chr10:87,348,412-89,837,033

Trait: Extensor digitorum longus weight

Best TWAS P=7.89e-08 · Best GWAS P=1.74e-07 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Acbd4 alternative polyA XM_039086115.1 0.48 151 0.43 1.0e-51 -5.2 1.96e-07 0.78 FALSE
Adipose Acbd4 alternative polyA XM_039086115.1 0.48 137 0.43 7.1e-52 -5.21 1.84e-07 0.78 FALSE
Adipose Fmnl1 gene expression Fmnl1 0.22 1 0.18 6.7e-20 5.2 2.04e-07 0.81 FALSE
Adipose Fmnl1 mRNA stability Fmnl1 0.1 2223 0.08 2.1e-09 -5.18 2.17e-07 0.74 FALSE
BLA Mapt isoform ratio NM_017212.3 0.14 8 0.08 5.4e-05 -5.22 1.79e-07 0.65 FALSE
BLA Acbd4 intron excision ratio chr10_88050047_88050475 0.18 106 0.1 7.6e-06 5.37 7.89e-08 0.68 TRUE
Brain Plekhm1 alternative polyA XM_039086121.1 0.05 2274 0.01 1.9e-02 5.3 1.17e-07 0.54 FALSE
Brain Plekhm1 alternative polyA NM_001009677.2 0.04 2274 0.01 2.6e-02 -5.32 1.03e-07 0.55 FALSE
Brain Plekhm1 alternative polyA XM_039086121.1 0.04 2274 0.01 2.2e-02 5.32 1.02e-07 0.56 FALSE
Brain Plekhm1 isoform ratio NM_001009677.2 0.03 2274 0.01 1.8e-02 -5.27 1.34e-07 0.49 FALSE
LHb Acbd4 isoform ratio XM_006247509.4 0.45 207 0.24 2.4e-06 5.2 1.98e-07 0.73 FALSE
OFC Arhgap27 gene expression Arhgap27 0.15 2313 0.06 2.0e-02 -5.34 9.51e-08 0.34 FALSE