chr1:140,614,300-142,727,457

Trait: Delay discounting water rate 18 sec

Best TWAS P=1.95e-10 · Best GWAS P=3.55e-09 conditioned to 3.56e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
BLA Ctsc alternative polyA ENSRNOT00000022342 0.07 2518 0.01 5.1e-02 -6.35 2.13e-10 0.22 FALSE
BLA Ctsc alternative polyA ENSRNOT00000097085 0.07 2518 0.02 3.2e-02 6.27 3.53e-10 0.19 FALSE
BLA Ctsc gene expression ENSRNOG00000016496 0.12 1 0.1 5.0e-06 5.63 1.78e-08 0.35 FALSE
BLA Ctsc mRNA stability ENSRNOG00000016496 0.05 1 0.03 1.5e-02 -5.62 1.93e-08 0.04 FALSE
Brain Grm5 gene expression ENSRNOG00000016429 0.16 6 0.15 5.3e-14 -6.37 1.95e-10 0.7 TRUE
Brain Ctsc isoform ratio ENSRNOT00000022342 0.03 1 0.04 1.7e-04 -5.9 3.55e-09 0.32 FALSE
Eye Ctsc gene expression ENSRNOG00000016496 0.29 1 0.15 2.9e-03 5.57 2.52e-08 0.06 FALSE
IL Ctsc gene expression ENSRNOG00000016496 0.3 1 0.16 1.0e-04 5.59 2.31e-08 0.07 FALSE
PL Grm5 mRNA stability ENSRNOG00000016429 0.04 1 0.03 1.3e-03 5.65 1.62e-08 0.06 FALSE