Best TWAS P=3.468118e-09 · Best GWAS P=2.012552e-10 conditioned to 0.003293728
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Sox9 | gene expression | ENSRNOG00000002607 | 0.34 | 0.30 | enet | 46 | 0.32 | 7.3e-18 | 5.9 | -5.7 | 9.3e-09 | -0.73 | 0.90 | 0.10 | FALSE |
| 2 | Brain | Sox9 | gene expression | ENSRNOG00000002607 | 0.15 | 0.19 | top1 | 1 | 0.19 | 4.6e-17 | 5.9 | -5.9 | 3.5e-09 | -0.74 | 0.81 | 0.18 | TRUE |
| 3 | Brain | Sox9 | mRNA stability | ENSRNOG00000002607 | 0.03 | 0.03 | top1 | 1 | 0.03 | 1.9e-03 | 5.5 | -5.5 | 3.8e-08 | -0.71 | 0.10 | 0.03 | FALSE |
| 4 | PL | Sox9 | gene expression | ENSRNOG00000002607 | 0.18 | 0.12 | blup | 2665 | 0.13 | 9.1e-10 | 5.8 | -5.3 | 1.4e-07 | -0.54 | 0.92 | 0.08 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.