Hub : Traits : Light reinforcement 2 : ← →

chr1:140,614,300-142,727,457

Trait: Light reinforcement 2

Best TWAS P=3.236491e-09 · Best GWAS P=1.237561e-09 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Ctsc	isoform ratio	ENSRNOT00000022342	0.16	0.10	blup	2515	0.16	4.3e-17	3.9	5.1	2.7e-07	-0.87	0.74	0.26	FALSE
2	Adipose	Ctsc	isoform ratio	ENSRNOT00000097085	0.18	0.11	blup	2515	0.18	1.3e-19	-5.7	-5.2	1.9e-07	0.89	0.45	0.55	FALSE
3	Adipose	Ctsc	intron excision ratio	chr1:142031177:142036233	0.05	0.03	blup	2515	0.04	6.5e-05	-5.6	-5.2	1.8e-07	0.91	0.43	0.56	FALSE
4	Adipose	Ctsc	intron excision ratio	chr1:142031177:142045569	0.04	0.01	blup	2515	0.02	4.7e-03	-5.6	5.1	3.3e-07	-0.88	0.55	0.42	FALSE
5	BLA	Ctsc	mRNA stability	ENSRNOG00000016496	0.05	0.03	top1	1	0.03	1.5e-02	-5.8	5.8	5.9e-09	-0.89	0.10	0.05	FALSE
6	Brain	Grm5	gene expression	ENSRNOG00000016429	0.16	0.10	lasso	6	0.15	5.3e-14	-5.7	5.3	9.0e-08	-0.84	0.32	0.68	FALSE
7	Brain	Ctsc	isoform ratio	ENSRNOT00000022342	0.03	0.04	top1	1	0.04	1.7e-04	-5.9	5.9	3.3e-09	-0.89	0.09	0.28	FALSE
8	Eye	Ctsc	gene expression	ENSRNOG00000016496	0.29	0.15	top1	1	0.15	2.9e-03	-5.6	-5.6	2.1e-08	0.92	0.14	0.06	FALSE
9	IL	Ctsc	gene expression	ENSRNOG00000016496	0.30	0.16	top1	1	0.16	1.0e-04	-5.7	-5.7	1.6e-08	0.91	0.13	0.07	FALSE
10	NAcc	Ctsc	gene expression	ENSRNOG00000016496	0.12	0.09	blup	2516	0.12	3.3e-09	-5.6	-5.3	1.4e-07	0.92	0.43	0.57	FALSE
11	PL	Grm5	mRNA stability	ENSRNOG00000016429	0.04	0.03	top1	1	0.03	1.3e-03	-5.9	-5.9	3.2e-09	0.93	0.09	0.07	TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.