Best TWAS P=3.392948e-07 · Best GWAS P=2.579018e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Map4k4 | intron excision ratio | chr9:42307381:42308186 | 0.07 | 0.04 | top1 | 1 | 0.04 | 0.00024 | -5.1 | 5.1 | 3.4e-07 | 0.95 | 0.14 | 0.66 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.