Project: dissection
2 significantly associated models · 2 unique genes
| # | chr | p0 | p1 | # assoc genes | # joint models | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 5 | 160021937 | 161464208 | 2 | 1 | 2.4e-08 | 2.8e-07 | 4e-55 | -826 | Rere |
p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.
| Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
|---|---|---|---|---|---|---|---|
| EDL weight in grams | 1.4 | 1 | 0 | 0 | 0 | 1 | Rere |
| tautz: manual_mpc3 | 3.4 | 1 | 0 | 0 | 0 | 1 | Eno1 |
| tautz: manual_spc8 | 5.4 | 1 | 0 | 0 | 0 | 1 | Eno1 |
| tautz: manual_spc2 | 4.2 | 1 | 0 | 0 | 0 | 1 | Eno1 |
| tautz: manual_spc13 | 4.0 | 1 | 0 | 0 | 0 | 1 | Rere |
| tautz: manual_spc1 | 6.7 | 1 | 0 | 0 | 0 | 1 | Eno1 |
| dd_expon_k | 5.2 | 1 | 0 | 0 | 0 | 1 | Eno1 |
| punishment | 5.7 | 1 | 0 | 0 | 0 | 1 | Rere |
chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.
| tissue | modality | # hits | % hits/tests | avg chisq |
|---|---|---|---|---|
| Adipose | alternative polyA | 0 | 0.000 | 1.4 |
| Adipose | alternative TSS | 0 | 0.000 | 1.4 |
| Adipose | gene expression | 0 | 0.000 | 1.4 |
| Adipose | isoform ratio | 0 | 0.000 | 1.4 |
| Adipose | intron excision ratio | 0 | 0.000 | 1.4 |
| Adipose | mRNA stability | 0 | 0.000 | 1.4 |
| BLA | alternative polyA | 0 | 0.000 | 1.4 |
| BLA | alternative TSS | 0 | 0.000 | 1.3 |
| BLA | gene expression | 0 | 0.000 | 1.4 |
| BLA | isoform ratio | 0 | 0.000 | 1.4 |
| BLA | intron excision ratio | 0 | 0.000 | 1.5 |
| BLA | mRNA stability | 0 | 0.000 | 1.4 |
| Brain | alternative polyA | 0 | 0.000 | 1.4 |
| Brain | alternative TSS | 0 | 0.000 | 1.5 |
| Brain | gene expression | 0 | 0.000 | 1.4 |
| Brain | isoform ratio | 0 | 0.000 | 1.4 |
| Brain | intron excision ratio | 0 | 0.000 | 1.4 |
| Brain | mRNA stability | 0 | 0.000 | 1.4 |
| Eye | alternative polyA | 0 | 0.000 | 1.3 |
| Eye | alternative TSS | 0 | 0.000 | 1.2 |
| Eye | gene expression | 0 | 0.000 | 1.4 |
| Eye | isoform ratio | 1 | 0.282 | 1.6 |
| Eye | intron excision ratio | 0 | 0.000 | 1.6 |
| Eye | mRNA stability | 0 | 0.000 | 1.4 |
| IL | alternative polyA | 0 | 0.000 | 1.4 |
| IL | alternative TSS | 0 | 0.000 | 1.5 |
| IL | gene expression | 0 | 0.000 | 1.4 |
| IL | isoform ratio | 0 | 0.000 | 1.4 |
| IL | intron excision ratio | 0 | 0.000 | 1.5 |
| IL | mRNA stability | 0 | 0.000 | 1.3 |
| LHb | alternative polyA | 0 | 0.000 | 1.3 |
| LHb | alternative TSS | 0 | 0.000 | 1.6 |
| LHb | gene expression | 0 | 0.000 | 1.4 |
| LHb | isoform ratio | 0 | 0.000 | 1.3 |
| LHb | intron excision ratio | 0 | 0.000 | 1.6 |
| LHb | mRNA stability | 0 | 0.000 | 1.4 |
| Liver | alternative polyA | 0 | 0.000 | 1.4 |
| Liver | alternative TSS | 0 | 0.000 | 1.5 |
| Liver | gene expression | 0 | 0.000 | 1.4 |
| Liver | isoform ratio | 0 | 0.000 | 1.5 |
| Liver | intron excision ratio | 0 | 0.000 | 1.5 |
| Liver | mRNA stability | 0 | 0.000 | 1.4 |
| NAcc | alternative polyA | 0 | 0.000 | 1.4 |
| NAcc | alternative TSS | 0 | 0.000 | 1.4 |
| NAcc | gene expression | 0 | 0.000 | 1.4 |
| NAcc | isoform ratio | 0 | 0.000 | 1.5 |
| NAcc | intron excision ratio | 0 | 0.000 | 1.5 |
| NAcc | mRNA stability | 0 | 0.000 | 1.4 |
| NAcc2 | alternative polyA | 0 | 0.000 | 1.6 |
| NAcc2 | alternative TSS | 0 | 0.000 | 1.3 |
| NAcc2 | gene expression | 0 | 0.000 | 1.4 |
| NAcc2 | isoform ratio | 0 | 0.000 | 1.5 |
| NAcc2 | intron excision ratio | 0 | 0.000 | 1.5 |
| NAcc2 | mRNA stability | 0 | 0.000 | 1.5 |
| OFC | alternative polyA | 0 | 0.000 | 1.4 |
| OFC | alternative TSS | 0 | 0.000 | 1.7 |
| OFC | gene expression | 0 | 0.000 | 1.4 |
| OFC | isoform ratio | 0 | 0.000 | 1.6 |
| OFC | intron excision ratio | 0 | 0.000 | 1.5 |
| OFC | mRNA stability | 0 | 0.000 | 1.4 |
| PL | alternative polyA | 0 | 0.000 | 1.6 |
| PL | alternative TSS | 0 | 0.000 | 1.6 |
| PL | gene expression | 0 | 0.000 | 1.4 |
| PL | isoform ratio | 0 | 0.000 | 1.4 |
| PL | intron excision ratio | 0 | 0.000 | 1.5 |
| PL | mRNA stability | 0 | 0.000 | 1.4 |
| PL2 | alternative polyA | 0 | 0.000 | 1.4 |
| PL2 | alternative TSS | 0 | 0.000 | 1.7 |
| PL2 | gene expression | 0 | 0.000 | 1.5 |
| PL2 | isoform ratio | 0 | 0.000 | 1.5 |
| PL2 | intron excision ratio | 0 | 0.000 | 1.5 |
| PL2 | mRNA stability | 1 | 0.041 | 1.4 |
avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.