Best TWAS P=1.69455e-07 · Best GWAS P=1.266973e-07 conditioned to 0.0003165116
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Cep112 | gene expression | ENSRNOG00000024557 | 0.11 | 0.09 | enet | 4 | 0.10 | 1.3e-09 | -5.0 | -5.2 | 2.2e-07 | -0.59 | 0.31 | 0.69 | TRUE |
| 2 | PL | Cep112 | gene expression | ENSRNOG00000024557 | 0.20 | 0.06 | top1 | 1 | 0.06 | 1.8e-02 | -5.2 | -5.2 | 1.7e-07 | 0.91 | 0.11 | 0.06 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.