Best TWAS P=1.768211e-07 · Best GWAS P=0.2140263 conditioned to 1.657257e-05
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NAcc | NA | intron excision ratio | chr5:157445440:157447247 | 0.03 | 0.02 | enet | 134 | 0.04 | 0.00067 | 1.2 | -5.2 | 1.8e-07 | 0.48 | 0.03 | 0.03 | TRUE |
2 | NAcc | NA | intron excision ratio | chr5:157445440:157447247 | 0.03 | 0.02 | enet | 134 | 0.04 | 0.00067 | 1.2 | -5.2 | 1.8e-07 | 0.48 | 0.03 | 0.03 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.