Best TWAS P=1.278021e-07 · Best GWAS P=1.622497e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | IL | Nts | gene expression | ENSRNOG00000004179 | 0.22 | 0.09 | top1 | 1 | 0.09 | 2.9e-03 | -5.3 | -5.3 | 1.3e-07 | 0.97 | 0.13 | 0.05 | TRUE |
| 2 | LHb | Slc6a15 | gene expression | ENSRNOG00000027468 | 0.31 | 0.18 | blup | 2513 | 0.26 | 5.6e-07 | -4.7 | 5.1 | 2.7e-07 | -0.96 | 0.48 | 0.52 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.