Hub : Traits : Tibia length : ← : →

chr7:26,575,816-30,853,534

Trait: Tibia length

Best TWAS P=1.61e-10 · Best GWAS P=9.65e-11 conditioned to 1.08e-02

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Nr2c1	alternative polyA	NM_145780.2	0.04	2761	0.03	3.4e-04	-5.46	4.86e-08	0.26	FALSE
Adipose	Nr2c1	alternative polyA	XM_039078458.1	0.04	2761	0.03	4.4e-04	5.41	6.42e-08	0.25	FALSE
Adipose	Ndufa12	gene expression	Ndufa12	0.31	161	0.21	1.5e-22	5.49	4.06e-08	0.12	FALSE
Adipose	Ube2n	gene expression	Ube2n	0.06	1	0.01	2.9e-02	5.39	7.05e-08	0.03	FALSE
Adipose	Vezt	gene expression	Vezt	0.11	1	0.1	8.4e-11	5.25	1.53e-07	0.04	FALSE
Adipose	Cep83	isoform ratio	XM_008765318.3	0.03	1	0.02	1.7e-03	-5.68	1.35e-08	0.03	FALSE
Adipose	Nr2c1	isoform ratio	XM_008765216.3	0.02	2761	0.01	2.0e-02	5.72	1.04e-08	0.2	FALSE
Adipose	Cep83	intron excision ratio	chr7_29322957_29325469	0.03	1	0.02	1.2e-03	5.99	2.12e-09	0.06	FALSE
Adipose	Nedd1	mRNA stability	Nedd1	0.06	2868	0.06	6.7e-07	-5.26	1.47e-07	0.52	FALSE
Adipose	Vezt	mRNA stability	Vezt	0.07	2620	0.09	3.0e-10	-6.27	3.72e-10	0.66	FALSE
BLA	Nr2c1	alternative polyA	NM_145780.2	0.08	2770	0.07	1.1e-04	-6.05	1.49e-09	0.51	FALSE
BLA	Nr2c1	alternative polyA	XM_039078458.1	0.08	2770	0.07	1.1e-04	6.07	1.32e-09	0.5	FALSE
BLA	Fgd6	gene expression	Fgd6	0.08	1	0.08	3.4e-05	5.75	8.74e-09	0.12	FALSE
BLA	Mir331	gene expression	Mir331	0.06	65	0.06	2.8e-04	-5.97	2.31e-09	0.28	FALSE
BLA	Ntn4	gene expression	Ntn4	0.06	2492	0.04	2.8e-03	5.88	4.16e-09	0.32	FALSE
BLA	Vezt	gene expression	Vezt	0.29	28	0.31	3.5e-17	-6.39	1.61e-10	0.4	TRUE
BLA	Nr2c1	isoform ratio	NM_145780.2	0.05	1	0.04	2.1e-03	5.42	5.93e-08	0.04	FALSE
BLA	Lta4h	intron excision ratio	chr7_27997602_27999743	0.06	1	0.03	7.6e-03	5.23	1.68e-07	0.04	FALSE
BLA	Plxnc1	mRNA stability	Plxnc1	0.09	1	0.08	7.2e-05	-5.23	1.70e-07	0.04	FALSE
BLA	Vezt	mRNA stability	Vezt	0.27	120	0.33	1.5e-18	6.16	7.40e-10	0.45	FALSE
Brain	Nr2c1	alternative polyA	NM_145780.2	0.05	72	0.06	6.6e-06	6.07	1.31e-09	0.23	FALSE
Brain	Nr2c1	alternative polyA	XM_039078458.1	0.05	1	0.06	2.8e-06	-5.42	5.82e-08	0.07	FALSE
Brain	Fgd6	alternative TSS	NM_001137645.1	0.04	1	0.04	3.3e-04	5.66	1.56e-08	0.19	FALSE
Brain	Fgd6	alternative TSS	XM_039079738.1	0.05	1	0.04	2.0e-04	-5.66	1.56e-08	0.21	FALSE
Brain	Fgd6	gene expression	Fgd6	0.17	1	0.2	6.5e-18	5.43	5.68e-08	0.1	FALSE
Brain	LOC120093556	gene expression	LOC120093556	0.05	2435	0.03	1.4e-03	-5.89	3.87e-09	0.7	FALSE
Brain	LOC120093563	gene expression	LOC120093563	0.05	4	0.03	1.2e-03	6.12	9.13e-10	0.83	FALSE
Brain	Ndufa12	gene expression	Ndufa12	0.42	2644	0.33	3.8e-31	-5.81	6.16e-09	0.12	FALSE
Brain	Vezt	gene expression	Vezt	0.2	2627	0.22	2.2e-20	-5.72	1.08e-08	0.18	FALSE
Brain	Lta4h	isoform ratio	NM_001030031.2	0.04	2339	0.01	1.4e-02	5.8	6.56e-09	0.49	FALSE
Brain	Lta4h	isoform ratio	XM_006241251.4	0.04	2339	0.01	1.6e-02	-5.78	7.68e-09	0.47	FALSE
Brain	Lta4h	intron excision ratio	chr7_27997602_27999743	0.05	1	0.03	1.3e-03	5.64	1.71e-08	0.28	FALSE
Brain	Vezt	intron excision ratio	chr7_28536176_28538306	0.04	2627	0.03	1.3e-03	5.49	4.12e-08	0.19	FALSE
Brain	Lta4h	mRNA stability	Lta4h	0.09	1	0.07	3.0e-07	-5.33	9.98e-08	0.6	FALSE
Brain	Vezt	mRNA stability	Vezt	0.08	57	0.07	4.3e-07	5.55	2.80e-08	0.28	FALSE
Eye	Fgd6	isoform ratio	NM_001137645.1	0.54	2617	0.13	4.7e-03	-6.03	1.68e-09	0.19	FALSE
IL	Vezt	gene expression	Vezt	0.31	2627	0.17	6.6e-05	-5.46	4.69e-08	0.28	FALSE
IL	Vezt	mRNA stability	Vezt	0.26	18	0.08	5.4e-03	-5.86	4.70e-09	0.22	FALSE
Liver	Nr2c1	alternative polyA	NM_145780.2	0.08	29	0.07	1.4e-08	5.54	3.11e-08	0.37	FALSE
Liver	Nr2c1	alternative polyA	XM_039078458.1	0.08	31	0.08	5.8e-09	-5.48	4.34e-08	0.36	FALSE
Liver	Amdhd1	gene expression	Amdhd1	0.38	267	0.37	1.6e-42	5.45	5.03e-08	0.51	FALSE
Liver	Ndufa12	gene expression	Ndufa12	0.41	2635	0.47	9.6e-58	-5.18	2.17e-07	0.12	FALSE
Liver	Ccdc38	isoform ratio	XM_039080094.1	0.24	2464	0.27	3.2e-30	-5.54	2.97e-08	0.55	FALSE
Liver	Ccdc38	isoform ratio	XM_039080095.1	0.05	2464	0.04	5.0e-05	5.86	4.66e-09	0.55	FALSE
Liver	Nr2c1	isoform ratio	NM_145780.2	0.09	15	0.09	1.0e-09	5.27	1.35e-07	0.27	FALSE
Liver	LOC102553539	intron excision ratio	chr7_27999133_27999512	0.13	2435	0.1	1.2e-11	5.3	1.15e-07	0.39	FALSE
Liver	LOC102553539	mRNA stability	LOC102553539	0.09	2435	0.06	2.8e-07	-5.23	1.73e-07	0.42	FALSE
Liver	Lta4h	mRNA stability	Lta4h	0.12	2336	0.09	3.1e-10	5.71	1.12e-08	0.41	FALSE
Liver	Snrpf	mRNA stability	Snrpf	0.03	1	0.01	1.1e-02	5.64	1.70e-08	0.06	FALSE
Liver	Tmcc3	mRNA stability	Tmcc3	0.03	2486	0.02	2.6e-03	-5.51	3.58e-08	0.24	FALSE
NAcc	Nr2c1	alternative polyA	NM_145780.2	0.05	1	0.04	7.1e-06	5.66	1.56e-08	0.18	FALSE
NAcc	Nr2c1	alternative polyA	XM_039078458.1	0.05	1	0.05	4.8e-06	-5.66	1.56e-08	0.2	FALSE
NAcc	Vezt	alternative polyA	XM_039078694.1	0.02	1	0.01	2.1e-02	-5.81	6.22e-09	0.05	FALSE
NAcc	Vezt	alternative polyA	XM_039078694.1	0.02	1	0.01	2.7e-02	-5.81	6.22e-09	0.05	FALSE
NAcc	Fgd6	gene expression	Fgd6	0.04	2617	0.02	8.1e-04	-6.15	7.88e-10	0.28	FALSE
NAcc	Lta4h	gene expression	Lta4h	0.04	2339	0.04	8.3e-06	5.78	7.39e-09	0.43	FALSE
NAcc	Mir331	gene expression	Mir331	0.03	2	0.02	6.8e-04	5.62	1.89e-08	0.1	FALSE
NAcc	Vezt	gene expression	Vezt	0.07	2617	0.12	2.9e-14	-6.22	5.09e-10	0.23	FALSE
NAcc	Plxnc1	isoform ratio	XM_039080099.1	0.02	3009	0.01	2.5e-02	5.59	2.21e-08	0.37	FALSE
NAcc	Vezt	mRNA stability	Vezt	0.12	16	0.2	3.0e-23	-5.97	2.31e-09	0.32	FALSE
OFC	Ndufa12	gene expression	Ndufa12	0.22	1	0.13	4.7e-04	5.58	2.34e-08	0.05	FALSE
OFC	Vezt	gene expression	Vezt	0.26	1	0.18	4.2e-05	5.33	9.98e-08	0.05	FALSE
OFC	Vezt	mRNA stability	Vezt	0.37	1	0.23	4.6e-06	5.39	7.05e-08	0.05	FALSE
PL	LOC102548848	alternative polyA	XR_005486848.1	0.16	3004	0.1	8.6e-11	5.57	2.48e-08	0	FALSE
PL	LOC102548848	alternative polyA	XR_355387.4	0.12	3004	0.07	3.7e-08	-5.58	2.43e-08	0.01	FALSE
PL	LOC102548848	alternative polyA	XR_005486848.1	0.18	3004	0.09	1.9e-10	5.32	1.03e-07	0	FALSE
PL	Nr2c1	alternative polyA	NM_145780.2	0.04	1	0.06	3.1e-07	5.5	3.91e-08	0.14	FALSE
PL	Nr2c1	alternative polyA	XM_039078458.1	0.05	1	0.06	2.8e-07	-5.5	3.91e-08	0.14	FALSE
PL	Fgd6	gene expression	Fgd6	0.06	1	0.08	3.0e-09	5.4	6.76e-08	0.09	FALSE
PL	Lta4h	gene expression	Lta4h	0.03	2339	0.01	3.5e-02	5.58	2.41e-08	0.49	FALSE
PL	Mir331	gene expression	Mir331	0.02	2415	0.03	6.2e-04	6.34	2.27e-10	0.64	FALSE
PL	Ndufa12	gene expression	Ndufa12	0.07	1	0.13	1.5e-14	5.66	1.56e-08	0.28	FALSE
PL	Vezt	gene expression	Vezt	0.26	22	0.36	2.7e-41	-6.25	4.18e-10	0.76	FALSE
PL	Plxnc1	mRNA stability	Plxnc1	0.04	1	0.03	4.5e-04	-5.61	2.07e-08	0.05	FALSE
PL	Vezt	mRNA stability	Vezt	0.16	21	0.22	2.5e-23	-5.74	9.67e-09	0.26	FALSE
pVTA	Fgd6	gene expression	Fgd6	0.05	1	0.03	2.7e-02	5.32	1.05e-07	0.04	FALSE
pVTA	Vezt	gene expression	Vezt	0.1	1	0.04	4.9e-03	5.68	1.34e-08	0.05	FALSE
pVTA	Lta4h	mRNA stability	Lta4h	0.18	2339	0.12	4.8e-06	5.55	2.87e-08	0.47	FALSE
RMTg	LOC102548848	isoform ratio	XR_355387.4	0.16	3004	0.08	3.7e-03	-5.67	1.39e-08	0.37	FALSE