Hub : Traits : Soleus weight : ← : →

chr2:114,236,315-118,238,955

Trait: Soleus weight

Best TWAS P=7.83e-10 · Best GWAS P=7.39e-10 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Mfn1	alternative TSS	ENSRNOT00000077170	0.04	1776	0.03	3.5e-04	-5.86	4.49e-09	0.5	FALSE
Adipose	Mfn1	alternative TSS	ENSRNOT00000098575	0.05	1776	0.03	3.1e-04	5.85	4.91e-09	0.49	FALSE
Adipose	Dnajc19	alternative TSS	ENSRNOT00000104976	0.03	1	0	1.5e-01	5.47	4.47e-08	0.03	FALSE
Adipose	Dnajc19	alternative TSS	ENSRNOT00000108781	0.03	1	0	1.6e-01	-5.47	4.47e-08	0.03	FALSE
Adipose	Mfn1	gene expression	ENSRNOG00000011057	0.16	1776	0.18	3.7e-19	-5.66	1.56e-08	0.5	FALSE
Adipose	Gnb4	gene expression	ENSRNOG00000011070	0.24	1687	0.1	1.2e-11	-6.04	1.55e-09	0.53	FALSE
Adipose	Kcnmb3	gene expression	ENSRNOG00000027836	0.02	1	0.02	3.3e-03	5.71	1.10e-08	0.03	FALSE
Adipose	Usp13	gene expression	ENSRNOG00000030639	0.02	1748	0.01	9.6e-03	5.16	2.51e-07	0.34	FALSE
Adipose	Dnajc19	gene expression	ENSRNOG00000049819	0.03	1	0.01	3.5e-02	6.04	1.59e-09	0.03	FALSE
Adipose	Mfn1	isoform ratio	ENSRNOT00000098575	0.04	1776	0.03	3.8e-04	5.83	5.38e-09	0.48	FALSE
Adipose	Gnb4	isoform ratio	ENSRNOT00000014871	0.04	1687	0.01	7.7e-03	5.25	1.53e-07	0.43	FALSE
Adipose	Dnajc19	isoform ratio	ENSRNOT00000109197	0.04	1	0.01	2.6e-02	-5.47	4.47e-08	0.03	FALSE
Adipose	Mfn1	mRNA stability	ENSRNOG00000011057	0.12	1776	0.04	3.2e-05	-5.12	3.03e-07	0.51	FALSE
BLA	Mfn1	gene expression	ENSRNOG00000011057	0.11	1777	0.08	4.0e-05	-5.34	9.08e-08	0.48	FALSE
BLA	Ndufb5	gene expression	ENSRNOG00000011949	0.11	1696	0.08	2.9e-05	6	2.03e-09	0.5	FALSE
BLA	Usp13	gene expression	ENSRNOG00000030639	0.06	1	0.06	3.4e-04	5.38	7.61e-08	0.04	FALSE
BLA	Gnb4	intron excision ratio	chr2:115386834:115400546	0.17	1	0.16	1.1e-08	-5.7	1.18e-08	0.34	FALSE
BLA	Gnb4	intron excision ratio	chr2:115389409:115400542	0.07	1	0.04	3.3e-03	5.7	1.18e-08	0.05	FALSE
BLA	Mfn1	mRNA stability	ENSRNOG00000011057	0.11	13	0.1	6.1e-06	5.76	8.59e-09	0.52	FALSE
BLA	Ccdc39	mRNA stability	ENSRNOG00000011440	0.51	13	0.48	2.2e-28	-5.9	3.75e-09	0.51	FALSE
Brain	Dnajc19	alternative TSS	ENSRNOT00000104976	0.03	1	0.02	3.7e-03	5.47	4.46e-08	0.03	FALSE
Brain	Dnajc19	alternative TSS	ENSRNOT00000108781	0.03	1	0.02	3.8e-03	-5.47	4.46e-08	0.03	FALSE
Brain	Mfn1	gene expression	ENSRNOG00000011057	0.27	37	0.32	1.0e-30	-5.98	2.16e-09	0.53	FALSE
Brain	Gnb4	gene expression	ENSRNOG00000011070	0.03	1688	0.02	7.3e-03	5.11	3.15e-07	0.39	FALSE
Brain	Pex5l	gene expression	ENSRNOG00000011211	0.06	1	0.09	6.5e-09	-5.7	1.18e-08	0.13	FALSE
Brain	Usp13	gene expression	ENSRNOG00000030639	0.07	1748	0.06	7.1e-06	5.3	1.13e-07	0.52	FALSE
Brain	ENSRNOG00000067530	gene expression	ENSRNOG00000067530	0.07	1	0.05	2.7e-05	5.93	2.96e-09	0.45	FALSE
Brain	Pex5l	isoform ratio	ENSRNOT00000098944	0.03	2487	0.02	7.7e-03	-5.47	4.42e-08	0.37	FALSE
Brain	Gnb4	intron excision ratio	chr2:115386834:115389328	0.11	1	0.08	7.2e-08	5.85	5.03e-09	0.54	FALSE
Brain	Gnb4	intron excision ratio	chr2:115386834:115400546	0.14	1	0.13	9.2e-12	-6.01	1.90e-09	0.75	FALSE
Brain	Gnb4	intron excision ratio	chr2:115389409:115400542	0.05	1688	0.02	3.2e-03	5.49	4.06e-08	0.51	FALSE
Brain	Fxr1	mRNA stability	ENSRNOG00000051480	0.15	2333	0.13	9.1e-12	6.02	1.70e-09	0.5	FALSE
Brain	Pik3ca	mRNA stability	ENSRNOG00000056371	0.16	1928	0.18	3.5e-16	-5.54	3.07e-08	0.47	FALSE
Eye	Usp13	gene expression	ENSRNOG00000030639	0.36	1748	0.2	5.7e-04	5.58	2.42e-08	0.38	FALSE
Eye	ENSRNOG00000067530	gene expression	ENSRNOG00000067530	0.34	1	0.07	3.7e-02	5.58	2.46e-08	0.06	FALSE
IL	Mfn1	gene expression	ENSRNOG00000011057	0.17	1	0.16	9.8e-05	-5.66	1.52e-08	0.06	FALSE
IL	ENSRNOG00000067530	intron excision ratio	chr2:117540154:117563387	0.51	13	0.1	2.1e-03	-5.19	2.13e-07	0.33	FALSE
IL	Ccdc39	mRNA stability	ENSRNOG00000011440	0.43	4	0.36	1.3e-09	-6.08	1.21e-09	0.52	FALSE
IL	Pik3ca	mRNA stability	ENSRNOG00000056371	0.24	1919	0.21	9.2e-06	-5.82	5.72e-09	0.49	FALSE
LHb	Mfn1	gene expression	ENSRNOG00000011057	0.54	1	0.2	1.3e-05	-5.7	1.18e-08	0.07	FALSE
LHb	Pex5l	gene expression	ENSRNOG00000011211	0.15	4	0.14	4.3e-04	-6	1.98e-09	0.43	FALSE
LHb	Ndufb5	gene expression	ENSRNOG00000011949	0.11	1	0.12	7.2e-04	5.72	1.05e-08	0.06	FALSE
LHb	Ccdc39	isoform ratio	ENSRNOT00000065469	0.13	2511	0.02	1.2e-01	-5.84	5.27e-09	0.43	FALSE
LHb	Pik3ca	mRNA stability	ENSRNOG00000056371	0.28	1919	0.22	7.0e-06	-6	1.97e-09	0.5	FALSE
Liver	Mfn1	gene expression	ENSRNOG00000011057	0.31	35	0.34	2.9e-38	-5.88	3.99e-09	0.52	FALSE
Liver	Dnajc19	gene expression	ENSRNOG00000049819	0.08	1	0.06	1.2e-07	5.98	2.18e-09	0.52	FALSE
Liver	Pik3ca	mRNA stability	ENSRNOG00000056371	0.15	1927	0.09	4.8e-10	-5.74	9.56e-09	0.47	FALSE
NAcc	Kcnmb2	alternative polyA	ENSRNOT00000079254	0.03	1949	0.02	2.3e-02	5.5	3.76e-08	0.41	FALSE
NAcc	Kcnmb2	alternative polyA	ENSRNOT00000083676	0.03	1949	0.01	3.3e-02	-5.58	2.45e-08	0.4	FALSE
NAcc	Mrpl47	alternative polyA	ENSRNOT00000105200	0.03	1694	0.02	1.4e-02	-5.58	2.44e-08	0.38	FALSE
NAcc	Dnajc19	alternative TSS	ENSRNOT00000104976	0.07	1	0.03	2.3e-03	5.5	3.81e-08	0.03	FALSE
NAcc	Dnajc19	alternative TSS	ENSRNOT00000108781	0.07	1	0.03	2.4e-03	-5.5	3.81e-08	0.03	FALSE
NAcc	Mfn1	gene expression	ENSRNOG00000011057	0.19	1	0.2	1.3e-14	-5.76	8.59e-09	0.48	FALSE
NAcc	Mrpl47	isoform ratio	ENSRNOT00000015864	0.03	1694	0.01	2.7e-02	5.5	3.85e-08	0.38	FALSE
NAcc	Mrpl47	isoform ratio	ENSRNOT00000105200	0.03	1694	0.01	3.0e-02	-5.5	3.70e-08	0.39	FALSE
NAcc	Gnb4	intron excision ratio	chr2:115386834:115389328	0.11	1	0.15	4.9e-11	6.15	7.83e-10	0.88	TRUE
NAcc	Gnb4	intron excision ratio	chr2:115386834:115400546	0.15	1686	0.16	3.0e-12	-5.38	7.27e-08	0.51	FALSE
NAcc	Ccdc39	mRNA stability	ENSRNOG00000011440	0.32	1	0.32	2.0e-24	-6.13	8.67e-10	0.66	FALSE
NAcc	Pik3ca	mRNA stability	ENSRNOG00000056371	0.03	1927	0.03	4.0e-03	-5.69	1.27e-08	0.41	FALSE
OFC	Ccdc39	mRNA stability	ENSRNOG00000011440	0.4	1	0.23	3.0e-06	-6	1.96e-09	0.11	FALSE
OFC	Pik3ca	mRNA stability	ENSRNOG00000056371	0.16	1919	0.09	4.6e-03	-5.78	7.59e-09	0.33	FALSE
PL	Dnajc19	alternative TSS	ENSRNOT00000104976	0.04	2270	0.03	4.7e-03	5.7	1.20e-08	0.35	FALSE
PL	Dnajc19	alternative TSS	ENSRNOT00000108781	0.04	2270	0.02	1.3e-02	-5.79	7.08e-09	0.35	FALSE
PL	Mfn1	gene expression	ENSRNOG00000011057	0.13	1	0.19	3.6e-14	-5.7	1.18e-08	0.4	FALSE
PL	Usp13	gene expression	ENSRNOG00000030639	0.07	1747	0.09	4.4e-07	5.65	1.64e-08	0.48	FALSE
PL	Gnb4	intron excision ratio	chr2:115386834:115389328	0.08	1	0.11	1.1e-08	6.07	1.31e-09	0.81	FALSE
PL	Gnb4	intron excision ratio	chr2:115386834:115400546	0.09	14	0.13	7.6e-10	-6.04	1.59e-09	0.52	FALSE
PL	Gnb4	intron excision ratio	chr2:115389409:115400542	0.03	1	0.03	4.0e-03	6.07	1.31e-09	0.05	FALSE
PL	Mfn1	mRNA stability	ENSRNOG00000011057	0.06	1	0.08	8.1e-07	5.98	2.18e-09	0.67	FALSE
PL	Ccdc39	mRNA stability	ENSRNOG00000011440	0.39	62	0.44	3.2e-36	-6.01	1.87e-09	0.52	FALSE
PL	Pik3ca	mRNA stability	ENSRNOG00000056371	0.07	1927	0.07	7.2e-06	-5.63	1.78e-08	0.49	FALSE