Best TWAS P=7.844029e-08 · Best GWAS P=1.987565e-09 conditioned to 0.001560827
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Adam12 | gene expression | ENSRNOG00000018384 | 0.12 | 0.01 | top1 | 1 | 0.01 | 7.6e-03 | 5.4 | -5.4 | 7.8e-08 | -0.69 | 0.03 | 0.58 | TRUE |
| 2 | BLA | Uros | mRNA stability | ENSRNOG00000017810 | 0.35 | 0.11 | lasso | 23 | 0.17 | 1.9e-09 | -4.6 | 5.2 | 2.3e-07 | 0.40 | 0.13 | 0.87 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.