Best TWAS P=6.452021e-12 · Best GWAS P=0.002127152 conditioned to 1.917988e-12
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Ddx25 | gene expression | ENSRNOG00000012260 | 0.7 | 0.01 | lasso | 17 | 0.03 | 0.00035 | -1.2 | 6.9 | 6.5e-12 | -0.9 | 0.03 | 0.05 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.