Hub : Traits : Extensor digitorum longus weight : ←

chr15:47,167,781-49,440,043

Trait: Extensor digitorum longus weight

Best TWAS P=2.06e-11 · Best GWAS P=7.82e-13 conditioned to 4.11e-03

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Fndc3a	alternative TSS	ENSRNOT00000101367	0.05	2041	0.04	2.7e-05	6.49	8.66e-11	0.3	FALSE
Adipose	Fndc3a	alternative TSS	ENSRNOT00000111875	0.05	2041	0.03	1.4e-04	-6.5	7.87e-11	0.42	FALSE
Adipose	Fndc3a	alternative TSS	ENSRNOT00000101367	0.06	2041	0.04	2.1e-05	6.46	1.03e-10	0.26	FALSE
Adipose	Fndc3a	alternative TSS	ENSRNOT00000111875	0.05	2041	0.03	1.0e-04	-6.49	8.83e-11	0.39	FALSE
Adipose	Itm2b	gene expression	ENSRNOG00000016271	0.1	1980	0.1	3.3e-11	5.34	9.05e-08	0.58	FALSE
Adipose	Fndc3a	intron excision ratio	chr15:47755611:47801368	0.04	1	0.03	8.4e-04	-5.4	6.69e-08	0.03	FALSE
Adipose	Fndc3a	intron excision ratio	chr15:47832616:47866529	0.03	6	0.01	1.2e-02	-6.7	2.06e-11	0.1	TRUE
Adipose	Rcbtb2	intron excision ratio	chr15:48333445:48336229	0.15	2077	0.15	2.4e-16	5.24	1.63e-07	0.58	FALSE
Adipose	Rb1	mRNA stability	ENSRNOG00000016029	0.09	1	0.08	1.3e-09	5.36	8.33e-08	0.64	FALSE
BLA	Itm2b	gene expression	ENSRNOG00000016271	0.24	1	0.12	3.7e-07	5.21	1.88e-07	0.44	FALSE
BLA	Nudt15	gene expression	ENSRNOG00000025239	0.07	1	0.04	2.2e-03	-5.2	2.02e-07	0.05	FALSE
BLA	Rb1	mRNA stability	ENSRNOG00000016029	0.1	1	0.07	1.5e-04	-5.38	7.42e-08	0.06	FALSE
Brain	Fndc3a	gene expression	ENSRNOG00000014478	0.05	2041	0.01	2.7e-02	-5.84	5.10e-09	0.15	FALSE
Brain	Med4	gene expression	ENSRNOG00000017170	0.08	1	0.1	1.9e-09	-5.39	6.92e-08	0.77	FALSE
Brain	Nudt15	gene expression	ENSRNOG00000025239	0.12	1	0.13	1.7e-12	-5.11	3.19e-07	0.46	FALSE
Brain	Itm2b	mRNA stability	ENSRNOG00000016271	0.1	3	0.07	1.1e-06	-5.43	5.52e-08	0.46	FALSE
IL	Rb1	gene expression	ENSRNOG00000016029	0.19	1	0.05	2.6e-02	-5.14	2.76e-07	0.05	FALSE
IL	Itm2b	gene expression	ENSRNOG00000016271	0.43	1	0.26	6.5e-07	5.18	2.20e-07	0.18	FALSE
Liver	Rcbtb2	mRNA stability	ENSRNOG00000015054	0.26	2077	0.26	3.7e-28	-5.45	5.04e-08	0.63	FALSE
NAcc	Itm2b	gene expression	ENSRNOG00000016271	0.31	1	0.13	6.4e-10	5.24	1.58e-07	0.51	FALSE
NAcc	Cysltr2	isoform ratio	ENSRNOT00000105845	0.05	2076	0	1.4e-01	-5.54	3.01e-08	0.45	FALSE
OFC	Rb1	gene expression	ENSRNOG00000016029	0.18	1	0.1	2.6e-03	-5.4	6.69e-08	0.06	FALSE
OFC	Itm2b	gene expression	ENSRNOG00000016271	0.18	1	0.08	6.0e-03	5.19	2.11e-07	0.05	FALSE
PL	Fndc3a	gene expression	ENSRNOG00000014478	0.04	2040	0	1.4e-01	-6.41	1.43e-10	0.32	FALSE
PL	Nudt15	gene expression	ENSRNOG00000025239	0.05	1	0.03	1.5e-03	-5.31	1.12e-07	0.12	FALSE