-0.94	0.49	0.50	FALSE
16	BLA	Usp13	gene expression	ENSRNOG00000030639	0.06	0.06	top1	1	0.06	3.4e-04	-5.4	5.4	7.6e-08	-0.96	0.08	0.04	FALSE
17	BLA	Gnb4	intron excision ratio	chr2:115386834:115400546	0.17	0.16	top1	1	0.16	1.1e-08	-5.7	-5.7	1.2e-08	0.97	0.64	0.34	FALSE
18	BLA	Gnb4	intron excision ratio	chr2:115389409:115400542	0.07	0.04	top1	1	0.04	3.3e-03	-5.7	5.7	1.2e-08	-0.97	0.09	0.05	FALSE
19	BLA	Mfn1	mRNA stability	ENSRNOG00000011057	0.11	0.10	lasso	13	0.10	6.1e-06	-5.8	5.8	8.6e-09	-1.00	0.48	0.52	FALSE
20	BLA	Ccdc39	mRNA stability	ENSRNOG00000011440	0.51	0.37	lasso	13	0.48	2.2e-28	-6.0	-5.9	3.7e-09	0.95	0.49	0.51	FALSE
21	Brain	Dnajc19	alternative TSS	ENSRNOT00000104976	0.03	0.02	top1	1	0.02	3.7e-03	-5.5	5.5	4.5e-08	-0.94	0.08	0.03	FALSE
22	Brain	Dnajc19	alternative TSS	ENSRNOT00000108781	0.03	0.02	top1	1	0.02	3.8e-03	-5.5	-5.5	4.5e-08	0.94	0.08	0.03	FALSE
23	Brain	Mfn1	gene expression	ENSRNOG00000011057	0.27	0.31	lasso	37	0.32	1.0e-30	-5.8	-6.0	2.2e-09	0.96	0.47	0.53	FALSE
24	Brain	Gnb4	gene expression	ENSRNOG00000011070	0.03	0.01	blup	1688	0.02	7.3e-03	-2.9	5.1	3.2e-07	-0.93	0.48	0.39	FALSE
25	Brain	Pex5l	gene expression	ENSRNOG00000011211	0.06	0.09	top1	1	0.09	6.5e-09	-5.7	-5.7	1.2e-08	0.96	0.86	0.13	FALSE
26	Brain	Usp13	gene expression	ENSRNOG00000030639	0.07	0.05	blup	1748	0.06	7.1e-06	-5.8	5.3	1.1e-07	-0.95	0.48	0.52	FALSE
27	Brain	NA	gene expression	ENSRNOG00000067530	0.07	0.05	top1	1	0.05	2.7e-05	-5.9	5.9	3.0e-09	-0.87	0.31	0.45	FALSE
28	Brain	Pex5l	isoform ratio	ENSRNOT00000098944	0.03	0.01	blup	2487	0.02	7.7e-03	-2.8	-5.5	4.4e-08	0.94	0.54	0.37	FALSE
29	Brain	Gnb4	intron excision ratio	chr2:115386834:115389328	0.11	0.08	top1	1	0.08	7.2e-08	-5.8	5.8	5.0e-09	-0.97	0.45	0.54	FALSE
30	Brain	Gnb4	intron excision ratio	chr2:115386834:115400546	0.14	0.13	top1	1	0.13	9.2e-12	-6.0	-6.0	1.9e-09	0.97	0.25	0.75	FALSE
31	Brain	Gnb4	intron excision ratio	chr2:115389409:115400542	0.05	0.01	blup	1688	0.02	3.2e-03	-5.8	5.5	4.1e-08	-0.95	0.45	0.51	FALSE
32	Brain	Fxr1	mRNA stability	ENSRNOG00000051480	0.15	0.11	blup	2333	0.13	9.1e-12	-5.5	6.0	1.7e-09	-0.91	0.50	0.50	FALSE
33	Brain	Pik3ca	mRNA stability	ENSRNOG00000056371	0.16	0.16	blup	1928	0.18	3.5e-16	-5.7	-5.5	3.1e-08	0.98	0.53	0.47	FALSE
34	Eye	Usp13	gene expression	ENSRNOG00000030639	0.36	0.15	blup	1748	0.20	5.7e-04	-5.7	5.6	2.4e-08	-0.96	0.43	0.38	FALSE
35	Eye	NA	gene expression	ENSRNOG00000067530	0.34	0.07	top1	1	0.07	3.7e-02	-5.6	5.6	2.5e-08	-0.84	0.13	0.06	FALSE
36	IL	Mfn1	gene expression	ENSRNOG00000011057	0.17	0.16	top1	1	0.16	9.8e-05	-5.7	-5.7	1.5e-08	0.97	0.10	0.06	FALSE
37	IL	NA	intron excision ratio	chr2:117540154:117563387	0.51	0.01	enet	13	0.10	2.1e-03	-5.4	-5.2	2.1e-07	0.75	0.26	0.33	FALSE
38	IL	Ccdc39	mRNA stability	ENSRNOG00000011440	0.43	0.24	lasso	4	0.36	1.3e-09	-6.1	-6.1	1.2e-09	0.96	0.48	0.52	TRUE
39	IL	Pik3ca	mRNA stability	ENSRNOG00000056371	0.24	0.17	blup	1919	0.21	9.2e-06	-5.8	-5.8	5.7e-09	0.93	0.49	0.49	FALSE
40	LHb	Mfn1	gene expression	ENSRNOG00000011057	0.54	0.20	top1	1	0.20	1.3e-05	-5.7	-5.7	1.2e-08	0.96	0.11	0.07	FALSE
41	LHb	Pex5l	gene expression	ENSRNOG00000011211	0.15	0.07	lasso	4	0.14	4.3e-04	-6.0	-6.0	2.0e-09	0.96	0.55	0.43	FALSE
42	LHb	Ndufb5	gene expression	ENSRNOG00000011949	0.11	0.12	top1	1	0.12	7.2e-04	-5.7	5.7	1.0e-08	-0.97	0.10	0.06	FALSE
43	LHb	Ccdc39	isoform ratio	ENSRNOT00000065469	0.13	0.00	blup	2511	0.02	1.2e-01	-6.1	-5.8	5.3e-09	0.94	0.42	0.43	FALSE
44	LHb	Pik3ca	mRNA stability	ENSRNOG00000056371	0.28	0.16	blup	1919	0.22	7.0e-06	-5.7	-6.0	2.0e-09	0.98	0.50	0.50	FALSE
45	Liver	Mfn1	gene expression	ENSRNOG00000011057	0.31	0.33	lasso	35	0.34	2.9e-38	-5.7	-5.9	4.0e-09	0.99	0.48	0.52	FALSE
46	Liver	Dnajc19	gene expression	ENSRNOG00000049819	0.08	0.06	top1	1	0.06	1.2e-07	-6.0	6.0	2.2e-09	-0.94	0.46	0.52	FALSE
47	Liver	Pik3ca	mRNA stability	ENSRNOG00000056371	0.15	0.09	blup	1927	0.09	4.8e-10	-5.7	-5.7	9.6e-09	0.95	0.53	0.47	FALSE
48	NAcc	Ccdc39	alternative TSS	ENSRNOT00000065469	0.23	0.12	top1	1	0.12	1.4e-03	-5.6	-5.6	2.2e-08	0.83	0.13	0.05	FALSE
49	NAcc	Kcnmb2	gene expression	ENSRNOG00000010094	0.16	0.03	blup	1945	0.09	5.1e-03	-2.9	-5.2	2.5e-07	0.95	0.42	0.32	FALSE
50	NAcc	Ccdc39	gene expression	ENSRNOG00000011440	0.36	0.04	blup	2511	0.19	4.9e-05	2.3	-5.3	1.3e-07	0.80	0.65	0.18	FALSE
51	NAcc	Ccdc39	isoform ratio	ENSRNOT00000065469	0.24	0.10	top1	1	0.10	2.5e-03	-5.6	-5.6	2.2e-08	0.82	0.13	0.05	TRUE
52	NAcc	Pik3ca	mRNA stability	ENSRNOG00000056371	0.20	0.16	top1	1	0.16	2.4e-04	-5.7	-5.7	1.2e-08	0.98	0.10	0.06	FALSE
53	NAcc2	Mfn1	gene expression	ENSRNOG00000011057	0.20	0.17	top1	1	0.17	9.6e-10	-5.8	-5.8	8.5e-09	0.97	0.52	0.48	FALSE
54	NAcc2	NA	gene expression	ENSRNOG00000067530	0.06	0.02	blup	2374	0.04	3.3e-03	-4.1	5.1	3.2e-07	-0.74	0.48	0.32	TRUE
55	NAcc2	Gnb4	intron excision ratio	chr2:115386834:115389328	0.14	0.18	top1	1	0.18	4.9e-10	-5.8	5.8	8.5e-09	-0.97	0.58	0.42	FALSE
56	NAcc2	Gnb4	intron excision ratio	chr2:115386834:115400546	0.17	0.21	top1	1	0.21	1.8e-11	-5.8	-5.8	8.5e-09	0.96	0.58	0.42	FALSE
57	NAcc2	Egfem1	intron excision ratio	chr2:114251885:114258830	0.08	0.04	lasso	13	0.05	7.6e-04	-3.6	5.8	5.0e-09	-0.04	0.43	0.55	TRUE
58	NAcc2	Ccdc39	mRNA stability	ENSRNOG00000011440	0.32	0.31	enet	331	0.33	1.6e-18	-6.0	-5.8	8.1e-09	0.95	0.49	0.51	FALSE
59	OFC	Ccdc39	mRNA stability	ENSRNOG00000011440	0.40	0.23	top1	1	0.23	3.0e-06	-6.0	-6.0	2.0e-09	0.94	0.18	0.11	FALSE
60	OFC	Pik3ca	mRNA stability	ENSRNOG00000056371	0.16	0.05	blup	1919	0.09	4.6e-03	-5.8	-5.8	7.6e-09	0.99	0.37	0.33	FALSE
61	PL	Mfn1	gene expression	ENSRNOG00000011057	0.17	0.20	top1	1	0.20	1.5e-05	-5.7	-5.7	1.5e-08	0.97	0.10	0.06	FALSE
62	PL	Usp13	gene expression	ENSRNOG00000030639	0.27	0.12	blup	1741	0.22	5.7e-06	-5.7	5.2	2.1e-07	-0.92	0.49	0.46	FALSE
63	PL	Mfn1	mRNA stability	ENSRNOG00000011057	0.12	0.12	top1	1	0.12	8.0e-04	-5.7	5.7	1.2e-08	-0.98	0.09	0.05	FALSE
64	PL	Ccdc39	mRNA stability	ENSRNOG00000011440	0.37	0.22	blup	2512	0.28	2.0e-07	-6.1	-5.9	2.7e-09	0.94	0.48	0.52	FALSE
65	PL	Ndufb5	mRNA stability	ENSRNOG00000011949	0.13	0.08	lasso	2	0.09	4.4e-03	-5.7	-5.7	1.4e-08	-0.97	0.45	0.45	FALSE
66	PL	Pik3ca	mRNA stability	ENSRNOG00000056371	0.21	0.02	blup	1919	0.12	9.2e-04	-5.7	-5.7	1.2e-08	0.97	0.49	0.48	FALSE
67	PL2	Dnajc19	alternative TSS	ENSRNOT00000104976	0.05	0.04	top1	1	0.04	2.9e-03	-5.5	5.5	4.5e-08	-0.92	0.09	0.04	FALSE
68	PL2	Dnajc19	alternative TSS	ENSRNOT00000108781	0.05	0.04	top1	1	0.04	3.3e-03	-5.5	-5.5	4.5e-08	0.92	0.09	0.04	FALSE
69	PL2	Mfn1	gene expression	ENSRNOG00000011057	0.20	0.24	enet	362	0.27	4.2e-15	-5.8	-5.4	7.3e-08	0.90	0.48	0.52	TRUE
70	PL2	Gnb4	gene expression	ENSRNOG00000011070	0.04	0.02	blup	1688	0.03	9.8e-03	-2.9	5.4	6.9e-08	-0.96	0.46	0.42	FALSE
71	PL2	Gnb4	intron excision ratio	chr2:115386834:115389328	0.13	0.17	top1	1	0.17	1.8e-09	-5.7	5.7	1.2e-08	-0.96	0.64	0.34	FALSE
72	PL2	Gnb4	intron excision ratio	chr2:115386834:115400546	0.16	0.18	top1	1	0.18	7.0e-10	-5.7	-5.7	1.2e-08	0.96	0.65	0.34	FALSE
73	PL2	Ccdc39	mRNA stability	ENSRNOG00000011440	0.44	0.41	blup	2517	0.48	1.7e-29	-6.0	-5.4	5.3e-08	0.92	0.48	0.52	FALSE
74	PL2	Pik3ca	mRNA stability	ENSRNOG00000056371	0.06	0.04	top1	1	0.04	2.9e-03	-5.7	-5.7	1.2e-08	0.99	0.08	0.04	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.