Hub : Traits : Parametrial fat weight : ← : →

chr3:129,554,891-132,693,612

Trait: Parametrial fat weight

Best TWAS P=4.83e-11 · Best GWAS P=1.76e-11 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dstn	gene expression	ENSRNOG00000005924	0.59	1575	0.48	3.4e-60	5.63	1.77e-08	0.08	FALSE
Adipose	Dtd1	gene expression	ENSRNOG00000008746	0.28	19	0.15	5.0e-16	5.44	5.47e-08	0.52	FALSE
Adipose	Snrpb2	mRNA stability	ENSRNOG00000004967	0.04	20	0.01	1.5e-02	-5.92	3.14e-09	0.37	FALSE
Adipose	Dstn	mRNA stability	ENSRNOG00000005924	0.83	184	0.6	1.1e-83	5.45	4.93e-08	0.06	TRUE
Adipose	Sec23b	mRNA stability	ENSRNOG00000008411	0.08	1	0.06	5.6e-07	5.17	2.35e-07	0.18	FALSE
BLA	Kif16b	gene expression	ENSRNOG00000004951	0.04	1	0.04	4.1e-03	6.42	1.36e-10	0.04	FALSE
BLA	Snrpb2	gene expression	ENSRNOG00000004967	0.05	1	0.02	4.4e-02	6.44	1.16e-10	0.04	FALSE
BLA	Pcsk2	gene expression	ENSRNOG00000005438	0.11	1	0.07	1.9e-04	5.75	8.67e-09	0.04	FALSE
BLA	Dstn	gene expression	ENSRNOG00000005924	0.84	268	0.64	9.8e-44	6.04	1.58e-09	0.27	FALSE
BLA	Dtd1	gene expression	ENSRNOG00000008746	0.25	2	0.16	4.4e-09	5.41	6.17e-08	0.4	TRUE
BLA	Otor	gene expression	ENSRNOG00000028721	0.07	1960	0.04	2.7e-03	-5.94	2.93e-09	0.25	TRUE
BLA	Rbbp9	intron excision ratio	chr3:131927367:131929585	0.14	1	0.07	8.2e-05	5.87	4.24e-09	0.61	FALSE
BLA	Rbbp9	intron excision ratio	chr3:131929308:131929585	0.13	1	0.07	7.7e-05	-5.87	4.24e-09	0.51	FALSE
BLA	Pcsk2	mRNA stability	ENSRNOG00000005438	0.23	1	0.15	3.1e-08	-6.43	1.26e-10	0.55	FALSE
BLA	Dstn	mRNA stability	ENSRNOG00000005924	0.45	182	0.39	2.2e-22	6.32	2.63e-10	0.6	FALSE
BLA	Kat14	mRNA stability	ENSRNOG00000007160	0.05	4	0.03	9.8e-03	-5.29	1.25e-07	0.15	FALSE
Brain	Rrbp1	alternative TSS	ENSRNOT00000055602	0.03	1597	0.03	2.1e-03	-5.73	9.81e-09	0.42	FALSE
Brain	Rrbp1	alternative TSS	ENSRNOT00000101060	0.03	1597	0.02	2.7e-03	5.79	7.23e-09	0.4	FALSE
Brain	Snrpb2	gene expression	ENSRNOG00000004967	0.06	1963	0.05	1.0e-05	5.49	4.03e-08	0.4	FALSE
Brain	Pcsk2	gene expression	ENSRNOG00000005438	0.38	1	0.44	3.9e-44	5.83	5.41e-09	0.04	FALSE
Brain	Dstn	gene expression	ENSRNOG00000005924	0.72	189	0.8	3.2e-120	5.92	3.18e-09	0.06	FALSE
Brain	Rrbp1	gene expression	ENSRNOG00000005958	0.14	1597	0.16	4.1e-15	-5.99	2.10e-09	0.34	FALSE
Brain	Sec23b	gene expression	ENSRNOG00000008411	0.78	128	0.8	7.8e-119	5.12	3.02e-07	0.02	FALSE
Brain	Zfp133	gene expression	ENSRNOG00000027955	0.17	1	0.16	2.7e-14	-5.2	1.94e-07	0.15	FALSE
Brain	Otor	gene expression	ENSRNOG00000028721	0.1	25	0.11	5.1e-10	-5.33	9.58e-08	0.35	FALSE
Brain	Snrpb2	intron excision ratio	chr3:130399307:130400989	0.03	1	0.03	5.7e-04	6.36	2.02e-10	0.04	FALSE
Brain	Sec23b	intron excision ratio	chr3:131955920:131958981	0.3	118	0.22	3.0e-20	5.18	2.22e-07	0.09	FALSE
Brain	Snrpb2	mRNA stability	ENSRNOG00000004967	0.03	1963	0.01	1.3e-02	5.38	7.54e-08	0.31	FALSE
Brain	Dstn	mRNA stability	ENSRNOG00000005924	0.71	239	0.52	1.2e-56	5.9	3.69e-09	0.06	FALSE
Brain	Smim26	mRNA stability	ENSRNOG00000036971	0.03	1	0.02	2.7e-03	5.12	3.06e-07	0.04	FALSE
Eye	Dstn	gene expression	ENSRNOG00000005924	0.77	1048	0.25	1.1e-04	6.01	1.82e-09	0.37	FALSE
Eye	Sec23b	gene expression	ENSRNOG00000008411	0.81	19	0.29	2.1e-05	5.71	1.15e-08	0.6	FALSE
Eye	Zfp133	intron excision ratio	chr3:131829590:131840865	0.3	1	0.04	9.9e-02	-5.96	2.54e-09	0.06	FALSE
IL	Pcsk2	gene expression	ENSRNOG00000005438	0.49	1	0.21	7.5e-06	6.34	2.36e-10	0.08	FALSE
IL	Dstn	gene expression	ENSRNOG00000005924	0.79	1574	0.39	2.0e-10	6.21	5.22e-10	0.51	FALSE
IL	ENSRNOG00000067833	gene expression	ENSRNOG00000067833	0.33	9	0.13	5.9e-04	5.33	9.97e-08	0.08	FALSE
IL	Dstn	mRNA stability	ENSRNOG00000005924	0.54	1574	0.34	4.2e-09	5.94	2.93e-09	0.47	FALSE
LHb	Snrpb2	gene expression	ENSRNOG00000004967	0.24	1	0.15	2.3e-04	6.29	3.23e-10	0.05	FALSE
LHb	Dstn	gene expression	ENSRNOG00000005924	0.8	8	0.5	1.3e-13	6.19	6.06e-10	0.36	FALSE
LHb	Rrbp1	gene expression	ENSRNOG00000005958	0.22	1	0.21	1.0e-05	-6.35	2.20e-10	0.07	FALSE
LHb	Dzank1	gene expression	ENSRNOG00000007440	0.14	1804	0.04	4.6e-02	-5.72	1.09e-08	0.4	FALSE
LHb	Otor	gene expression	ENSRNOG00000028721	0.26	5	0.01	1.7e-01	-6.07	1.30e-09	0.22	FALSE
LHb	Kif16b	mRNA stability	ENSRNOG00000004951	0.11	6	0.03	7.3e-02	-5.88	4.21e-09	0.34	FALSE
LHb	Dstn	mRNA stability	ENSRNOG00000005924	0.39	1	0.37	8.7e-10	5.79	7.00e-09	0.04	FALSE
Liver	Kif16b	alternative polyA	ENSRNOT00000036273	0.18	1	0.14	6.7e-15	-6.32	2.55e-10	0.38	FALSE
Liver	Kif16b	alternative polyA	ENSRNOT00000118037	0.18	1	0.14	1.3e-15	6.31	2.76e-10	0.36	FALSE
Liver	Kif16b	gene expression	ENSRNOG00000004951	0.21	12	0.18	3.7e-19	-6.31	2.83e-10	0.58	FALSE
Liver	Dstn	gene expression	ENSRNOG00000005924	0.67	1575	0.53	2.6e-69	5.86	4.60e-09	0.15	FALSE
Liver	Kat14	gene expression	ENSRNOG00000007160	0.05	37	0.04	3.9e-05	-5.41	6.38e-08	0.03	FALSE
Liver	Rbbp9	gene expression	ENSRNOG00000007972	0.12	9	0.08	2.9e-09	5.23	1.74e-07	0.29	FALSE
Liver	Sec23b	gene expression	ENSRNOG00000008411	0.09	1824	0.05	5.2e-06	5.33	1.01e-07	0.67	FALSE
Liver	Dtd1	gene expression	ENSRNOG00000008746	0.2	1829	0.09	1.2e-10	5.3	1.15e-07	0.49	FALSE
Liver	Kif16b	isoform ratio	ENSRNOT00000083061	0.06	1	0.04	4.7e-05	-6.27	3.65e-10	0.15	FALSE
Liver	Kif16b	isoform ratio	ENSRNOT00000118037	0.15	2140	0.13	4.0e-14	6.47	9.50e-11	0.48	FALSE
Liver	Mgme1	isoform ratio	ENSRNOT00000038865	0.03	1	0.02	4.0e-03	-5.36	8.47e-08	0.03	FALSE
Liver	Mgme1	isoform ratio	ENSRNOT00000098696	0.03	1	0.02	3.2e-03	5.36	8.47e-08	0.03	FALSE
Liver	Kif16b	intron excision ratio	chr3:129976371:129996958	0.03	2140	0.01	2.4e-02	-5.22	1.78e-07	0.09	FALSE
Liver	Snrpb2	intron excision ratio	chr3:130399307:130400989	0.04	1	0.03	3.5e-04	6.23	4.71e-10	0.07	FALSE
Liver	Snrpb2	intron excision ratio	chr3:130399832:130400989	0.06	1963	0.03	2.4e-04	-6.46	1.08e-10	0.47	FALSE
Liver	Rbbp9	intron excision ratio	chr3:131927367:131929585	0.29	91	0.21	2.3e-22	5.2	1.96e-07	0.37	FALSE
Liver	Rbbp9	intron excision ratio	chr3:131929308:131929585	0.29	25	0.2	9.7e-22	-5.18	2.17e-07	0.38	FALSE
Liver	Dstn	mRNA stability	ENSRNOG00000005924	0.67	1575	0.5	1.1e-63	5.7	1.22e-08	0.1	FALSE
Liver	Rbbp9	mRNA stability	ENSRNOG00000007972	0.04	1818	0.01	8.2e-03	5.66	1.49e-08	0.62	FALSE
NAcc	Snrpb2	gene expression	ENSRNOG00000004967	0.04	1	0.02	1.4e-02	5.8	6.46e-09	0.03	FALSE
NAcc	Pcsk2	gene expression	ENSRNOG00000005438	0.25	6	0.15	3.4e-11	5.72	1.07e-08	0.32	FALSE
NAcc	Dstn	gene expression	ENSRNOG00000005924	0.84	1	0.7	1.4e-71	6.04	1.51e-09	0.15	FALSE
NAcc	Rrbp1	gene expression	ENSRNOG00000005958	0.11	1	0.11	2.0e-08	-5.89	3.96e-09	0.09	FALSE
NAcc	Otor	gene expression	ENSRNOG00000028721	0.04	1	0.01	5.2e-02	-6.15	7.78e-10	0.03	FALSE
NAcc	Rbbp9	intron excision ratio	chr3:131927367:131929585	0.17	1	0.08	7.7e-07	5.12	3.06e-07	0.13	FALSE
NAcc	Rbbp9	intron excision ratio	chr3:131929308:131929585	0.17	79	0.08	1.7e-06	-5.17	2.29e-07	0.4	FALSE
NAcc	Kif16b	mRNA stability	ENSRNOG00000004951	0.04	27	0.01	5.8e-02	-6.5	7.77e-11	0.47	TRUE
NAcc	Dstn	mRNA stability	ENSRNOG00000005924	0.55	212	0.48	1.3e-39	5.94	2.85e-09	0.14	FALSE
OFC	Pcsk2	gene expression	ENSRNOG00000005438	0.62	9	0.38	5.0e-10	5.18	2.20e-07	0.29	TRUE
OFC	Dstn	gene expression	ENSRNOG00000005924	0.82	41	0.52	1.4e-14	5.94	2.86e-09	0.43	FALSE
OFC	Dstn	mRNA stability	ENSRNOG00000005924	0.29	1574	0.19	3.1e-05	6.18	6.52e-10	0.48	FALSE
PL	Snrpb2	gene expression	ENSRNOG00000004967	0.12	9	0.11	1.3e-08	6.31	2.82e-10	0.41	FALSE
PL	Pcsk2	gene expression	ENSRNOG00000005438	0.15	80	0.18	1.0e-13	6.38	1.76e-10	0.47	FALSE
PL	Dstn	gene expression	ENSRNOG00000005924	0.88	165	0.62	4.1e-59	5.84	5.31e-09	0.07	FALSE
PL	Dtd1	gene expression	ENSRNOG00000008746	0.16	1	0.16	3.3e-12	5.12	3.12e-07	0.29	FALSE
PL	Zfp133	gene expression	ENSRNOG00000027955	0.19	1	0.12	1.3e-09	-5.2	2.01e-07	0.14	FALSE
PL	Otor	gene expression	ENSRNOG00000028721	0.06	1972	0.05	1.0e-04	-6.22	4.99e-10	0.43	FALSE
PL	Snrpb2	intron excision ratio	chr3:130399307:130400989	0.05	1963	0.03	2.9e-03	6.57	5.17e-11	0.44	FALSE
PL	Sec23b	intron excision ratio	chr3:131955920:131958981	0.07	69	0.05	1.2e-04	5.41	6.24e-08	0.35	FALSE
PL	Snrpb2	mRNA stability	ENSRNOG00000004967	0.09	41	0.03	1.4e-03	5.62	1.87e-08	0.19	FALSE
PL	Pcsk2	mRNA stability	ENSRNOG00000005438	0.04	1	0.02	5.4e-03	-6.58	4.83e-11	0.04	TRUE
PL	Dstn	mRNA stability	ENSRNOG00000005924	0.7	52	0.49	6.1e-42	5.7	1.22e-08	0.06	FALSE