Hub : Traits : Heart weight : ← : →

chr5:163,469,902-167,355,272

Trait: Heart weight

Best TWAS P = 5.91e-10 · Best GWAS P= 9.02e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	LOC134487042	gene expression	LOC134487042	0.02	2036	0	1.2e-01	5.21	1.89e-07	0.34	FALSE
BLA	Mtor	gene expression	Mtor	0.07	3	0.04	2.7e-03	-5.29	1.20e-07	0.58	FALSE
Brain	Tnfrsf9	gene expression	Tnfrsf9	0.74	2317	0.24	1.5e-22	-5.29	1.23e-07	0.46	TRUE
Brain	Casz1	intron excision ratio	chr5_164670614_164670865	0.12	47	0.07	8.7e-07	5.4	6.58e-08	0.52	TRUE
Brain	Tmem201	mRNA stability	Tmem201	0.04	34	0.04	4.7e-05	5.22	1.78e-07	0.36	TRUE
LHb	Nmnat1	intron excision ratio	chr5_165198986_165199288	0.19	1862	0.06	1.7e-02	5.23	1.66e-07	0.21	TRUE
LHb	Nmnat1	intron excision ratio	chr5_165198986_165200266	0.22	1862	0.09	3.2e-03	-5.32	1.05e-07	0.27	FALSE
Liver	Rbp7	gene expression	Rbp7	0.03	1815	0.01	3.0e-02	5.5	3.86e-08	0.3	FALSE
Liver	Masp2	intron excision ratio	chr5_164320359_164321967	0.13	1	0.13	8.1e-14	5.35	9.02e-08	0.95	FALSE
Liver	Rbp7	intron excision ratio	chr5_165170465_165170968	0.03	1815	0.01	1.2e-02	5.34	9.07e-08	0.23	FALSE
Liver	C5h1orf127	mRNA stability	C5h1orf127	0.02	1	0.01	9.2e-03	5.35	9.02e-08	0.1	FALSE
NAcc	Ctnnbip1	gene expression	Ctnnbip1	0.05	17	0.06	7.2e-09	6.19	5.91e-10	0.2	TRUE
OFC	Cenps	alternative polyA	XM_063287047.1	0.25	1	0.13	4.9e-04	-5.29	1.21e-07	0.08	TRUE
PL	Pik3cd	alternative TSS	XM_063288141.1	0.06	74	0.03	5.1e-04	5.29	1.25e-07	0.28	FALSE
PL	Casz1	intron excision ratio	chr5_164670614_164670865	0.06	69	0.03	4.0e-04	5.28	1.31e-07	0.32	FALSE
pVTA	Tnfrsf9	intron excision ratio	chr5_166679465_166680797	0.21	12	0.12	9.7e-10	5.24	1.59e-07	0.48	TRUE