Best TWAS P=2.518008e-07 · Best GWAS P=9.013366e-07 conditioned to 0.4228973
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Eye | Casp7 | gene expression | ENSRNOG00000056216 | 0.51 | 0.05 | blup | 2102 | 0.12 | 0.0072 | 4.4 | 5.2 | 2.5e-07 | 0.88 | 0.28 | 0.3 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.