Best TWAS P=2.98483e-07 · Best GWAS P=1.111127e-08 conditioned to 0.01015635
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | PL | Dock1 | gene expression | ENSRNOG00000018683 | 0.26 | 0.03 | blup | 1965 | 0.08 | 0.0073 | -5.4 | 5.1 | 3e-07 | -0.85 | 0.19 | 0.63 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.