Best TWAS P=2.6802e-07 · Best GWAS P=2.6802e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Prph | gene expression | ENSRNOG00000052880 | 0.09 | 0.07 | top1 | 1 | 0.07 | 5.7e-08 | 5.1 | -5.1 | 2.7e-07 | -0.95 | 0.09 | 0.91 | TRUE |
| 2 | Adipose | NA | gene expression | ENSRNOG00000067620 | 0.03 | 0.03 | top1 | 1 | 0.03 | 6.1e-04 | 5.1 | -5.1 | 2.7e-07 | -0.97 | 0.07 | 0.14 | FALSE |
| 3 | Adipose | NA | gene expression | ENSRNOG00000069732 | 0.02 | 0.01 | top1 | 1 | 0.01 | 4.3e-02 | 5.1 | 5.1 | 2.7e-07 | 0.97 | 0.04 | 0.04 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.