Hub : Traits : Light reinforcement 2 : →

chr1:149,923,636-152,140,050

Trait: Light reinforcement 2

Best TWAS P = 3.92e-09 · Best GWAS P= 2.60e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Brain	Ctsc	alternative polyA	NM_017097.2	0.06	24	0.07	6.4e-07	5.23	1.74e-07	0.64	FALSE
Brain	Ctsc	alternative polyA	XM_008759637.4	0.06	24	0.07	6.5e-07	-5.24	1.58e-07	0.63	FALSE
Brain	Grm5	gene expression	Grm5	0.46	13	0.3	2.5e-28	5.39	6.86e-08	0.74	FALSE
Brain	Ctsc	isoform ratio	NM_017097.2	0.06	1	0.05	2.1e-05	5.5	3.77e-08	0.48	FALSE
Brain	Ctsc	isoform ratio	XM_008759637.4	0.06	1	0.05	2.6e-05	-5.5	3.77e-08	0.47	FALSE
Brain	Grm5	mRNA stability	Grm5	0.1	1	0.09	4.9e-09	5.58	2.35e-08	0.63	FALSE
IC	Ctsc	alternative polyA	NM_017097.2	0.09	1	0.06	1.6e-03	5.24	1.57e-07	0.04	FALSE
IC	Ctsc	alternative polyA	XM_008759637.4	0.08	1	0.05	2.6e-03	-5.24	1.57e-07	0.04	FALSE
IL	Ctsc	gene expression	Ctsc	0.44	19	0.11	1.4e-03	-5.89	3.92e-09	0.58	TRUE
Liver	LOC102554680	gene expression	LOC102554680	0.05	13	0.04	7.2e-05	-5.26	1.42e-07	0.65	FALSE
NAcc	Grm5	gene expression	Grm5	0.08	1	0.08	7.3e-12	5.52	3.39e-08	0.55	FALSE
NAcc	Tyr	gene expression	Tyr	0.02	2904	0.01	1.3e-02	5.23	1.67e-07	0.43	FALSE
NAcc	Grm5	mRNA stability	Grm5	0.03	1	0.03	3.3e-05	5.52	3.39e-08	0.28	FALSE
OFC	Grm5	gene expression	Grm5	0.23	11	0.16	1.0e-04	5.33	9.60e-08	0.44	FALSE