Hub : Traits : Extensor digitorum longus weight : ← : →

chr10:59,390,647-61,873,929

Trait: Extensor digitorum longus weight

Best TWAS P = 7.18e-08 · Best GWAS P= 5.92e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Slc43a2	alternative polyA	NM_001105812.1	0.03	1066	0.01	1.3e-02	-5.29	1.21e-07	0.6	FALSE
Adipose	Slc43a2	isoform ratio	NM_001105812.1	0.06	1066	0.03	6.0e-04	-5.31	1.10e-07	0.76	FALSE
Adipose	Myo1c	intron excision ratio	chr10_60997757_61003351	0.08	1	0.03	1.9e-04	-5.39	7.18e-08	0.35	TRUE
BLA	Inpp5k	gene expression	Inpp5k	0.22	1	0.17	3.8e-09	-5.29	1.19e-07	0.76	FALSE
BLA	Smyd4	intron excision ratio	chr10_60698680_60699761	0.08	22	0.05	9.6e-04	-5.32	1.01e-07	0.74	FALSE
BLA	Crk	mRNA stability	Crk	0.32	1213	0.28	1.9e-15	5.28	1.27e-07	0.84	FALSE
Brain	Slc43a2	alternative polyA	XM_063268681.1	0.06	37	0.04	8.8e-05	5.23	1.70e-07	0.67	FALSE
Brain	Crk	gene expression	Crk	0.33	14	0.26	2.8e-24	5.34	9.44e-08	0.82	FALSE
Brain	Pafah1b1	gene expression	Pafah1b1	0.03	1	0.02	3.2e-03	5.26	1.48e-07	0.1	TRUE
Brain	Rtn4rl1	gene expression	Rtn4rl1	0.3	1	0.18	1.4e-16	-5.3	1.13e-07	0.78	FALSE
Brain	Crk	mRNA stability	Crk	0.36	14	0.27	3.8e-25	5.32	1.04e-07	0.81	FALSE
Brain	Slc43a2	mRNA stability	Slc43a2	0.08	1	0.08	1.1e-07	5.3	1.16e-07	0.75	FALSE
IC	Doc2b	gene expression	Doc2b	0.4	173	0.26	3.0e-11	-5.29	1.24e-07	0.83	FALSE
IC	Crk	mRNA stability	Crk	0.39	1	0.3	3.2e-13	-5.33	9.59e-08	0.81	FALSE
IL	Crk	mRNA stability	Crk	0.2	1	0.11	1.5e-03	-5.25	1.50e-07	0.06	FALSE
Liver	Rpa1	gene expression	Rpa1	0.13	1	0.09	3.7e-10	-5.32	1.03e-07	0.78	FALSE
Liver	Smyd4	intron excision ratio	chr10_60698680_60699761	0.02	1	0.01	1.2e-02	5.23	1.70e-07	0.03	FALSE
Liver	Crk	mRNA stability	Crk	0.09	1	0.04	6.1e-05	-5.25	1.50e-07	0.5	FALSE
NAcc	Doc2b	gene expression	Doc2b	0.43	60	0.42	2.1e-68	5.37	8.00e-08	0.85	FALSE
NAcc	Mnt	gene expression	Mnt	0.13	1	0.08	4.7e-12	5.23	1.70e-07	0.81	FALSE
OFC	Doc2b	gene expression	Doc2b	0.41	1	0.08	6.1e-03	-5.23	1.72e-07	0.06	FALSE
OFC	Serpinf1	gene expression	Serpinf1	0.15	1	0.13	6.9e-04	5.23	1.72e-07	0.06	FALSE
PL	Crk	gene expression	Crk	0.22	8	0.21	3.1e-22	5.36	8.23e-08	0.82	FALSE
PL	Doc2b	gene expression	Doc2b	0.25	1	0.18	5.7e-19	-5.39	7.23e-08	0.86	FALSE
PL	Smyd4	isoform ratio	XM_063268677.1	0.04	1	0.04	3.6e-05	-5.23	1.72e-07	0.3	FALSE
pVTA	Crk	gene expression	Crk	0.18	1	0.17	7.8e-14	-5.25	1.50e-07	0.73	FALSE
pVTA	Doc2b	gene expression	Doc2b	0.17	80	0.06	1.9e-05	-5.36	8.45e-08	0.83	TRUE
pVTA	LOC102549294	gene expression	LOC102549294	0.04	6	0.03	2.8e-03	5.32	1.02e-07	0.65	TRUE
pVTA	Rpa1	gene expression	Rpa1	0.13	1	0.13	7.7e-11	5.33	9.59e-08	0.79	FALSE
RMTg	Crk	gene expression	Crk	0.18	13	0.12	5.1e-04	5.25	1.50e-07	0.61	FALSE