chr10:87,148,755-89,011,911

Trait: Extensor digitorum longus weight

Best TWAS P=8.89e-08 · Best GWAS P=1.74e-07 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Acbd4 alternative polyA ENSRNOT00000004163 0.57 153 0.52 1.4e-67 5.22 1.76e-07 0.79 FALSE
Adipose Acbd4 alternative polyA ENSRNOT00000118852 0.59 213 0.51 1.3e-65 -5.18 2.23e-07 0.79 TRUE
Adipose Acbd4 gene expression ENSRNOG00000003108 0.77 252 0.66 4.8e-97 5.35 8.89e-08 0.79 TRUE
Adipose Acbd4 isoform ratio ENSRNOT00000004163 0.56 256 0.48 6.7e-61 5.28 1.29e-07 0.79 FALSE
Adipose Acbd4 isoform ratio ENSRNOT00000118852 0.57 241 0.5 2.0e-64 -5.24 1.57e-07 0.79 FALSE
Adipose Fmnl1 mRNA stability ENSRNOG00000003207 0.1 1 0.09 3.2e-10 -5.15 2.67e-07 0.77 FALSE
BLA Acbd4 alternative polyA ENSRNOT00000118852 0.32 229 0.27 7.6e-15 -5.16 2.43e-07 0 FALSE
Brain Acbd4 alternative polyA ENSRNOT00000004163 0.23 1 0.26 3.6e-24 5.1 3.38e-07 0.73 FALSE
Brain Acbd4 alternative polyA ENSRNOT00000118852 0.23 1 0.27 1.9e-25 -5.1 3.38e-07 0.73 FALSE
Brain Arhgap27 alternative TSS ENSRNOT00000038836 0.13 1 0.07 3.1e-07 5.15 2.67e-07 0.74 TRUE
Brain Arhgap27 alternative TSS ENSRNOT00000119071 0.12 1 0.07 5.0e-07 -5.17 2.33e-07 0.76 FALSE
IL Eftud2 gene expression ENSRNOG00000002818 0.38 1 0.32 1.8e-08 5.1 3.41e-07 0.48 FALSE
IL Gfap gene expression ENSRNOG00000002919 0.18 2 0.12 6.8e-04 -5.09 3.50e-07 0.45 TRUE
IL Acbd4 intron excision ratio chr10:88052617:88053211 0.24 3 0.15 2.0e-04 -5.1 3.41e-07 0.38 TRUE
LHb Acbd4 alternative polyA ENSRNOT00000004163 0.37 1 0.41 8.4e-11 5.1 3.41e-07 0.67 FALSE
LHb Acbd4 alternative polyA ENSRNOT00000118852 0.38 2 0.4 1.3e-10 -5.1 3.42e-07 0.76 FALSE
LHb Acbd4 isoform ratio ENSRNOT00000004163 0.39 1 0.28 3.0e-07 5.1 3.41e-07 0.43 FALSE
LHb Acbd4 isoform ratio ENSRNOT00000118852 0.35 1 0.26 6.5e-07 -5.1 3.41e-07 0.36 FALSE
Liver Acbd4 mRNA stability ENSRNOG00000003108 0.1 2232 0.07 1.1e-08 5.17 2.40e-07 0.67 FALSE
Liver Dcakd mRNA stability ENSRNOG00000021682 0.03 1 0.02 1.4e-03 5.14 2.69e-07 0.06 FALSE
NAcc Gfap gene expression ENSRNOG00000002919 0.08 1 0.08 1.5e-06 -5.15 2.67e-07 0.67 FALSE
NAcc Acbd4 intron excision ratio chr10:88050047:88050475 0.16 1 0.17 9.2e-13 -5.17 2.40e-07 0.79 FALSE
OFC Gfap gene expression ENSRNOG00000002919 0.28 4 0.19 2.7e-05 -5.18 2.24e-07 0.68 FALSE
OFC Acbd4 intron excision ratio chr10:88050047:88050282 0.27 1 0.14 3.5e-04 5.15 2.67e-07 0.08 FALSE
PL Gfap gene expression ENSRNOG00000002919 0.16 2103 0.12 2.5e-09 -5.15 2.58e-07 0.78 FALSE
PL Acbd4 gene expression ENSRNOG00000003108 0.17 1 0.16 2.1e-12 -5.15 2.67e-07 0.77 FALSE
PL Acbd4 intron excision ratio chr10:88050047:88050475 0.15 1 0.12 1.3e-09 -5.17 2.40e-07 0.79 FALSE
PL Dcakd mRNA stability ENSRNOG00000021682 0.09 1 0.07 6.1e-06 5.15 2.55e-07 0.57 FALSE