Hub : Traits : Parametrial fat weight : ← : →

chr6:25,671,577-29,167,220

Trait: Parametrial fat weight

Best TWAS P=5.57e-10 · Best GWAS P=5.24e-09 conditioned to 5.65e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Adcy3	gene expression	Adcy3	0.4	1	0.12	1.1e-13	5.61	2.03e-08	0.8	FALSE
Adipose	Efr3b	gene expression	Efr3b	0.11	64	0.09	1.1e-09	-5.25	1.52e-07	0.29	FALSE
Adipose	Itsn2	gene expression	Itsn2	0.02	429	0	1.4e-01	6.2	5.57e-10	0.35	TRUE
Adipose	Cenpo	mRNA stability	Cenpo	0.03	1	0.02	6.6e-03	-5.7	1.23e-08	0.07	FALSE
BLA	Efr3b	alternative TSS	XM_039113098.1	0.08	1	0.05	8.3e-04	-5.23	1.73e-07	0.05	FALSE
BLA	Efr3b	gene expression	Efr3b	0.17	1	0.13	2.1e-07	5.22	1.81e-07	0.35	FALSE
BLA	Ubxn2a	intron excision ratio	chr6_27887989_27893164	0.06	11	0.05	8.6e-04	5.96	2.54e-09	0.76	FALSE
BLA	Ubxn2a	intron excision ratio	chr6_27893322_27894997	0.05	30	0.05	1.6e-03	-5.96	2.59e-09	0.69	FALSE
Brain	Efr3b	gene expression	Efr3b	0.15	1	0.15	7.9e-14	5.62	1.94e-08	0.84	FALSE
Brain	Itsn2	gene expression	Itsn2	0.03	1	0.03	2.0e-03	-5.62	1.92e-08	0.05	FALSE
Brain	Ncoa1	gene expression	Ncoa1	0.41	4	0.17	8.3e-16	5.36	8.39e-08	0.7	FALSE
Brain	RGD1565766	gene expression	RGD1565766	0.1	272	0.07	5.3e-07	5.37	7.85e-08	0.12	FALSE
Brain	Efr3b	mRNA stability	Efr3b	0.11	1	0.11	1.8e-10	5.61	2.03e-08	0.84	FALSE
Brain	Itsn2	mRNA stability	Itsn2	0.03	429	0.01	2.1e-02	-6.04	1.59e-09	0.33	FALSE
Eye	Klhl29	alternative polyA	NM_001106713.3	0.39	1310	0.28	2.8e-05	5.25	1.53e-07	0.54	FALSE
Eye	Klhl29	alternative polyA	XM_017594072.2	0.36	1310	0.26	7.3e-05	-5.22	1.82e-07	0.51	FALSE
Eye	Klhl29	alternative polyA	NM_001106713.3	0.36	1310	0.26	7.6e-05	5.26	1.46e-07	0.53	FALSE
Eye	Klhl29	alternative polyA	XM_006239857.4	0.35	1310	0.24	1.2e-04	-5.25	1.49e-07	0.51	FALSE
IL	Efr3b	gene expression	Efr3b	0.65	35	0.43	1.2e-11	5.62	1.90e-08	0.62	FALSE
IL	Fkbp1b	mRNA stability	Fkbp1b	0.8	1	0.07	8.7e-03	-5.88	4.02e-09	0.06	FALSE
IL	LOC120103502	mRNA stability	LOC120103502	0.28	1	0.26	4.8e-07	-5.24	1.59e-07	0.59	FALSE
LHb	Efr3b	mRNA stability	Efr3b	0.15	27	0.12	7.5e-04	5.38	7.54e-08	0.41	FALSE
Liver	Fam228b	alternative polyA	NM_001419693.1	0.08	1	0.06	5.2e-07	5.78	7.51e-09	0.84	FALSE
Liver	Fam228b	alternative polyA	XM_008764559.3	0.1	1	0.07	6.0e-08	-5.92	3.17e-09	0.92	FALSE
Liver	Fam228b	alternative polyA	NM_001419693.1	0.09	1	0.06	6.5e-07	5.78	7.51e-09	0.84	FALSE
Liver	Fam228b	alternative polyA	XM_008764558.3	0.09	18	0.06	8.0e-07	-5.51	3.56e-08	0.88	FALSE
Liver	Adcy3	gene expression	Adcy3	0.31	1	0.14	3.4e-15	5.64	1.67e-08	0.83	FALSE
Liver	Ncoa1	gene expression	Ncoa1	0.02	1	0.01	4.1e-02	5.7	1.23e-08	0.04	FALSE
Liver	Adcy3	mRNA stability	Adcy3	0.15	96	0.09	6.3e-10	5.71	1.11e-08	0.69	FALSE
NAcc	Dnajc27	gene expression	Dnajc27	0.19	21	0.14	2.3e-16	5.36	8.12e-08	0.49	FALSE
NAcc	Efr3b	gene expression	Efr3b	0.2	1	0.25	3.0e-29	5.56	2.63e-08	0.8	FALSE
NAcc	Kif3c	gene expression	Kif3c	0.03	1	0.02	2.1e-03	-5.22	1.79e-07	0.36	FALSE
OFC	Fkbp1b	alternative polyA	XM_017594336.2	0.19	599	0.07	1.1e-02	-5.27	1.33e-07	0.19	FALSE
OFC	Fkbp1b	alternative polyA	NM_001401262.1	0.24	599	0.07	1.1e-02	-5.18	2.23e-07	0.17	FALSE
OFC	Ncoa1	alternative TSS	NM_001395569.1	0.12	530	0.1	2.1e-03	5.45	4.99e-08	0.46	FALSE
OFC	Ncoa1	alternative TSS	NM_001395569.1	0.11	530	0.1	2.8e-03	5.48	4.24e-08	0.45	FALSE
OFC	Efr3b	mRNA stability	Efr3b	0.15	1189	0.1	2.0e-03	-5.22	1.78e-07	0.44	FALSE
PL	Efr3b	alternative TSS	XM_006239853.2	0.03	1189	0.03	1.2e-04	-5.22	1.83e-07	0.38	FALSE
PL	Efr3b	alternative TSS	XM_006239853.2	0.02	1189	0.03	5.7e-04	-5.2	2.04e-07	0.38	FALSE
PL	Efr3b	alternative TSS	XM_039113097.1	0.02	1189	0.03	8.5e-04	5.2	2.01e-07	0.37	FALSE
PL	Efr3b	gene expression	Efr3b	0.27	38	0.37	4.6e-42	5.25	1.49e-07	0.44	FALSE
PL	Itsn2	gene expression	Itsn2	0.02	429	0.03	5.8e-04	5.88	4.01e-09	0.62	FALSE
PL	LOC120103502	gene expression	LOC120103502	0.26	1	0.14	1.8e-15	-5.23	1.73e-07	0.87	FALSE
PL	Efr3b	isoform ratio	XM_006239853.2	0.02	1189	0.03	7.3e-04	-5.23	1.68e-07	0.41	FALSE
PL	Itsn2	intron excision ratio	chr6_27617212_27638176	0.02	1	0.02	3.9e-03	5.22	1.84e-07	0.03	FALSE
PL	LOC120103499	intron excision ratio	chr6_27617212_27638176	0.02	1	0.02	3.9e-03	5.22	1.84e-07	0.03	FALSE
PL	Ncoa1	intron excision ratio	chr6_27234917_27235003	0.04	1	0.03	1.9e-04	5.47	4.56e-08	0.07	FALSE
PL	Efr3b	mRNA stability	Efr3b	0.12	17	0.18	1.7e-19	-5.19	2.15e-07	0.47	FALSE
pVTA	Ncoa1	alternative TSS	NM_001395569.1	0.06	1	0.03	1.4e-02	5.46	4.77e-08	0.05	FALSE
pVTA	Ncoa1	alternative TSS	NM_001395569.1	0.07	1	0.04	1.2e-02	5.46	4.77e-08	0.05	FALSE
pVTA	Asxl2	gene expression	Asxl2	0.07	1	0.04	7.8e-03	-5.23	1.69e-07	0.06	FALSE
pVTA	Efr3b	gene expression	Efr3b	0.04	1	0.07	3.6e-04	5.44	5.43e-08	0.12	FALSE
pVTA	RGD1565766	gene expression	RGD1565766	0.07	1	0.02	4.6e-02	5.26	1.46e-07	0.04	FALSE