Best TWAS P=5.958017e-08 · Best GWAS P=6.907373e-07 conditioned to 0.03421345
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Dclk3 | gene expression | ENSRNOG00000033026 | 0.33 | 0.11 | enet | 129 | 0.16 | 4.0e-17 | -4.9 | -5.1 | 3.3e-07 | 0.89 | 0.42 | 0.58 | FALSE |
| 2 | Adipose | Als2cl | gene expression | ENSRNOG00000033921 | 0.29 | 0.03 | blup | 2705 | 0.03 | 1.6e-04 | -4.8 | 5.2 | 2.3e-07 | -0.89 | 0.52 | 0.46 | FALSE |
| 3 | PL | Cspg5 | gene expression | ENSRNOG00000020833 | 0.59 | 0.13 | enet | 341 | 0.14 | 4.6e-11 | -4.7 | -5.4 | 6.0e-08 | 0.60 | 0.52 | 0.48 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.