Best TWAS P=1.712348e-10 · Best GWAS P=0.06683232 conditioned to 0.2060356
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Vangl2 | intron excision ratio | chr13:84474817:84484375 | 0.09 | 0.04 | enet | 145 | 0.04 | 0.00042 | 1.7 | 6.4 | 1.7e-10 | 0.46 | 0.04 | 0.03 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.