Best TWAS P=9.94199e-11 · Best GWAS P=0.0405218 conditioned to 6.170024e-06
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Mat2b | intron excision ratio | chr10:25112547:25112951 | 0.57 | 0 | blup | 2091 | 0.09 | 6.6e-10 | 1.8 | -6.4 | 1.6e-10 | -0.77 | 0.06 | 0.03 | FALSE |
| 2 | Liver | Mat2b | intron excision ratio | chr10:25113065:25116692 | 0.61 | 0 | blup | 2091 | 0.10 | 4.0e-11 | 1.8 | 6.5 | 9.9e-11 | 0.77 | 0.06 | 0.04 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.