Best TWAS P=1.399563e-07 · Best GWAS P=1.387513e-06 conditioned to 0.1040828
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Brain | Nol11 | mRNA stability | ENSRNOG00000052934 | 0.08 | 0.01 | enet | 36 | 0.03 | 0.00037 | 2.3 | -5.3 | 1.4e-07 | -0.69 | 0.53 | 0.32 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.