Hub : Traits : Tibia length in mm : ← →

chr14:95,819,498-97,690,688

Best TWAS P=2.037706e-08 · Best GWAS P=1.238233e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	B3gnt2	isoform ratio	ENSRNOT00000097052	0.02	0.01	blup	1403	0.01	1.6e-02	5.0	5.5	4.0e-08	0.96	0.38	0.41	FALSE
2	Adipose	NA	isoform ratio	ENSRNOT00000012750	0.05	0.05	blup	1383	0.07	3.9e-08	5.0	-5.1	3.2e-07	-0.98	0.46	0.54	FALSE
3	Adipose	Zrsr1	isoform ratio	ENSRNOT00000012767	0.26	0.27	blup	1372	0.28	4.0e-31	5.1	5.1	3.2e-07	0.97	0.47	0.53	FALSE
4	Adipose	Zrsr1	intron excision ratio	chr14:96973368:96973445	0.05	0.06	blup	1372	0.06	1.9e-07	5.1	5.1	2.9e-07	0.98	0.46	0.54	FALSE
5	Adipose	Zrsr1	intron excision ratio	chr14:96973520:96973717	0.05	0.06	lasso	17	0.06	6.2e-07	5.0	-5.2	1.8e-07	0.83	0.45	0.55	TRUE
6	BLA	NA	alternative TSS	ENSRNOT00000120021	0.09	0.09	top1	1	0.09	1.8e-05	5.2	5.2	1.9e-07	0.96	0.13	0.32	FALSE
7	Brain	B3gnt2	gene expression	ENSRNOG00000009267	0.05	0.03	blup	1403	0.04	1.8e-04	5.0	-5.3	1.1e-07	-0.96	0.44	0.55	FALSE
8	Brain	NA	gene expression	ENSRNOG00000009281	0.07	0.09	blup	1383	0.11	1.7e-10	5.0	5.2	2.4e-07	0.96	0.42	0.58	FALSE
9	Brain	Zrsr1	intron excision ratio	chr14:96973520:96973757	0.02	0.01	blup	1372	0.01	3.1e-02	5.0	-5.1	2.8e-07	-0.97	0.38	0.44	FALSE
10	Brain	Zrsr1	intron excision ratio	chr14:96974116:96974197	0.21	0.14	top1	1	0.14	8.1e-13	5.2	-5.2	1.8e-07	-0.96	0.24	0.76	FALSE
11	Brain	Cct4	mRNA stability	ENSRNOG00000009642	0.03	0.01	blup	1399	0.01	1.5e-02	4.9	5.1	3.2e-07	0.98	0.41	0.53	FALSE
12	Liver	B3gnt2	alternative TSS	ENSRNOT00000118515	0.05	0.05	blup	1403	0.05	2.0e-06	4.9	-5.6	2.0e-08	-0.96	0.49	0.50	TRUE
13	Liver	Zrsr1	intron excision ratio	chr14:96973520:96973757	0.03	0.02	blup	1372	0.02	1.2e-03	5.0	5.1	2.6e-07	0.97	0.46	0.52	FALSE
14	NAcc2	NA	gene expression	ENSRNOG00000009281	0.18	0.13	blup	1383	0.18	7.8e-10	5.2	5.2	1.9e-07	0.97	0.43	0.57	FALSE
15	NAcc2	Tmem17	intron excision ratio	chr14:96522291:96523082	0.09	0.03	top1	1	0.03	1.0e-02	5.2	5.2	2.3e-07	0.94	0.06	0.05	FALSE
16	NAcc2	NA	intron excision ratio	chr14:96953354:96971850	0.20	0.15	lasso	9	0.17	1.4e-09	4.3	-5.1	2.9e-07	-0.91	0.44	0.56	TRUE
17	NAcc2	Zrsr1	intron excision ratio	chr14:96974076:96974157	0.07	0.03	blup	1372	0.04	2.2e-03	5.0	-5.1	3.0e-07	-0.98	0.47	0.51	FALSE
18	PL2	NA	isoform ratio	ENSRNOT00000012750	0.20	0.06	lasso	19	0.07	1.7e-04	4.9	-5.2	2.3e-07	-0.92	0.51	0.48	FALSE
19	PL2	NA	isoform ratio	ENSRNOT00000120021	0.17	0.05	lasso	15	0.05	1.2e-03	5.0	5.2	2.1e-07	0.95	0.49	0.49	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.