Best TWAS P=3.125341e-07 · Best GWAS P=3.412542e-07 conditioned to 1
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Brain | Slc26a11 | gene expression | ENSRNOG00000030537 | 0.27 | 0.3 | enet | 11 | 0.3 | 4.1e-28 | -4.9 | -5.1 | 3.1e-07 | 0.97 | 0.33 | 0.67 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.