Hub : Traits : Light reinforcement 2 : →

chr1:140,610,199-142,727,457

Trait: Light reinforcement 2

Best TWAS P=4.54e-09 · Best GWAS P=1.24e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ctsc	intron excision ratio	chr1_142031177_142036233	0.05	2521	0.02	1.1e-03	-5.3	1.17e-07	0.6	FALSE
Adipose	Ctsc	intron excision ratio	chr1_142031177_142045569	0.04	2521	0.03	4.0e-04	5.24	1.58e-07	0.52	FALSE
BLA	Ctsc	gene expression	Ctsc	0.1	1	0.08	7.2e-05	5.86	4.54e-09	0.34	TRUE
BLA	Ctsc	isoform ratio	XM_008759637.3	0.05	1	0.03	1.2e-02	5.27	1.40e-07	0.04	FALSE
BLA	Grm5	isoform ratio	XM_017588780.2	0.06	2702	0.01	6.6e-02	5.48	4.37e-08	0.51	FALSE
Brain	Ctsc	alternative polyA	NM_017097.2	0.06	1	0.07	5.1e-07	-5.27	1.40e-07	0.15	FALSE
Brain	Ctsc	alternative polyA	XM_008759637.3	0.06	1	0.07	2.3e-07	5.75	8.96e-09	0.71	FALSE
Brain	Grm5	gene expression	Grm5	0.55	26	0.32	1.9e-30	-5.38	7.43e-08	0.67	FALSE
Brain	Ctsc	isoform ratio	NM_017097.2	0.06	1	0.06	4.1e-06	-5.66	1.50e-08	0.55	FALSE
Brain	Ctsc	isoform ratio	XM_008759637.3	0.06	1	0.06	1.2e-06	5.66	1.50e-08	0.58	FALSE
Brain	Grm5	isoform ratio	XM_017588780.2	0.05	93	0.04	2.2e-04	-5.29	1.22e-07	0.57	FALSE
Brain	Grm5	mRNA stability	Grm5	0.11	1	0.09	4.7e-09	-5.76	8.52e-09	0.68	FALSE
Eye	Ctsc	gene expression	Ctsc	0.37	2521	0.14	3.3e-03	-5.45	5.17e-08	0.32	FALSE
IL	Ctsc	gene expression	Ctsc	0.48	10	0.14	2.9e-04	-5.78	7.46e-09	0.54	FALSE
Liver	LOC102554680	gene expression	LOC102554680	0.04	2516	0.03	5.3e-04	-5.72	1.04e-08	0.65	FALSE
NAcc	Ctsc	gene expression	Ctsc	0.14	2521	0.16	1.5e-18	-5.37	7.68e-08	0.6	FALSE
NAcc	Grm5	gene expression	Grm5	0.05	1	0.05	1.4e-06	-5.65	1.64e-08	0.47	FALSE
NAcc	Grm5	isoform ratio	XM_017588780.2	0.04	2702	0.03	1.1e-04	5.82	5.73e-09	0.67	FALSE
PL	Grm5	gene expression	Grm5	0.03	23	0.03	1.2e-04	5.52	3.48e-08	0.22	FALSE