chr10:105,295,338-107,195,627

Trait: Bone: cortical thickness

Best TWAS P=3.22e-12 · Best GWAS P=2.68e-10 conditioned to NaN

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose B3gntl1 alternative polyA XM_039086513.1 0.04 1087 0.01 3.0e-02 -5.87 4.36e-09 0.09 FALSE
Adipose B3gntl1 alternative polyA XM_039086513.1 0.04 1087 0.02 5.0e-03 -5.8 6.59e-09 0.05 TRUE
Adipose Dus1l alternative TSS XM_006247875.3 0.02 55 0.01 3.9e-02 -6.89 5.48e-12 0.01 FALSE
Adipose Dus1l alternative TSS NM_172018.2 0.02 8 0 1.1e-01 6.17 6.74e-10 0.01 FALSE
Adipose Dus1l alternative TSS XM_006247875.3 0.02 10 0 8.7e-02 -6.28 3.32e-10 0.01 TRUE
Adipose Wdr45b isoform ratio NM_001039587.1 0.12 1 0.07 2.2e-08 5.92 3.28e-09 0.8 FALSE
Adipose Wdr45b isoform ratio XM_039086445.1 0.04 1 0.01 2.4e-02 -5.92 3.28e-09 0.18 FALSE
BLA Sectm1a gene expression Sectm1a 0.13 1 0.1 3.9e-06 5.69 1.29e-08 0.26 TRUE
Brain Lrrc45 alternative TSS XM_039086852.1 0.15 49 0.05 2.3e-05 5.37 7.81e-08 0 TRUE
Brain Fn3k gene expression Fn3k 0.08 1 0.05 1.1e-05 -5.75 9.13e-09 0.54 FALSE
Eye Narf gene expression Narf 0.32 25 0.09 1.6e-02 -5.32 1.06e-07 0.38 FALSE
LHb B3gntl1 alternative TSS XM_039086520.1 0.38 36 0.11 1.3e-03 -6.81 9.80e-12 0.67 TRUE
OFC Rab40b gene expression Rab40b 0.33 11 0.06 1.8e-02 5.61 2.05e-08 0.67 TRUE
pVTA Foxk2 isoform ratio NM_001107075.1 0.29 1721 0.03 1.3e-02 -6.97 3.22e-12 0.46 TRUE