chr14:94,418,546-97,682,350

Trait: Tibia length

Best TWAS P=1.50e-08 · Best GWAS P=1.24e-07 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose LOC120096689 gene expression LOC120096689 0.42 2551 0.41 1.1e-48 -5.18 2.20e-07 0.81 FALSE
Adipose LOC120096689 isoform ratio XR_005493474.1 0.16 2551 0.13 7.6e-14 5.2 2.00e-07 0.85 FALSE
Adipose B3gnt2 mRNA stability B3gnt2 0.07 1414 0.06 6.4e-07 -5.58 2.43e-08 0.54 FALSE
BLA Tmem17 intron excision ratio chr14_96522291_96523082 0.09 1329 0.03 7.5e-03 5.42 5.99e-08 0.48 FALSE
Brain Commd1 isoform ratio XM_017599130.2 0.2 1 0.31 7.1e-29 5.27 1.36e-07 0.81 FALSE
Brain Tmem17 isoform ratio XM_039092230.1 0.1 1329 0.06 3.3e-06 -5.56 2.66e-08 0.65 TRUE
Brain B3gnt2 mRNA stability B3gnt2 0.06 1416 0.08 9.6e-08 5.21 1.86e-07 0.53 FALSE
IL Commd1 isoform ratio XM_017599130.2 0.26 29 0.16 9.5e-05 -5.28 1.32e-07 0.56 FALSE
IL LOC102552091 isoform ratio XR_005493490.1 0.17 1462 0.09 4.2e-03 5.23 1.66e-07 0.48 FALSE
LHb Tmem17 gene expression Tmem17 0.22 313 -0 3.8e-01 5.66 1.50e-08 0.13 TRUE
Liver B3gnt2 gene expression B3gnt2 0.05 1 0.09 1.4e-10 -5.22 1.82e-07 0.76 FALSE
PL LOC102552091 alternative polyA XR_005493486.1 0.02 1462 0.01 1.0e-02 5.19 2.13e-07 0.49 FALSE
PL LOC102552091 isoform ratio XR_005493490.1 0.04 1 0.04 5.9e-05 -5.29 1.24e-07 0.56 FALSE
PL Tmem17 isoform ratio XM_039092230.1 0.07 1 0.05 1.8e-06 5.21 1.93e-07 0.77 TRUE
pVTA Commd1 alternative TSS XM_017599129.2 0.22 1 0.22 5.8e-10 5.23 1.72e-07 0.77 FALSE
pVTA Commd1 alternative TSS NM_001115022.1 0.23 1 0.24 7.4e-11 -5.23 1.72e-07 0.77 FALSE
pVTA Commd1 alternative TSS XM_017599129.2 0.25 1 0.25 3.3e-11 5.23 1.72e-07 0.77 FALSE
pVTA Commd1 isoform ratio XM_017599130.2 0.24 8 0.27 5.2e-12 -5.19 2.12e-07 0.53 FALSE