Hub : Traits : Tibia length in mm : ←

chr15:47,167,781-50,742,046

Best TWAS P=1.293207e-08 · Best GWAS P=9.174731e-09 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Esd	gene expression	ENSRNOG00000009512	0.17	0.11	top1	1	0.11	1.1e-12	5.4	5.4	6.3e-08	0.75	0.07	0.93	FALSE
2	Adipose	Rcbtb2	gene expression	ENSRNOG00000015054	0.11	0.06	top1	1	0.06	2.5e-07	5.4	5.4	5.6e-08	0.94	0.46	0.51	FALSE
3	Adipose	Lpar6	gene expression	ENSRNOG00000015577	0.07	0.05	enet	148	0.05	1.3e-06	5.7	5.5	4.6e-08	0.97	0.27	0.73	FALSE
4	Adipose	Med4	gene expression	ENSRNOG00000017170	0.03	0.02	top1	1	0.02	1.5e-03	5.4	5.4	8.3e-08	0.96	0.07	0.04	FALSE
5	Adipose	Nudt15	intron excision ratio	chr15:48711928:48713567	0.03	0.02	top1	1	0.02	6.5e-03	5.4	-5.4	8.4e-08	-0.96	0.06	0.03	FALSE
6	Adipose	Itm2b	mRNA stability	ENSRNOG00000016271	0.04	0.04	top1	1	0.04	1.5e-05	5.5	-5.5	3.7e-08	-0.88	0.21	0.34	FALSE
7	BLA	Fndc3a	gene expression	ENSRNOG00000014478	0.10	0.05	top1	1	0.05	1.6e-03	5.2	5.2	1.9e-07	0.89	0.09	0.05	FALSE
8	Brain	Nudt15	intron excision ratio	chr15:48711928:48713567	0.14	0.09	blup	2021	0.09	4.5e-09	5.2	-5.4	6.6e-08	-0.94	0.18	0.82	FALSE
9	Liver	Rcbtb2	intron excision ratio	chr15:48355011:48357257	0.10	0.08	top1	1	0.08	2.2e-09	5.7	5.7	1.3e-08	0.94	0.18	0.82	FALSE
10	Liver	Rcbtb2	intron excision ratio	chr15:48357396:48358748	0.03	0.02	top1	1	0.02	1.9e-03	5.4	5.4	8.1e-08	0.94	0.07	0.04	FALSE
11	Liver	Rcbtb2	intron excision ratio	chr15:48358397:48358748	0.20	0.21	top1	1	0.21	1.1e-22	5.4	-5.4	8.3e-08	-0.94	0.57	0.43	FALSE
12	Liver	Nudt15	intron excision ratio	chr15:48711928:48713567	0.07	0.05	blup	2019	0.06	3.7e-07	5.4	-5.5	3.1e-08	-0.94	0.33	0.67	FALSE
13	PL2	Nudt15	intron excision ratio	chr15:48711928:48713263	0.17	0.11	top1	1	0.11	1.2e-06	5.7	5.7	1.3e-08	0.97	0.15	0.77	TRUE
14	PL2	Nudt15	intron excision ratio	chr15:48711928:48713567	0.17	0.12	top1	1	0.12	2.9e-07	5.7	-5.7	1.3e-08	-0.97	0.15	0.79	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.