Best TWAS P=1.880276e-08 · Best GWAS P=0.03076338 conditioned to 4.869224e-07
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Rab2b | alternative polyA | ENSRNOT00000106538 | 0.07 | 0.04 | enet | 128 | 0.04 | 8.7e-06 | -1.2 | -5.6 | 1.9e-08 | 0.85 | 0.14 | 0.09 | TRUE |
| 2 | Adipose | Rab2b | alternative polyA | ENSRNOT00000115604 | 0.07 | 0.04 | enet | 112 | 0.05 | 7.3e-06 | -1.2 | 5.3 | 1.2e-07 | -0.84 | 0.14 | 0.09 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.