Hub : Traits : Parametrial fat weight : ← : →

chr3:129,261,795-132,900,111

Trait: Parametrial fat weight

Best TWAS P=3.08e-11 · Best GWAS P=1.76e-11 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dtd1	gene expression	Dtd1	0.34	12	0.18	1.5e-19	5.35	8.87e-08	0.45	FALSE
Adipose	Dzank1	gene expression	Dzank1	0.1	1802	0.04	3.6e-05	-5.47	4.54e-08	0.8	FALSE
Adipose	Rbbp9	gene expression	Rbbp9	0.11	1820	0.03	2.1e-04	5.43	5.55e-08	0.65	FALSE
Adipose	Kif16b	isoform ratio	XM_006235108.4	0.07	2158	0.03	1.7e-04	5.65	1.59e-08	0.17	FALSE
Adipose	Dstn	mRNA stability	Dstn	0.8	253	0.61	1.5e-84	-5.55	2.90e-08	0.06	FALSE
Adipose	LOC120101717	mRNA stability	LOC120101717	0.05	2365	0.01	9.9e-03	5.4	6.54e-08	0.35	TRUE
BLA	Kif16b	gene expression	Kif16b	0.05	2131	0.02	1.9e-02	6.11	1.02e-09	0.42	FALSE
BLA	Otor	gene expression	Otor	0.06	1963	0.01	1.2e-01	-6.06	1.32e-09	0.24	TRUE
BLA	Scp2d1	gene expression	Scp2d1	0.26	1	0.13	2.1e-07	5.29	1.24e-07	0.8	FALSE
BLA	Snrpb2	gene expression	Snrpb2	0.06	1954	0.01	5.2e-02	6.35	2.13e-10	0.43	FALSE
BLA	Snrpb2	isoform ratio	XM_039105470.1	0.09	7	0.07	1.2e-04	-5.66	1.54e-08	0.3	FALSE
BLA	Rbbp9	intron excision ratio	chr3_131927367_131929585	0.12	1	0.06	2.9e-04	-5.79	6.95e-09	0.14	FALSE
BLA	Rbbp9	intron excision ratio	chr3_131929308_131929585	0.11	1	0.06	4.1e-04	5.79	6.95e-09	0.11	FALSE
BLA	Dstn	mRNA stability	Dstn	0.44	123	0.26	2.1e-14	-6.19	6.08e-10	0.49	FALSE
BLA	Pcsk2	mRNA stability	Pcsk2	0.27	1	0.09	1.5e-05	6.43	1.26e-10	0.48	FALSE
Brain	Rrbp1	alternative TSS	XM_039106605.1	0.02	1593	0.01	1.4e-02	6.15	7.87e-10	0.53	FALSE
Brain	Rrbp1	alternative TSS	XM_230637.10	0.02	1593	0.02	1.2e-02	-6.15	7.93e-10	0.53	FALSE
Brain	Rrbp1	alternative TSS	XM_039106605.1	0.03	1	0.02	3.5e-03	-6.6	4.02e-11	0.14	FALSE
Brain	Rrbp1	alternative TSS	XM_230637.10	0.03	1	0.03	1.7e-03	6.6	4.02e-11	0.22	FALSE
Brain	Dtd1	gene expression	Dtd1	0.2	149	0.19	1.3e-17	-5.39	6.88e-08	0.43	FALSE
Brain	Dzank1	gene expression	Dzank1	0.07	1	0.06	2.0e-06	5.37	7.69e-08	0.38	FALSE
Brain	Kif16b	gene expression	Kif16b	0.15	93	0.1	7.0e-10	-5.26	1.43e-07	0.03	FALSE
Brain	Otor	gene expression	Otor	0.1	1990	0.11	4.9e-10	-6.13	9.04e-10	0.36	FALSE
Brain	Pcsk2	gene expression	Pcsk2	0.38	38	0.46	1.0e-47	-5.77	7.82e-09	0.32	TRUE
Brain	Rrbp1	gene expression	Rrbp1	0.12	17	0.16	3.7e-15	-6.13	8.93e-10	0.25	TRUE
Brain	Snrpb2	gene expression	Snrpb2	0.08	50	0.08	3.2e-08	-5.87	4.24e-09	0.41	FALSE
Brain	Zfp133	gene expression	Zfp133	0.16	107	0.15	8.2e-14	5.26	1.45e-07	0.18	FALSE
Brain	Dzank1	intron excision ratio	chr3_131906549_131908083	0.04	1804	0.02	5.0e-03	5.59	2.30e-08	0.5	FALSE
Brain	LOC120101719	intron excision ratio	chr3_130525654_130567132	0.13	39	0.2	2.1e-18	6.48	9.00e-11	0.42	FALSE
Brain	Snrpb2	intron excision ratio	chr3_130399307_130400989	0.04	1981	0.04	2.9e-04	6.46	1.07e-10	0.44	FALSE
Brain	Dstn	mRNA stability	Dstn	0.5	165	0.37	1.1e-35	-5.9	3.69e-09	0.07	FALSE
Eye	Sec23b	gene expression	Sec23b	0.79	20	0.22	3.0e-04	5.79	6.90e-09	0.5	FALSE
IL	LOC120101719	alternative polyA	XR_005502514.1	0.24	74	0.27	4.2e-07	6.02	1.78e-09	0.41	FALSE
IL	LOC120101719	alternative polyA	XR_005502515.1	0.24	1	0.29	1.1e-07	-5.81	6.40e-09	0.04	FALSE
IL	Rbbp9	alternative polyA	NM_019219.3	0.3	1822	0.14	3.7e-04	-5.29	1.25e-07	0.61	FALSE
IL	Rbbp9	alternative polyA	NM_019219.3	0.34	31	0.14	2.6e-04	-5.59	2.22e-08	0.68	FALSE
IL	Rbbp9	alternative polyA	XM_039104445.1	0.34	42	0.14	2.6e-04	5.65	1.64e-08	0.69	FALSE
IL	LOC120101719	gene expression	LOC120101719	0.19	1	0.08	5.1e-03	-5.77	7.72e-09	0.05	FALSE
IL	Pcsk2	gene expression	Pcsk2	0.5	1455	0.15	2.4e-04	6	1.95e-09	0.33	FALSE
IL	LOC120101719	isoform ratio	XR_005502514.1	0.26	1	0.34	5.5e-09	5.81	6.40e-09	0.04	FALSE
IL	LOC120101719	isoform ratio	XR_005502515.1	0.26	1	0.34	5.4e-09	-5.81	6.40e-09	0.04	FALSE
IL	Rbbp9	isoform ratio	XM_039104444.1	0.24	22	0.08	6.1e-03	5.99	2.05e-09	0.59	FALSE
IL	LOC120101719	intron excision ratio	chr3_130525654_130567132	0.32	1	0.13	5.8e-04	6.2	5.61e-10	0.05	FALSE
IL	Dstn	mRNA stability	Dstn	0.58	237	0.36	1.8e-09	-6.13	8.73e-10	0.5	FALSE
LHb	Otor	gene expression	Otor	0.24	1990	0.01	1.8e-01	-6.17	6.76e-10	0.26	FALSE
LHb	Rrbp1	gene expression	Rrbp1	0.24	1593	0.13	6.3e-04	-5.96	2.53e-09	0.5	FALSE
LHb	Snrpb2	gene expression	Snrpb2	0.3	1981	0.14	3.6e-04	5.94	2.78e-09	0.3	FALSE
LHb	Zfp133	gene expression	Zfp133	0.24	26	0.06	2.0e-02	-5.22	1.78e-07	0.34	FALSE
LHb	Sec23b	intron excision ratio	chr3_131955920_131958981	0.39	35	0.2	1.8e-05	5.31	1.08e-07	0.48	FALSE
LHb	Dstn	mRNA stability	Dstn	0.33	1573	0.24	1.9e-06	6.12	9.30e-10	0.44	FALSE
Liver	Kif16b	alternative polyA	XM_039105041.1	0.16	2158	0.13	6.2e-14	6.38	1.77e-10	0.47	FALSE
Liver	Kif16b	alternative polyA	XM_039105043.1	0.11	2158	0.06	4.2e-07	-6.17	6.88e-10	0.48	FALSE
Liver	Dtd1	gene expression	Dtd1	0.21	1829	0.11	8.4e-12	5.29	1.24e-07	0.5	FALSE
Liver	Kif16b	gene expression	Kif16b	0.24	83	0.2	1.4e-21	6.33	2.46e-10	0.59	FALSE
Liver	LOC120101717	gene expression	LOC120101717	0.05	2365	0.01	1.9e-02	-5.81	6.17e-09	0.21	FALSE
Liver	Kif16b	isoform ratio	NM_001107783.2	0.03	1	0.03	2.2e-04	5.92	3.26e-09	0.03	FALSE
Liver	Kif16b	isoform ratio	XM_039105043.1	0.03	2158	0.01	1.6e-02	-6.21	5.39e-10	0.38	FALSE
Liver	Rbbp9	intron excision ratio	chr3_131927367_131929585	0.3	98	0.21	7.7e-23	-5.27	1.39e-07	0.37	FALSE
Liver	Rbbp9	intron excision ratio	chr3_131929308_131929585	0.3	8	0.21	1.2e-22	-5.26	1.46e-07	0.39	FALSE
Liver	Snrpb2	intron excision ratio	chr3_130399307_130400989	0.04	1	0.04	3.1e-05	-6.22	4.89e-10	0.07	FALSE
Liver	Snrpb2	intron excision ratio	chr3_130399832_130400989	0.05	1	0.05	4.2e-06	6.22	4.89e-10	0.13	FALSE
Liver	Dstn	mRNA stability	Dstn	0.63	1572	0.39	8.2e-46	5.54	3.01e-08	0.09	FALSE
Liver	Rbbp9	mRNA stability	Rbbp9	0.15	1820	0.12	4.7e-13	5.43	5.64e-08	0.63	FALSE
NAcc	Kif16b	alternative polyA	XM_039105041.1	0.06	2158	0.04	5.5e-06	5.92	3.32e-09	0.43	FALSE
NAcc	LOC120101719	alternative polyA	XR_005502514.1	0.11	1	0.15	1.4e-16	6.47	1.01e-10	0.53	FALSE
NAcc	LOC102550304	gene expression	LOC102550304	0.18	7	0.25	7.8e-29	5.24	1.56e-07	0.01	TRUE
NAcc	Otor	gene expression	Otor	0.03	1	0.04	9.3e-06	6.15	7.78e-10	0.08	FALSE
NAcc	Pcsk2	gene expression	Pcsk2	0.09	1455	0.12	1.6e-13	6.44	1.16e-10	0.45	FALSE
NAcc	Rrbp1	gene expression	Rrbp1	0.07	1	0.07	8.1e-09	5.72	1.06e-08	0.04	FALSE
NAcc	Snrpb2	gene expression	Snrpb2	0.04	1981	0.03	1.2e-04	6.23	4.69e-10	0.37	FALSE
NAcc	Zfp133	gene expression	Zfp133	0.09	6	0.09	1.6e-10	-5.24	1.59e-07	0.23	FALSE
NAcc	Kif16b	isoform ratio	XM_006235108.4	0.02	2158	0.02	1.9e-03	5.96	2.58e-09	0.35	FALSE
NAcc	LOC120101719	isoform ratio	XR_005502514.1	0.12	1	0.13	3.4e-15	6.47	1.01e-10	0.53	FALSE
NAcc	Snrpb2	intron excision ratio	chr3_130399307_130400989	0.08	1981	0.07	2.0e-08	6.07	1.25e-09	0.37	FALSE
NAcc	Snrpb2	intron excision ratio	chr3_130399832_130400989	0.08	1981	0.09	1.6e-10	-6.6	4.14e-11	0.52	FALSE
NAcc	Dstn	mRNA stability	Dstn	0.28	1	0.32	2.1e-38	-5.77	8.13e-09	0.03	FALSE
OFC	LOC120101719	alternative polyA	XR_005502514.1	0.35	43	0.3	7.6e-08	5.6	2.10e-08	0.4	FALSE
OFC	LOC120101719	alternative polyA	XR_005502515.1	0.35	86	0.29	1.6e-07	-5.67	1.43e-08	0.4	FALSE
OFC	LOC120101719	gene expression	LOC120101719	0.18	1	0.22	7.2e-06	-6.14	8.34e-10	0.05	FALSE
OFC	Pcsk2	gene expression	Pcsk2	0.56	1	0.36	1.7e-09	-5.81	6.40e-09	0.03	FALSE
OFC	LOC120101719	isoform ratio	XR_005502514.1	0.38	1	0.26	5.6e-07	6.27	3.60e-10	0.12	FALSE
OFC	LOC120101719	intron excision ratio	chr3_130525654_130567132	0.13	10	0.14	2.9e-04	5.29	1.23e-07	0.3	FALSE
OFC	LOC120101719	intron excision ratio	chr3_130529471_130567132	0.14	10	0.15	2.4e-04	-5.26	1.47e-07	0.31	FALSE
OFC	Dstn	mRNA stability	Dstn	0.32	309	0.21	1.3e-05	-6.19	5.92e-10	0.53	FALSE
PL	Kif16b	alternative polyA	XM_039105041.1	0.03	2158	0.03	3.3e-04	6.24	4.49e-10	0.43	FALSE
PL	LOC120101719	alternative polyA	XR_005502514.1	0.3	1	0.35	2.0e-39	6.25	4.17e-10	0.22	FALSE
PL	LOC120101719	alternative polyA	XR_005502515.1	0.34	1	0.37	4.9e-42	-6.38	1.79e-10	0.39	FALSE
PL	Otor	gene expression	Otor	0.04	1	0.06	5.0e-07	6.46	1.03e-10	0.49	FALSE
PL	Pcsk2	gene expression	Pcsk2	0.09	1455	0.15	2.6e-16	6.18	6.59e-10	0.3	FALSE
PL	Snrpb2	gene expression	Snrpb2	0.1	1	0.1	2.1e-11	-6.43	1.26e-10	0.48	FALSE
PL	Zfp133	gene expression	Zfp133	0.14	1	0.14	1.6e-15	5.41	6.28e-08	0.34	TRUE
PL	LOC120101719	isoform ratio	XR_005502514.1	0.43	25	0.41	5.9e-48	5.93	3.05e-09	0.49	FALSE
PL	Snrpb2	isoform ratio	NM_001108592.3	0.05	1	0.06	2.3e-07	-6.5	8.18e-11	0.58	FALSE
PL	Snrpb2	isoform ratio	XM_039105470.1	0.04	1981	0.05	2.3e-06	-5.82	5.74e-09	0.47	FALSE
PL	LOC120101719	intron excision ratio	chr3_130525654_130567132	0.26	1	0.4	3.9e-47	6.51	7.55e-11	0.6	FALSE
PL	LOC120101719	intron excision ratio	chr3_130529471_130567132	0.13	1	0.22	1.2e-23	-6.38	1.79e-10	0.39	FALSE
PL	Sec23b	intron excision ratio	chr3_131955920_131958981	0.09	76	0.1	5.0e-11	-5.67	1.40e-08	0.37	FALSE
PL	Snrpb2	intron excision ratio	chr3_130399307_130400989	0.06	1	0.05	2.4e-06	-6.18	6.40e-10	0.15	FALSE
PL	Snrpb2	intron excision ratio	chr3_130399832_130400989	0.06	1981	0.06	2.7e-07	-6.28	3.36e-10	0.44	FALSE
PL	Dstn	mRNA stability	Dstn	0.54	137	0.41	4.7e-48	-5.65	1.61e-08	0.08	FALSE
PL	Pcsk2	mRNA stability	Pcsk2	0.04	1	0.03	1.1e-04	6.6	4.02e-11	0.66	FALSE
PL	Snrpb2	mRNA stability	Snrpb2	0.02	1981	0.03	2.1e-04	5.93	3.09e-09	0.38	FALSE
pVTA	Smim26	alternative polyA	NM_001106520.1	0.18	15	0.14	1.4e-06	-5.3	1.17e-07	0.38	FALSE
pVTA	Smim26	alternative polyA	XM_006235125.4	0.17	15	0.12	7.7e-06	5.37	7.68e-08	0.4	FALSE
pVTA	Dtd1	gene expression	Dtd1	0.2	15	0.19	1.7e-08	-5.32	1.06e-07	0.31	FALSE
pVTA	Otor	gene expression	Otor	0.11	1	0.13	3.8e-06	6.64	3.08e-11	0.52	TRUE
pVTA	Pcsk2	gene expression	Pcsk2	0.46	29	0.38	2.6e-17	6.41	1.50e-10	0.51	FALSE
pVTA	Rrbp1	gene expression	Rrbp1	0.32	1	0.17	8.4e-08	5.87	4.48e-09	0.08	FALSE
pVTA	Sec23b	gene expression	Sec23b	0.78	339	0.74	3.2e-46	-5.27	1.40e-07	0.28	FALSE
pVTA	Snrpb2	gene expression	Snrpb2	0.07	1954	0.06	1.9e-03	6.45	1.13e-10	0.4	FALSE
pVTA	Rrbp1	intron excision ratio	chr3_131351451_131353366	0.1	94	0.06	1.5e-03	-5.84	5.32e-09	0.63	FALSE
pVTA	Dstn	mRNA stability	Dstn	0.1	1	0.09	9.1e-05	-6.04	1.51e-09	0.06	FALSE
pVTA	Pcsk2	mRNA stability	Pcsk2	0.11	1	0.15	5.3e-07	6.22	5.04e-10	0.2	FALSE
pVTA	Sec23b	mRNA stability	Sec23b	0.38	28	0.4	1.1e-18	5.57	2.53e-08	0.41	FALSE
RMTg	Snrpb2	alternative TSS	XM_039105470.1	0.11	1	0.08	3.2e-03	6.18	6.40e-10	0.05	FALSE
RMTg	Otor	gene expression	Otor	0.1	1990	0.06	1.3e-02	-6.31	2.85e-10	0.3	FALSE
RMTg	Rrbp1	gene expression	Rrbp1	0.28	1	0.26	1.4e-07	5.66	1.47e-08	0.04	FALSE
RMTg	Rbbp9	isoform ratio	NM_019219.3	0.18	1822	0.11	8.3e-04	-5.41	6.28e-08	0.49	FALSE
RMTg	Sec23b	intron excision ratio	chr3_131955920_131958402	0.18	1822	0.04	3.0e-02	-5.28	1.31e-07	0.38	FALSE
RMTg	Sec23b	intron excision ratio	chr3_131958477_131958981	0.16	1822	0.06	9.5e-03	-5.46	4.65e-08	0.32	FALSE
RMTg	Dstn	mRNA stability	Dstn	0.1	1573	0.06	8.3e-03	6.1	1.04e-09	0.33	FALSE