Best TWAS P=3.345508e-07 · Best GWAS P=0.003261631 conditioned to 0.01913257
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Acnat1 | isoform ratio | ENSRNOT00000078547 | 0.36 | 0.19 | enet | 118 | 0.2 | 1.2e-21 | -2.8 | 5.1 | 3.3e-07 | -0.12 | 0.1 | 0.39 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.