Best TWAS P=1.437443e-07 · Best GWAS P=1.219424e-07 conditioned to 6.226291e-07
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | IL | Eef1akmt2 | alternative polyA | ENSRNOT00000077956 | 0.30 | 0.08 | lasso | 3 | 0.09 | 0.0040 | -5.2 | -5.3 | 1.4e-07 | 0.63 | 0.28 | 0.60 | TRUE |
| 2 | IL | Eef1akmt2 | gene expression | ENSRNOG00000017137 | 0.17 | 0.11 | top1 | 1 | 0.11 | 0.0011 | -5.2 | 5.2 | 2.1e-07 | -0.91 | 0.07 | 0.07 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.