Best TWAS P=3.41e-08 · Best GWAS P=2.76e-08 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain | Erich2 | alternative TSS | NM_001024311.1 | 0.02 | 1 | 0.02 | 6.5e-03 | 5.47 | 4.41e-08 | 0.1 | FALSE |
| Brain | Erich2 | alternative TSS | XM_006234340.4 | 0.02 | 1 | 0.02 | 4.6e-03 | -5.47 | 4.41e-08 | 0.11 | FALSE |
| Brain | Erich2 | alternative TSS | NM_001024311.1 | 0.03 | 1 | 0.03 | 4.2e-04 | 5.47 | 4.41e-08 | 0.25 | FALSE |
| Brain | Erich2 | alternative TSS | XM_006234340.4 | 0.03 | 1 | 0.04 | 2.1e-04 | -5.47 | 4.41e-08 | 0.3 | FALSE |
| Brain | Erich2 | gene expression | Erich2 | 0.04 | 8 | 0.05 | 1.3e-05 | 5.52 | 3.41e-08 | 0.74 | TRUE |
| IL | Erich2 | gene expression | Erich2 | 0.3 | 829 | 0.06 | 1.4e-02 | 5.4 | 6.55e-08 | 0.4 | FALSE |
| NAcc | Tlk1 | alternative TSS | XM_039104853.1 | 0.05 | 778 | 0.02 | 3.2e-03 | 5.43 | 5.59e-08 | 0.54 | FALSE |
| NAcc | Tlk1 | intron excision ratio | chr3_55559028_55559717 | 0.02 | 1 | 0 | 9.4e-02 | 5.23 | 1.70e-07 | 0.03 | FALSE |
| pVTA | Gad1 | mRNA stability | Gad1 | 0.13 | 900 | 0.05 | 2.4e-03 | 5.27 | 1.35e-07 | 0.5 | FALSE |
| RMTg | Mettl8 | alternative TSS | XM_008761954.3 | 0.12 | 101 | 0.06 | 1.3e-02 | 5.31 | 1.10e-07 | 0.49 | FALSE |