Hub : Traits : Bone: cortical thickness : ← : →

chr10:95,109,047-99,430,546

Trait: Bone: cortical thickness

Best TWAS P = 2.18e-12 · Best GWAS P= 9.13e-12 conditioned to NaN

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Kcnj2	mRNA stability	Kcnj2	0.03	1	0.01	7.8e-03	-5.24	1.62e-07	0.03	FALSE
BLA	LOC102549521	gene expression	LOC102549521	0.18	17	0.06	4.8e-04	-6.1	1.04e-09	0.31	FALSE
Brain	LOC102549521	gene expression	LOC102549521	0.1	2431	0.09	7.3e-09	-5.67	1.44e-08	0	TRUE
Brain	LOC134480721	gene expression	LOC134480721	0.05	3495	0.07	6.7e-07	-5.22	1.77e-07	0.01	FALSE
Brain	Sox9	gene expression	Sox9	0.15	1	0.18	1.7e-16	-5.89	3.91e-09	0.01	FALSE
Brain	Abca5	mRNA stability	Abca5	0.05	2940	0.04	8.6e-05	-5.33	9.91e-08	0.1	TRUE
Brain	Sox9	mRNA stability	Sox9	0.03	1	0.02	1.1e-02	-5.79	7.19e-09	0.03	FALSE
Eye	LOC134480721	intron excision ratio	chr10_96977848_96984315	0.62	1	0.22	2.6e-04	-5.57	2.53e-08	0.05	TRUE
IC	LOC134480721	gene expression	LOC134480721	0.08	1	0.08	3.9e-04	-5.4	6.81e-08	0.04	FALSE
IL	LOC102549521	gene expression	LOC102549521	0.23	14	0.08	6.7e-03	-5.72	1.08e-08	0.03	FALSE
IL	LOC102549836	gene expression	LOC102549836	0.5	16	0.18	3.4e-05	-5.25	1.52e-07	0.09	FALSE
LHb	LOC102549521	gene expression	LOC102549521	0.56	8	0.22	7.1e-06	-6.04	1.53e-09	0.06	TRUE
LHb	LOC102549836	gene expression	LOC102549836	0.39	7	0.04	4.8e-02	-7.02	2.18e-12	0.83	TRUE
LHb	LOC134480721	gene expression	LOC134480721	0.23	9	0.2	2.1e-05	-5.73	9.82e-09	0.08	FALSE
LHb	LOC134480722	gene expression	LOC134480722	0.31	2914	0.17	8.4e-05	5.98	2.17e-09	0.16	TRUE
NAcc	LOC102549521	gene expression	LOC102549521	0.19	33	0.14	3.5e-21	-5.61	2.04e-08	0	FALSE
NAcc	LOC102549596	gene expression	LOC102549596	0.07	2382	0.08	1.5e-11	-5.48	4.33e-08	0	FALSE
OFC	LOC102549521	gene expression	LOC102549521	0.17	1	0.11	1.2e-03	-5.82	5.74e-09	0.05	TRUE
OFC	Map2k6	gene expression	Map2k6	0.42	2887	0.31	5.4e-08	5.45	5.11e-08	0.2	FALSE
PL	Sox9	gene expression	Sox9	0.18	147	0.19	7.1e-20	-5.68	1.31e-08	0.01	FALSE
pVTA	Kcnj16	alternative polyA	NM_053314.3	0.04	2850	0.05	1.1e-04	-5.28	1.27e-07	0.27	FALSE
pVTA	Sox9	gene expression	Sox9	0.15	1	0.15	5.0e-12	-5.66	1.52e-08	0	FALSE