Best TWAS P=7.29e-08 · Best GWAS P=7.18e-08 conditioned to 8.94e-16
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Usp36 | gene expression | ENSRNOG00000028255 | 0.09 | 1 | 0.04 | 3.7e-05 | 5.36 | 8.42e-08 | 0.43 | FALSE |
| Adipose | Cep295nl | gene expression | ENSRNOG00000033143 | 0.25 | 194 | 0.22 | 6.9e-24 | -5.17 | 2.35e-07 | 0.04 | TRUE |
| Adipose | Cep295nl | isoform ratio | ENSRNOT00000004290 | 0.08 | 1 | 0.03 | 4.5e-04 | -5.31 | 1.09e-07 | 0.16 | FALSE |
| Adipose | C1qtnf1 | intron excision ratio | chr10:103675735:103678361 | 0.06 | 1 | 0.02 | 9.5e-04 | -5.36 | 8.19e-08 | 0.11 | FALSE |
| BLA | Cep295nl | gene expression | ENSRNOG00000033143 | 0.23 | 1 | 0.1 | 5.6e-06 | 5.31 | 1.11e-07 | 0.72 | FALSE |
| Brain | Cep295nl | gene expression | ENSRNOG00000033143 | 0.33 | 28 | 0.28 | 5.4e-26 | 5.25 | 1.53e-07 | 0.85 | FALSE |
| Brain | Cep295nl | intron excision ratio | chr10:103543287:103543754 | 0.1 | 1803 | 0.03 | 4.2e-04 | -5.27 | 1.35e-07 | 0.25 | FALSE |
| Brain | Usp36 | mRNA stability | ENSRNOG00000028255 | 0.08 | 1 | 0.03 | 4.1e-04 | -5.31 | 1.09e-07 | 0.3 | FALSE |
| IL | Cep295nl | gene expression | ENSRNOG00000033143 | 0.42 | 1 | 0.14 | 3.4e-04 | 5.31 | 1.09e-07 | 0.16 | FALSE |
| NAcc | Lgals3bp | gene expression | ENSRNOG00000003217 | 0.09 | 1 | 0.06 | 4.9e-05 | 5.38 | 7.33e-08 | 0.02 | TRUE |
| NAcc | Afmid | intron excision ratio | chr10:103056570:103056650 | 0.36 | 1 | 0.06 | 6.4e-05 | 5.38 | 7.29e-08 | 0.61 | TRUE |