Hub : Traits : Parametrial fat weight : ←

chr10:55,686,136-58,495,301

Trait: Parametrial fat weight

Best TWAS P=1.09e-08 · Best GWAS P=3.51e-08 conditioned to 3.90e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Cyb5d2	gene expression	Cyb5d2	0.07	1	0.04	9.5e-06	5.24	1.64e-07	0.31	FALSE
Adipose	Spns3	gene expression	Spns3	0.03	1252	0.01	7.2e-03	5.49	4.05e-08	0.54	FALSE
Adipose	Tax1bp3	gene expression	Tax1bp3	0.2	1	0.12	2.1e-13	-5.26	1.43e-07	0.68	FALSE
Adipose	Cyb5d2	isoform ratio	NM_001007671.1	0.06	1	0.03	3.7e-04	5.33	1.00e-07	0.17	FALSE
Adipose	Cyb5d2	isoform ratio	XM_006246730.4	0.05	1	0.03	5.3e-04	-5.44	5.22e-08	0.22	FALSE
Adipose	Ankfy1	mRNA stability	Ankfy1	0.13	457	0.11	3.5e-12	5.64	1.69e-08	0.71	FALSE
Adipose	Cyb5d2	mRNA stability	Cyb5d2	0.09	1031	0.06	1.3e-07	5.51	3.62e-08	0.72	FALSE
Adipose	P2rx5	mRNA stability	P2rx5	0.09	10	0.04	5.4e-05	-5.51	3.62e-08	0.73	FALSE
Adipose	Spns3	mRNA stability	Spns3	0.06	1252	0.03	2.5e-04	5.42	6.06e-08	0.66	FALSE
BLA	LOC102547851	alternative polyA	XR_005490347.1	0.26	1	0.19	2.5e-10	-5.38	7.44e-08	0.77	FALSE
BLA	Ankfy1	alternative TSS	XM_039086000.1	0.08	19	0.02	1.9e-02	-5.72	1.09e-08	0.43	TRUE
BLA	Ankfy1	alternative TSS	NM_001107018.2	0.08	1079	0.03	1.5e-02	-5.54	3.01e-08	0.41	FALSE
BLA	Ankfy1	alternative TSS	XM_039086000.1	0.08	50	0.03	1.7e-02	-5.64	1.71e-08	0.43	FALSE
BLA	Atp2a3	gene expression	Atp2a3	0.13	1	0.09	2.4e-05	-5.5	3.74e-08	0.3	FALSE
BLA	Camkk1	gene expression	Camkk1	0.15	1065	0.05	1.8e-03	-5.26	1.47e-07	0.53	FALSE
BLA	Cyb5d2	gene expression	Cyb5d2	0.08	165	0.04	4.8e-03	5.29	1.25e-07	0.65	FALSE
BLA	Smtnl2	gene expression	Smtnl2	0.07	1371	0.02	4.4e-02	5.41	6.27e-08	0.37	FALSE
BLA	Tekt1	gene expression	Tekt1	0.07	13	0.04	5.8e-03	-5.29	1.24e-07	0.39	FALSE
BLA	Zzef1	gene expression	Zzef1	0.13	27	0.07	1.3e-04	5.24	1.64e-07	0.74	FALSE
BLA	LOC102547851	isoform ratio	XR_005490347.1	0.24	1	0.2	6.6e-11	-5.38	7.44e-08	0.77	FALSE
BLA	Cyb5d2	intron excision ratio	chr10_57407529_57412543	0.08	1	0.06	5.3e-04	5.38	7.44e-08	0.05	FALSE
Brain	Wscd1	alternative TSS	XM_017597102.2	0.11	1	0.05	1.3e-05	-5.24	1.64e-07	0.5	FALSE
Brain	Wscd1	alternative TSS	XM_017597102.2	0.12	2405	0.07	6.2e-07	5.24	1.62e-07	0.7	FALSE
Brain	Wscd1	alternative TSS	XM_017597103.2	0.11	1	0.1	1.3e-09	5.22	1.83e-07	0.66	FALSE
Brain	Ankfy1	gene expression	Ankfy1	0.08	1	0.08	9.6e-08	5.32	1.01e-07	0.65	FALSE
Brain	RGD1304728	gene expression	RGD1304728	0.22	109	0.23	2.4e-21	5.38	7.58e-08	0.65	FALSE
Brain	Spns3	gene expression	Spns3	0.04	1	0.04	1.8e-04	-5.19	2.05e-07	0.06	FALSE
Brain	Tekt1	gene expression	Tekt1	0.08	61	0.07	4.6e-07	-5.31	1.12e-07	0.31	FALSE
Brain	Zzef1	gene expression	Zzef1	0.36	23	0.33	6.0e-32	5.19	2.10e-07	0.74	FALSE
Brain	Cyb5d2	intron excision ratio	chr10_57400881_57407389	0.04	1	0.04	6.2e-05	5.49	3.94e-08	0.27	FALSE
Brain	Wscd1	intron excision ratio	chr10_56386447_56396014	0.11	24	0.14	1.1e-12	5.37	7.83e-08	0.65	FALSE
Brain	Med31	mRNA stability	Med31	0.07	1	0.08	1.2e-07	5.22	1.83e-07	0.54	FALSE
IL	Camkk1	gene expression	Camkk1	0.33	1065	0.06	1.4e-02	-5.57	2.57e-08	0.56	FALSE
IL	RGD1304728	gene expression	RGD1304728	0.38	1701	0.08	5.4e-03	-5.32	1.06e-07	0.47	FALSE
IL	Emc6	isoform ratio	NM_001105806.2	0.29	1	0.04	3.2e-02	-5.4	6.74e-08	0.06	FALSE
IL	Emc6	isoform ratio	XM_006246669.4	0.3	1	0.05	2.6e-02	5.4	6.74e-08	0.06	FALSE
IL	Ube2g1	intron excision ratio	chr10_57282306_57292178	0.19	1177	0.05	2.8e-02	-5.56	2.66e-08	0.34	FALSE
LHb	RGD1304728	gene expression	RGD1304728	0.25	27	0.08	6.1e-03	5.63	1.81e-08	0.29	FALSE
Liver	Cyb5d2	alternative polyA	NM_001007671.1	0.05	1	0.04	7.9e-05	5.44	5.22e-08	0.16	FALSE
Liver	Cyb5d2	alternative polyA	XM_006246730.4	0.05	1	0.04	8.0e-05	-5.48	4.23e-08	0.17	FALSE
Liver	Cyb5d2	gene expression	Cyb5d2	0.21	1031	0.15	1.5e-16	-5.6	2.15e-08	0.75	FALSE
Liver	Slc13a5	gene expression	Slc13a5	0.36	1599	0.22	1.6e-23	-5.17	2.30e-07	0.67	FALSE
Liver	Spns2	gene expression	Spns2	0.02	1217	0.01	2.0e-02	-5.47	4.47e-08	0.39	FALSE
Liver	Txndc17	gene expression	Txndc17	0.31	1	0.09	1.1e-09	-5.3	1.17e-07	0.66	FALSE
Liver	Cyb5d2	isoform ratio	NM_001007671.1	0.03	1031	0.02	5.5e-03	-5.62	1.96e-08	0.52	FALSE
Liver	Cyb5d2	isoform ratio	XM_006246730.4	0.03	20	0.02	4.9e-03	-5.54	2.97e-08	0.5	FALSE
Liver	RGD1304728	isoform ratio	XM_340837.8	0.07	162	0.04	1.3e-05	-5.67	1.40e-08	0.33	FALSE
Liver	RGD1304728	intron excision ratio	chr10_56785576_56788896	0.08	1	0.04	5.9e-05	-5.21	1.88e-07	0.14	FALSE
Liver	Ube2g1	intron excision ratio	chr10_57226312_57282204	0.03	1	0.02	4.9e-03	-5.48	4.23e-08	0.04	FALSE
Liver	Txndc17	mRNA stability	Txndc17	0.05	1699	0.04	3.9e-05	5.22	1.79e-07	0.58	FALSE
NAcc	Emc6	alternative polyA	NM_001105806.2	0.07	1	0.04	1.6e-05	-5.31	1.11e-07	0.48	FALSE
NAcc	Emc6	alternative polyA	XM_006246669.4	0.07	1	0.04	1.1e-05	5.49	3.94e-08	0.68	FALSE
NAcc	LOC102547851	alternative polyA	XR_005490347.1	0.04	1912	0.03	4.2e-04	5.2	2.03e-07	0.58	FALSE
NAcc	RGD1304728	gene expression	RGD1304728	0.08	125	0.08	1.4e-09	5.67	1.41e-08	0.64	FALSE
NAcc	Zzef1	gene expression	Zzef1	0.06	1	0.05	2.1e-06	-5.38	7.44e-08	0.65	FALSE
NAcc	Zzef1	intron excision ratio	chr10_57487113_57488694	0.02	1	0.02	3.5e-03	5.24	1.64e-07	0.04	FALSE
NAcc	Med31	mRNA stability	Med31	0.14	1	0.11	2.4e-12	5.38	7.44e-08	0.75	FALSE
OFC	Zzef1	gene expression	Zzef1	0.29	18	0.09	3.3e-03	5.24	1.64e-07	0.45	FALSE
PL	LOC102547851	alternative polyA	XR_005490347.1	0.02	1912	0	1.4e-01	5.37	7.81e-08	0.47	FALSE
PL	Atp2a3	gene expression	Atp2a3	0.05	1062	0.02	9.8e-04	5.26	1.40e-07	0.56	FALSE
PL	Camkk1	gene expression	Camkk1	0.21	17	0.16	2.3e-17	-5.56	2.75e-08	0.81	FALSE
PL	RGD1304728	gene expression	RGD1304728	0.23	1701	0.15	5.4e-16	-5.55	2.92e-08	0.66	FALSE
PL	Tekt1	gene expression	Tekt1	0.07	115	0.06	1.5e-07	-5.66	1.50e-08	0.66	FALSE
PL	Zzef1	gene expression	Zzef1	0.26	1	0.22	4.1e-24	-5.24	1.64e-07	0.56	FALSE
PL	Camkk1	intron excision ratio	chr10_57637483_57644236	0.04	1	0.03	1.3e-04	5.5	3.74e-08	0.26	FALSE
PL	Camkk1	intron excision ratio	chr10_57644145_57644236	0.1	1	0.11	7.5e-12	-5.49	3.94e-08	0.86	FALSE
PL	Med31	mRNA stability	Med31	0.11	24	0.08	1.6e-09	-5.31	1.09e-07	0.65	FALSE
pVTA	Ankfy1	gene expression	Ankfy1	0.15	1	0.17	1.2e-07	5.3	1.18e-07	0.53	FALSE
pVTA	Cyb5d2	gene expression	Cyb5d2	0.11	1	0.11	2.2e-05	5.24	1.64e-07	0.1	FALSE
pVTA	RGD1304728	gene expression	RGD1304728	0.12	106	0.14	1.6e-06	5.31	1.11e-07	0.64	FALSE
pVTA	Txndc17	gene expression	Txndc17	0.07	149	0.02	3.7e-02	-5.19	2.08e-07	0.44	FALSE
pVTA	Zzef1	gene expression	Zzef1	0.2	1031	0.21	1.4e-09	5.57	2.58e-08	0.76	FALSE
pVTA	Cyb5d2	isoform ratio	NM_001007671.1	0.07	44	0.06	2.2e-03	5.59	2.26e-08	0.45	FALSE
pVTA	LOC102547851	intron excision ratio	chr10_56559337_56565515	0.11	1	0.1	3.8e-05	5.33	1.00e-07	0.29	FALSE
RMTg	Tekt1	gene expression	Tekt1	0.13	18	0.06	1.1e-02	5.58	2.42e-08	0.42	FALSE