Best TWAS P=3.197436e-08 · Best GWAS P=0.002307689 conditioned to 0.05547816
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Dhcr7 | gene expression | ENSRNOG00000020776 | 0.25 | 0.01 | enet | 91 | 0.04 | 8.9e-05 | 1.5 | 5.5 | 3.2e-08 | 0.21 | 0.06 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.