Hub : Traits : Tibia length in mm : ← →

chr7:26,575,816-30,734,621

Best TWAS P=5.545223e-11 · Best GWAS P=9.647113e-11 conditioned to 0.01023096

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Elk3	gene expression	ENSRNOG00000004367	0.11	0.05	blup	2579	0.05	2.5e-06	-4.1	5.3	9.4e-08	-0.48	0.74	0.26	FALSE
2	Adipose	Vezt	gene expression	ENSRNOG00000006514	0.11	0.08	top1	1	0.08	3.2e-09	-5.2	-5.2	1.5e-07	0.67	0.96	0.04	FALSE
3	Adipose	Ndufa12	gene expression	ENSRNOG00000007407	0.34	0.19	lasso	16	0.20	1.0e-21	-5.5	-5.6	2.7e-08	0.73	0.88	0.12	FALSE
4	Adipose	Cep83	intron excision ratio	chr7:29322957:29325469	0.03	0.01	blup	2703	0.02	1.8e-03	-6.0	-5.3	1.4e-07	0.74	0.46	0.44	FALSE
5	Adipose	Vezt	mRNA stability	ENSRNOG00000006514	0.07	0.04	blup	2570	0.06	5.0e-07	-5.7	-6.6	5.5e-11	0.71	0.39	0.61	TRUE
6	BLA	Ntn4	gene expression	ENSRNOG00000005573	0.06	0.02	blup	2475	0.03	8.1e-03	2.2	5.9	4.0e-09	-0.60	0.47	0.31	FALSE
7	BLA	Vezt	gene expression	ENSRNOG00000006514	0.32	0.25	enet	97	0.30	1.1e-16	-6.3	-6.2	6.5e-10	0.68	0.42	0.58	FALSE
8	BLA	Metap2	gene expression	ENSRNOG00000021881	0.08	0.07	top1	1	0.07	1.9e-04	-5.3	5.3	1.4e-07	-0.73	0.10	0.04	FALSE
9	BLA	Mir331	gene expression	ENSRNOG00000035543	0.06	0.04	blup	2366	0.06	5.1e-04	-5.3	5.9	4.7e-09	-0.76	0.70	0.27	FALSE
10	BLA	Fgd6	gene expression	ENSRNOG00000054515	0.11	0.13	top1	1	0.13	2.7e-07	-5.4	-5.4	5.9e-08	0.78	0.84	0.10	FALSE
11	BLA	Lta4h	intron excision ratio	chr7:27997602:27999743	0.07	0.01	blup	2332	0.02	2.6e-02	-4.6	-5.6	2.2e-08	0.53	0.50	0.39	FALSE
12	BLA	Vezt	mRNA stability	ENSRNOG00000006514	0.40	0.42	top1	1	0.42	4.0e-24	-5.4	5.4	5.6e-08	-0.78	0.89	0.11	FALSE
13	BLA	Plxnc1	mRNA stability	ENSRNOG00000007970	0.11	0.11	top1	1	0.11	3.0e-06	-5.2	5.2	1.7e-07	-0.79	0.36	0.04	FALSE
14	Brain	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.06	0.02	top1	1	0.02	3.3e-03	-5.2	5.2	2.0e-07	-0.36	0.13	0.06	FALSE
15	Brain	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.06	0.02	top1	1	0.02	4.8e-03	-5.2	5.2	2.0e-07	-0.36	0.12	0.05	FALSE
16	Brain	Vezt	gene expression	ENSRNOG00000006514	0.24	0.22	blup	2571	0.23	1.2e-20	-5.7	-5.7	1.0e-08	0.70	0.79	0.21	FALSE
17	Brain	Ndufa12	gene expression	ENSRNOG00000007407	0.49	0.32	blup	2574	0.34	6.1e-32	-5.5	-5.6	1.7e-08	0.69	0.88	0.12	FALSE
18	Brain	Fgd6	gene expression	ENSRNOG00000054515	0.16	0.23	top1	1	0.23	8.6e-21	-5.5	-5.5	4.6e-08	0.74	0.88	0.12	FALSE
19	Brain	AABR07056633.1	isoform ratio	ENSRNOT00000094647	0.03	0.00	blup	2953	0.01	7.7e-02	2.1	5.2	1.7e-07	-0.38	0.45	0.22	FALSE
20	Brain	Lta4h	intron excision ratio	chr7:27997602:27999743	0.04	0.02	top1	1	0.02	4.8e-03	-5.7	-5.7	9.3e-09	0.54	0.07	0.34	FALSE
21	Brain	Lta4h	mRNA stability	ENSRNOG00000004494	0.05	0.02	blup	2332	0.03	9.8e-04	-5.0	5.5	4.5e-08	-0.63	0.51	0.41	FALSE
22	Brain	Vezt	mRNA stability	ENSRNOG00000006514	0.20	0.20	lasso	28	0.20	1.6e-18	-5.5	5.8	8.5e-09	-0.70	0.71	0.29	FALSE
23	Eye	Fgd6	gene expression	ENSRNOG00000054515	0.52	0.13	blup	2560	0.15	2.3e-03	-5.4	-6.2	6.0e-10	0.78	0.40	0.23	FALSE
24	Eye	Elk3	isoform ratio	ENSRNOT00000005911	0.36	0.01	blup	2579	0.10	1.2e-02	-5.0	-5.6	2.1e-08	0.58	0.36	0.22	FALSE
25	IL	Vezt	gene expression	ENSRNOG00000006514	0.29	0.20	lasso	4	0.26	7.2e-07	-5.5	-5.3	1.2e-07	0.67	0.73	0.25	FALSE
26	IL	Vezt	mRNA stability	ENSRNOG00000006514	0.23	0.06	blup	2568	0.10	2.4e-03	-5.4	6.5	8.1e-11	-0.76	0.48	0.40	FALSE
27	LHb	Nr2c1	alternative polyA	ENSRNOT00000009578	0.20	0.19	top1	1	0.19	2.6e-05	-5.3	5.3	9.9e-08	-0.63	0.14	0.05	FALSE
28	LHb	Nr2c1	alternative polyA	ENSRNOT00000089228	0.32	0.21	top1	1	0.21	8.9e-06	-5.3	-5.3	9.9e-08	0.62	0.15	0.05	FALSE
29	LHb	Cdk17	isoform ratio	ENSRNOT00000109496	0.18	0.05	blup	2984	0.11	1.4e-03	-5.2	6.1	1.3e-09	-0.45	0.47	0.30	FALSE
30	LHb	Vezt	mRNA stability	ENSRNOG00000006514	0.40	0.20	enet	84	0.21	1.1e-05	-5.6	5.7	1.1e-08	-0.70	0.60	0.40	FALSE
31	Liver	Nedd1	gene expression	ENSRNOG00000004011	0.20	0.24	top1	1	0.24	8.6e-27	-5.3	-5.3	1.2e-07	0.26	0.40	0.60	FALSE
32	Liver	Amdhd1	gene expression	ENSRNOG00000005266	0.37	0.31	lasso	40	0.34	1.7e-39	-5.0	-5.4	6.1e-08	0.55	0.49	0.51	FALSE
33	Liver	Vezt	gene expression	ENSRNOG00000006514	0.14	0.12	enet	322	0.14	1.7e-15	-5.6	-5.2	1.8e-07	0.48	0.34	0.66	FALSE
34	Liver	Ndufa12	gene expression	ENSRNOG00000007407	0.42	0.43	enet	320	0.46	1.8e-56	-5.5	-5.3	1.1e-07	0.71	0.88	0.12	FALSE
35	Liver	Snrpf	mRNA stability	ENSRNOG00000005556	0.03	0.02	top1	1	0.02	1.4e-03	-5.6	-5.6	1.7e-08	0.56	0.07	0.06	FALSE
36	NAcc	Vezt	gene expression	ENSRNOG00000006514	0.23	0.14	blup	2568	0.19	5.5e-05	-5.4	-6.1	1.0e-09	0.71	0.65	0.31	FALSE
37	NAcc2	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.05	0.05	top1	1	0.05	1.4e-03	-5.3	5.3	1.2e-07	-0.39	0.13	0.06	FALSE
38	NAcc2	AABR07056633.1	alternative TSS	ENSRNOT00000104436	0.05	0.05	top1	1	0.04	1.8e-03	-5.3	-5.3	1.2e-07	0.39	0.12	0.06	FALSE
39	NAcc2	AABR07056633.1	alternative TSS	ENSRNOT00000094647	0.06	0.05	top1	1	0.05	7.5e-04	-5.3	5.3	1.2e-07	-0.39	0.14	0.08	FALSE
40	NAcc2	AABR07056633.1	alternative TSS	ENSRNOT00000104436	0.06	0.05	top1	1	0.05	9.2e-04	-5.3	-5.3	1.2e-07	0.39	0.14	0.08	FALSE
41	NAcc2	Vezt	gene expression	ENSRNOG00000006514	0.08	0.08	top1	1	0.08	4.2e-05	-5.8	-5.8	6.4e-09	0.75	0.33	0.30	FALSE
42	NAcc2	Plxnc1	gene expression	ENSRNOG00000007970	0.10	0.09	top1	1	0.09	1.5e-05	-5.4	-5.4	7.0e-08	0.80	0.60	0.06	FALSE
43	NAcc2	Mir331	gene expression	ENSRNOG00000035543	0.04	0.03	enet	75	0.04	2.6e-03	-5.2	5.4	6.6e-08	-0.67	0.60	0.27	FALSE
44	NAcc2	Tmcc3	isoform ratio	ENSRNOT00000102476	0.04	0.03	top1	1	0.03	7.9e-03	-5.8	-5.8	8.8e-09	0.80	0.10	0.04	FALSE
45	NAcc2	Tmcc3	intron excision ratio	chr7:29133627:29159418	0.06	0.07	top1	1	0.07	8.3e-05	-5.4	-5.4	8.2e-08	0.80	0.12	0.04	FALSE
46	NAcc2	Lta4h	mRNA stability	ENSRNOG00000004494	0.08	0.09	top1	1	0.09	1.0e-05	-5.2	5.2	2.1e-07	-0.60	0.18	0.12	FALSE
47	NAcc2	Vezt	mRNA stability	ENSRNOG00000006514	0.09	0.04	blup	2571	0.06	4.2e-04	-5.7	6.5	5.9e-11	-0.73	0.34	0.66	FALSE
48	OFC	Vezt	gene expression	ENSRNOG00000006514	0.38	0.25	enet	117	0.28	3.0e-07	-5.3	-5.5	4.8e-08	0.71	0.76	0.24	FALSE
49	OFC	Ndufa12	gene expression	ENSRNOG00000007407	0.19	0.16	top1	1	0.16	1.1e-04	-5.6	-5.6	2.7e-08	0.77	0.15	0.05	FALSE
50	OFC	Vezt	mRNA stability	ENSRNOG00000006514	0.24	0.12	blup	2568	0.14	3.2e-04	-5.6	6.3	3.2e-10	-0.76	0.58	0.39	FALSE
51	PL	Vezt	gene expression	ENSRNOG00000006514	0.26	0.17	top1	1	0.17	6.3e-05	-5.5	-5.5	3.9e-08	0.74	0.18	0.06	FALSE
52	PL	Vezt	mRNA stability	ENSRNOG00000006514	0.21	0.09	top1	1	0.09	3.2e-03	-5.2	5.2	1.8e-07	-0.77	0.13	0.05	FALSE
53	PL	Plxnc1	mRNA stability	ENSRNOG00000007970	0.38	0.14	lasso	7	0.18	4.3e-05	-2.8	5.3	1.5e-07	-0.70	0.64	0.31	FALSE
54	PL2	Vezt	gene expression	ENSRNOG00000006514	0.57	0.40	blup	2571	0.45	1.0e-26	-5.7	-6.1	8.0e-10	0.72	0.28	0.72	FALSE
55	PL2	Ndufa12	gene expression	ENSRNOG00000007407	0.09	0.06	blup	2574	0.07	7.5e-05	-5.2	-5.6	2.8e-08	0.77	0.78	0.21	FALSE
56	PL2	Socs2	gene expression	ENSRNOG00000008965	0.09	0.04	top1	1	0.04	3.6e-03	-5.8	5.8	8.2e-09	-0.74	0.13	0.04	FALSE
57	PL2	Fgd6	gene expression	ENSRNOG00000054515	0.08	0.05	blup	2571	0.05	9.5e-04	-5.4	-5.8	7.8e-09	0.79	0.77	0.22	FALSE
58	PL2	Cdk17	isoform ratio	ENSRNOT00000005762	0.26	0.12	blup	2990	0.15	9.4e-09	3.3	-5.2	2.3e-07	0.47	1.00	0.00	FALSE
59	PL2	Socs2	intron excision ratio	chr7:30015321:30041048	0.06	0.00	blup	3386	0.03	8.8e-03	-1.9	-5.5	3.7e-08	0.69	0.43	0.32	FALSE
60	PL2	Vezt	mRNA stability	ENSRNOG00000006514	0.30	0.40	lasso	7	0.42	2.2e-24	-5.4	6.0	1.5e-09	-0.79	0.78	0.22	FALSE
61	PL2	Plxnc1	mRNA stability	ENSRNOG00000007970	0.05	0.03	blup	3125	0.04	3.0e-03	-5.4	6.0	1.9e-09	-0.77	0.52	0.40	FALSE
62	PL2	Cradd	mRNA stability	ENSRNOG00000008507	0.08	0.01	blup	3492	0.04	1.9e-03	-5.8	6.1	1.1e-09	-0.71	0.37	0.54	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.