Hub : Traits : Bone: cortical thickness : →

chr3:126,323,673-128,419,948

Trait: Bone: cortical thickness

Best TWAS P=5.13e-09 · Best GWAS P=5.49e-09 conditioned to 1.68e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ndufaf5	gene expression	ENSRNOG00000004784	0.04	1	0.02	4.1e-03	5.46	4.79e-08	0.04	FALSE
Adipose	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.12	1	0.07	5.6e-08	5.74	9.36e-09	0.84	FALSE
Adipose	Esf1	mRNA stability	ENSRNOG00000004777	0.17	1671	0.07	2.9e-08	5.76	8.40e-09	0.82	FALSE
Adipose	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.04	54	0.01	1.5e-02	5.11	3.29e-07	0.36	FALSE
BLA	Esf1	gene expression	ENSRNOG00000004777	0.66	33	0.37	6.9e-21	-5.82	6.02e-09	0.83	FALSE
BLA	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.8	162	0.44	6.0e-26	5.84	5.13e-09	0.83	TRUE
BLA	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.79	169	0.44	7.1e-26	-5.81	6.16e-09	0.83	FALSE
BLA	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.6	17	0.22	8.0e-12	5.75	8.92e-09	0.82	FALSE
Brain	Esf1	gene expression	ENSRNOG00000004777	0.69	101	0.53	7.6e-58	-5.71	1.14e-08	0.82	FALSE
Brain	Esf1	intron excision ratio	chr3:127505805:127507637	0.1	1	0.06	2.9e-06	-5.75	9.13e-09	0.81	FALSE
Brain	Esf1	intron excision ratio	chr3:127505805:127507789	0.17	1	0.09	6.1e-09	5.75	9.13e-09	0.84	FALSE
Brain	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.71	28	0.49	3.6e-51	5.69	1.30e-08	0.82	FALSE
Brain	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.71	45	0.49	8.0e-51	-5.69	1.31e-08	0.82	FALSE
Brain	Ndufaf5	intron excision ratio	chr3:127526933:127536740	0.07	1	0.03	1.2e-03	5.75	9.13e-09	0.19	FALSE
Brain	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.09	1	0.04	5.0e-05	5.71	1.15e-08	0.65	FALSE
IL	Esf1	gene expression	ENSRNOG00000004777	0.66	1	0.28	2.2e-07	-5.4	6.65e-08	0.16	FALSE
IL	Tasp1	intron excision ratio	chr3:127355890:127385049	0.25	9	0.06	1.6e-02	-5.83	5.39e-09	0.56	FALSE
IL	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.41	4	0.09	3.4e-03	5.3	1.13e-07	0.69	FALSE
IL	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.42	1	0.15	2.2e-04	-5.71	1.13e-08	0.1	FALSE
LHb	Esf1	gene expression	ENSRNOG00000004777	0.7	1	0.5	9.3e-14	-5.71	1.15e-08	0.81	FALSE
LHb	Ism1	gene expression	ENSRNOG00000063262	0.48	23	0.47	9.7e-13	-5.79	7.15e-09	0.67	FALSE
LHb	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.43	14	0.24	1.9e-06	5.55	2.93e-08	0.76	FALSE
LHb	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.42	4	0.24	2.5e-06	-5.5	3.90e-08	0.77	FALSE
Liver	Esf1	gene expression	ENSRNOG00000004777	0.09	16	0.04	1.2e-05	5.8	6.78e-09	0.82	FALSE
Liver	Ndufaf5	gene expression	ENSRNOG00000004784	0.17	21	0.1	1.1e-10	5.79	7.21e-09	0.81	FALSE
NAcc	Esf1	gene expression	ENSRNOG00000004777	0.47	504	0.32	3.7e-24	-5.64	1.68e-08	0.83	FALSE
NAcc	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.59	19	0.45	1.4e-36	5.72	1.05e-08	0.83	FALSE
NAcc	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.59	33	0.44	5.3e-36	-5.73	9.76e-09	0.83	FALSE
NAcc	AABR07054000.1	intron excision ratio	chr3:127747955:127748961	0.07	1	0.03	2.0e-03	-5.66	1.49e-08	0.1	FALSE
NAcc	AABR07054000.1	intron excision ratio	chr3:127747955:127749007	0.07	1	0.03	1.7e-03	5.66	1.49e-08	0.11	FALSE
NAcc	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.1	36	0.07	6.6e-06	5.46	4.80e-08	0.64	FALSE
OFC	Esf1	gene expression	ENSRNOG00000004777	0.65	1	0.39	3.8e-10	-5.66	1.52e-08	0.71	FALSE
OFC	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.58	1669	0.23	4.6e-06	5.78	7.58e-09	0.81	FALSE
OFC	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.61	1669	0.24	1.6e-06	-5.81	6.34e-09	0.81	FALSE
PL	Tasp1	gene expression	ENSRNOG00000004493	0.04	8	0.02	1.0e-02	-5.4	6.59e-08	0.35	FALSE
PL	Esf1	gene expression	ENSRNOG00000004777	0.47	31	0.33	5.5e-26	-5.72	1.06e-08	0.83	FALSE
PL	Ndufaf5	gene expression	ENSRNOG00000004784	0.16	24	0.08	5.9e-07	5.64	1.68e-08	0.81	FALSE
PL	Tasp1	isoform ratio	ENSRNOT00000055630	0.05	1	0.04	3.5e-04	-5.4	6.73e-08	0.04	FALSE
PL	Esf1	intron excision ratio	chr3:127505805:127507789	0.07	1	0.05	2.1e-04	5.75	9.13e-09	0.19	FALSE
PL	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.84	1	0.45	5.3e-37	5.72	1.05e-08	0.82	FALSE
PL	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.86	1	0.44	2.0e-36	-5.72	1.05e-08	0.82	FALSE
PL	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.18	50	0.13	4.7e-10	5.62	1.91e-08	0.82	FALSE