Best TWAS P=3.775548e-08 · Best GWAS P=6.003867e-09 conditioned to 0.05366824
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NAcc | Tmtc2 | gene expression | ENSRNOG00000004585 | 0.14 | 0.08 | blup | 2354 | 0.08 | 1.2e-06 | -5.7 | 5.5 | 3.8e-08 | -0.92 | 0.21 | 0.79 | TRUE |
| 2 | NAcc | Tmtc2 | intron excision ratio | chr7:40543989:40545542 | 0.09 | 0.05 | lasso | 11 | 0.06 | 1.3e-05 | -4.7 | -5.3 | 1.3e-07 | 0.89 | 0.46 | 0.53 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.