Best TWAS P=1.19299e-08 · Best GWAS P=6.218523e-06 conditioned to 0.9875809
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | PL | Ccng1 | gene expression | ENSRNOG00000003256 | 0.5 | 0.06 | blup | 2175 | 0.19 | 1.9e-14 | -4 | 5.7 | 1.2e-08 | -0.79 | 0.48 | 0.49 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.