Best TWAS P=1.65e-08 · Best GWAS P=7.78e-11 conditioned to 2.56e-06
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | LOC120095206 | gene expression | LOC120095206 | 0.03 | 1 | 0.01 | 3.4e-02 | 5.47 | 4.40e-08 | 0.09 | FALSE |
| Brain | Abca5 | mRNA stability | Abca5 | 0.05 | 2874 | 0.05 | 1.5e-05 | -5.39 | 7.10e-08 | 0.05 | FALSE |
| OFC | Abca5 | gene expression | Abca5 | 0.26 | 156 | 0.15 | 2.5e-04 | -5.46 | 4.80e-08 | 0.4 | FALSE |
| OFC | Map2k6 | gene expression | Map2k6 | 0.42 | 2818 | 0.29 | 1.0e-07 | 5.65 | 1.65e-08 | 0.32 | TRUE |
| pVTA | Kcnj16 | alternative polyA | NM_053314.3 | 0.08 | 2778 | 0.06 | 1.3e-03 | -5.27 | 1.38e-07 | 0.23 | FALSE |
| pVTA | Kcnj16 | alternative TSS | NM_053314.3 | 0.27 | 2778 | 0.33 | 6.3e-15 | -5.19 | 2.12e-07 | 0.16 | FALSE |
| pVTA | Kcnj16 | alternative TSS | XM_006247570.3 | 0.27 | 2778 | 0.34 | 1.3e-15 | 5.18 | 2.19e-07 | 0.17 | FALSE |
| pVTA | Kcnj16 | gene expression | Kcnj16 | 0.28 | 117 | 0.37 | 3.3e-17 | 5.27 | 1.37e-07 | 0.22 | FALSE |