Best TWAS P=1.223517e-07 · Best GWAS P=1.132649e-06 conditioned to 0.3666234
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Slc4a10 | intron excision ratio | chr3:46868709:46874592 | 0.03 | 0.03 | enet | 21 | 0.04 | 2.4e-04 | -4.7 | 5.2 | 2.0e-07 | -0.47 | 0.42 | 0.48 | FALSE |
| 2 | NAcc | Slc4a10 | gene expression | ENSRNOG00000005307 | 0.11 | 0.07 | blup | 1243 | 0.11 | 1.2e-08 | -3.5 | 5.3 | 1.2e-07 | -0.82 | 0.44 | 0.56 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.