Hub : Traits : Extensor digitorum longus weight : ← : →

chr8:69,336,832-75,537,324

Trait: Extensor digitorum longus weight

Best TWAS P=2.74e-09 · Best GWAS P=1.65e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ccpg1	alternative polyA	ENSRNOT00000085403	0.13	1	0.08	8.2e-09	-5.41	6.48e-08	0.4	TRUE
Adipose	Ccpg1	alternative polyA	ENSRNOT00000106816	0.09	1	0.04	9.9e-06	-5.15	2.67e-07	0.09	FALSE
Adipose	Myzap	alternative polyA	ENSRNOT00000077999	0.07	1396	0.05	1.5e-06	-5.9	3.62e-09	0.47	FALSE
Adipose	Myzap	alternative polyA	ENSRNOT00000086185	0.06	1396	0.05	4.7e-06	5.89	3.94e-09	0.47	FALSE
Adipose	Myzap	alternative TSS	ENSRNOT00000085843	0.03	65	0.02	3.4e-03	5.23	1.70e-07	0.2	FALSE
Adipose	Myzap	alternative TSS	ENSRNOT00000086185	0.04	44	0.02	2.1e-03	-5.15	2.60e-07	0.22	TRUE
Adipose	Ice2	gene expression	ENSRNOG00000010160	0.09	1	0.06	3.4e-07	-5.58	2.38e-08	0.65	FALSE
Adipose	Rsl24d1	gene expression	ENSRNOG00000052787	0.29	120	0.28	1.3e-30	-5.24	1.58e-07	0.25	FALSE
Adipose	Bnip2	gene expression	ENSRNOG00000056024	0.03	1	0.02	6.2e-03	5.51	3.65e-08	0.03	FALSE
Adipose	Tcf12	gene expression	ENSRNOG00000057754	0.04	1	0.02	6.3e-03	-5.73	1.01e-08	0.04	FALSE
Adipose	Pigb	gene expression	ENSRNOG00000059622	0.07	22	0.08	2.2e-09	-5.4	6.55e-08	0.67	FALSE
Adipose	Rnf111	gene expression	ENSRNOG00000060750	0.03	782	0.02	1.4e-03	-5.67	1.40e-08	0.47	FALSE
Adipose	Mindy2	gene expression	ENSRNOG00000061337	0.08	1086	0.07	4.1e-08	5.66	1.50e-08	0.47	FALSE
Adipose	Aqp9	gene expression	ENSRNOG00000061883	0.02	1389	0.01	8.5e-03	-5.67	1.42e-08	0.3	FALSE
Adipose	Myo1e	gene expression	ENSRNOG00000061928	0.44	21	0.34	1.1e-38	5.46	4.68e-08	0.46	FALSE
Adipose	ENSRNOG00000065465	gene expression	ENSRNOG00000065465	0.03	1	0.04	1.9e-05	5.38	7.56e-08	0.07	FALSE
Adipose	Pygo1	gene expression	ENSRNOG00000066086	0.02	1308	0.01	2.5e-02	-5.58	2.45e-08	0.37	FALSE
Adipose	Ccpg1	isoform ratio	ENSRNOT00000090970	0.09	1	0.09	3.3e-10	5.41	6.48e-08	0.4	FALSE
Adipose	Myzap	isoform ratio	ENSRNOT00000077999	0.02	1396	0.01	2.5e-02	-5.92	3.23e-09	0.24	FALSE
Adipose	Myzap	isoform ratio	ENSRNOT00000085843	0.02	1396	0.02	3.2e-03	5.93	3.03e-09	0.38	FALSE
Adipose	Adam10	mRNA stability	ENSRNOG00000054257	0.07	1077	0.06	5.6e-07	-5.62	1.95e-08	0.45	FALSE
Adipose	Bnip2	mRNA stability	ENSRNOG00000056024	0.41	1	0.19	3.7e-20	5.46	4.78e-08	0.25	FALSE
Adipose	Myo1e	mRNA stability	ENSRNOG00000061928	0.07	1	0.06	1.5e-07	5.72	1.04e-08	0.6	FALSE
BLA	Ccpg1	alternative polyA	ENSRNOT00000090970	0.09	1	0.08	5.2e-05	5.41	6.39e-08	0.14	FALSE
BLA	Ccpg1	alternative polyA	ENSRNOT00000090970	0.11	1	0.09	9.8e-06	5.41	6.39e-08	0.22	FALSE
BLA	Rab27a	gene expression	ENSRNOG00000052499	0.44	12	0.38	2.6e-21	5.57	2.56e-08	0.8	FALSE
BLA	Tex9	gene expression	ENSRNOG00000059702	0.19	1245	0.12	5.7e-07	5.56	2.77e-08	0.79	FALSE
BLA	Aqp9	gene expression	ENSRNOG00000061883	0.42	1389	0.38	2.1e-21	5.64	1.74e-08	0.38	FALSE
BLA	Myo1e	gene expression	ENSRNOG00000061928	0.08	1015	0.08	5.7e-05	5.68	1.38e-08	0.49	FALSE
BLA	Ccpg1	isoform ratio	ENSRNOT00000090970	0.13	1	0.12	4.0e-07	5.41	6.39e-08	0.35	FALSE
BLA	Adam10	mRNA stability	ENSRNOG00000054257	0.1	1	0.1	8.0e-06	5.82	5.88e-09	0.44	FALSE
BLA	Prtg	mRNA stability	ENSRNOG00000055251	0.06	1	0.05	7.7e-04	5.41	6.24e-08	0.04	FALSE
BLA	Aqp9	mRNA stability	ENSRNOG00000061883	0.31	1389	0.31	2.7e-17	5.66	1.51e-08	0.41	FALSE
Brain	Ccpg1	alternative polyA	ENSRNOT00000090970	0.04	1	0.04	2.9e-04	5.16	2.42e-07	0.05	FALSE
Brain	Ccpg1	alternative polyA	ENSRNOT00000090970	0.05	1	0.05	2.3e-05	5.16	2.42e-07	0.08	FALSE
Brain	Ccpg1	alternative polyA	ENSRNOT00000106816	0.07	1	0.07	6.4e-07	-5.13	2.85e-07	0.13	FALSE
Brain	Rab27a	gene expression	ENSRNOG00000052499	0.13	1	0.15	4.5e-14	5.85	4.78e-09	0.87	FALSE
Brain	Rsl24d1	gene expression	ENSRNOG00000052787	0.24	1	0.27	1.4e-24	-5.83	5.42e-09	0.82	FALSE
Brain	Adam10	gene expression	ENSRNOG00000054257	0.21	1077	0.23	1.1e-20	-5.67	1.44e-08	0.46	FALSE
Brain	Khdc3	gene expression	ENSRNOG00000054460	0.04	1	0.05	2.1e-05	5.13	2.85e-07	0.05	FALSE
Brain	Aldh1a2	gene expression	ENSRNOG00000055049	0.41	1412	0.45	2.7e-46	-5.77	8.11e-09	0.44	FALSE
Brain	Mir628	gene expression	ENSRNOG00000056387	0.04	1	0.04	1.5e-04	-5.1	3.48e-07	0.03	FALSE
Brain	Fam81a	gene expression	ENSRNOG00000057501	0.16	18	0.15	5.2e-14	-5.71	1.12e-08	0.51	FALSE
Brain	Myzap	gene expression	ENSRNOG00000057676	0.03	1	0.03	1.2e-03	-5.42	5.83e-08	0.04	TRUE
Brain	Pigb	gene expression	ENSRNOG00000059622	0.09	12	0.11	5.0e-10	-5.61	1.97e-08	0.6	FALSE
Brain	Tex9	gene expression	ENSRNOG00000059702	0.5	1	0.27	1.6e-25	5.41	6.22e-08	0.33	FALSE
Brain	Rnf111	gene expression	ENSRNOG00000060750	0.04	782	0.04	2.0e-04	-5.7	1.16e-08	0.57	FALSE
Brain	Aqp9	gene expression	ENSRNOG00000061883	0.48	1389	0.54	3.8e-59	5.68	1.32e-08	0.44	FALSE
Brain	Myo1e	gene expression	ENSRNOG00000061928	0.03	1015	0.02	2.2e-03	5.67	1.42e-08	0.44	FALSE
Brain	Bnip2	isoform ratio	ENSRNOT00000102436	0.04	1	0.03	4.5e-04	5.62	1.91e-08	0.04	FALSE
Brain	Dnaaf4	intron excision ratio	chr8:73700709:73703207	0.03	4	0.01	2.8e-02	-5.4	6.82e-08	0.28	FALSE
Brain	Aqp9	intron excision ratio	chr8:71832397:71833310	0.02	1389	0.02	3.6e-03	5.67	1.45e-08	0.34	FALSE
Brain	Pygo1	intron excision ratio	chr8:73700709:73703207	0.03	1348	0.01	3.0e-02	-5.22	1.78e-07	0.29	FALSE
Brain	Adam10	mRNA stability	ENSRNOG00000054257	0.23	1077	0.15	3.3e-14	5.42	5.99e-08	0.42	FALSE
Brain	Bnip2	mRNA stability	ENSRNOG00000056024	0.07	1399	0.08	1.6e-07	5.61	2.01e-08	0.38	FALSE
Brain	Fam81a	mRNA stability	ENSRNOG00000057501	0.04	1	0.03	4.9e-04	-5.6	2.17e-08	0.05	FALSE
Brain	Pigb	mRNA stability	ENSRNOG00000059622	0.05	1	0.05	3.4e-05	5.11	3.27e-07	0.05	FALSE
Brain	Aqp9	mRNA stability	ENSRNOG00000061883	0.3	50	0.32	1.5e-30	5.61	2.06e-08	0.43	FALSE
Eye	Rnf111	gene expression	ENSRNOG00000060750	0.3	1	0.08	2.6e-02	-5.88	4.17e-09	0.06	FALSE
Eye	Myo1e	intron excision ratio	chr8:71002950:71005244	0.39	1	0.24	1.2e-04	-5.51	3.65e-08	0.06	FALSE
Eye	Myo1e	intron excision ratio	chr8:71005378:71007731	0.37	1	0.19	7.0e-04	5.51	3.65e-08	0.06	FALSE
IL	Bnip2	alternative polyA	ENSRNOT00000081072	0.19	1389	0.1	1.8e-03	5.63	1.81e-08	0.33	FALSE
IL	Bnip2	alternative polyA	ENSRNOT00000087382	0.18	1389	0.1	1.8e-03	-5.63	1.84e-08	0.32	FALSE
IL	Bnip2	alternative polyA	ENSRNOT00000081072	0.23	1389	0.12	9.7e-04	5.64	1.67e-08	0.36	FALSE
IL	Bnip2	alternative polyA	ENSRNOT00000087382	0.23	1389	0.12	9.7e-04	-5.65	1.65e-08	0.36	FALSE
IL	Rab27a	gene expression	ENSRNOG00000052499	0.3	1	0.21	1.1e-05	5.65	1.60e-08	0.16	FALSE
IL	Adam10	gene expression	ENSRNOG00000054257	0.37	1073	0.22	6.8e-06	-5.63	1.76e-08	0.46	FALSE
IL	Aqp9	gene expression	ENSRNOG00000061883	0.33	1	0.21	1.2e-05	5.57	2.60e-08	0.07	FALSE
IL	Adam10	mRNA stability	ENSRNOG00000054257	0.26	1	0.13	6.1e-04	5.43	5.75e-08	0.06	FALSE
IL	Bnip2	mRNA stability	ENSRNOG00000056024	0.23	1389	0.13	4.1e-04	5.64	1.69e-08	0.39	FALSE
IL	Rfx7	mRNA stability	ENSRNOG00000060367	0.17	1226	0.07	1.0e-02	-5.16	2.53e-07	0.46	FALSE
IL	Aqp9	mRNA stability	ENSRNOG00000061883	0.27	1387	0.15	1.8e-04	5.66	1.50e-08	0.39	FALSE
LHb	Aqp9	gene expression	ENSRNOG00000061883	0.45	1	0.22	7.6e-06	5.57	2.61e-08	0.07	FALSE
Liver	Ccpg1	alternative polyA	ENSRNOT00000085403	0.05	22	0.04	9.9e-06	-5.12	3.01e-07	0.44	FALSE
Liver	Bnip2	alternative polyA	ENSRNOT00000081072	0.25	1	0.13	4.6e-14	5.51	3.65e-08	0.3	FALSE
Liver	Bnip2	alternative polyA	ENSRNOT00000087382	0.18	1399	0.11	1.4e-12	-5.59	2.28e-08	0.39	FALSE
Liver	Bnip2	alternative polyA	ENSRNOT00000081072	0.25	1	0.13	4.1e-14	5.57	2.51e-08	0.38	FALSE
Liver	Bnip2	alternative polyA	ENSRNOT00000087382	0.18	1399	0.11	2.1e-12	-5.59	2.22e-08	0.4	FALSE
Liver	Rsl24d1	gene expression	ENSRNOG00000052787	0.11	1	0.11	1.7e-12	-5.38	7.56e-08	0.27	FALSE
Liver	Adam10	gene expression	ENSRNOG00000054257	0.02	1	0.01	2.5e-02	5.72	1.04e-08	0.03	FALSE
Liver	Bnip2	gene expression	ENSRNOG00000056024	0.16	1399	0.13	3.2e-14	5.62	1.86e-08	0.4	FALSE
Liver	Pigb	gene expression	ENSRNOG00000059622	0.03	60	0.02	1.2e-03	-5.11	3.22e-07	0.47	FALSE
Liver	Tex9	gene expression	ENSRNOG00000059702	0.39	20	0.28	4.6e-31	5.23	1.67e-07	0.27	FALSE
Liver	Mindy2	gene expression	ENSRNOG00000061337	0.05	1086	0.03	5.1e-04	5.59	2.21e-08	0.43	FALSE
Liver	Aqp9	gene expression	ENSRNOG00000061883	0.02	165	0.01	6.7e-03	5.81	6.08e-09	0.25	FALSE
Liver	ENSRNOG00000065465	gene expression	ENSRNOG00000065465	0.12	14	0.07	1.2e-08	5.19	2.15e-07	0.55	FALSE
Liver	ENSRNOG00000065802	gene expression	ENSRNOG00000065802	0.03	1466	0.02	3.5e-03	-5.41	6.28e-08	0.36	FALSE
Liver	Bnip2	isoform ratio	ENSRNOT00000081072	0.07	1	0.03	1.4e-04	5.51	3.65e-08	0.05	FALSE
Liver	Bnip2	isoform ratio	ENSRNOT00000087382	0.3	1	0.07	7.9e-08	-5.57	2.51e-08	0.37	FALSE
Liver	Bnip2	mRNA stability	ENSRNOG00000056024	0.04	5	0.02	1.7e-03	5.66	1.54e-08	0.4	FALSE
Liver	Aqp9	mRNA stability	ENSRNOG00000061883	0.04	1389	0.03	4.6e-04	-5.67	1.44e-08	0.41	FALSE
NAcc	Rab27a	gene expression	ENSRNOG00000052499	0.12	1598	0.12	4.1e-09	5.27	1.36e-07	0.83	FALSE
NAcc	Rsl24d1	gene expression	ENSRNOG00000052787	0.09	1	0.07	7.4e-06	-5.75	8.88e-09	0.62	TRUE
NAcc	Adam10	gene expression	ENSRNOG00000054257	0.04	1	0.03	4.4e-03	-5.82	5.88e-09	0.08	FALSE
NAcc	Wdr72	gene expression	ENSRNOG00000054889	0.06	1	0.04	3.4e-04	5.2	2.01e-07	0.03	FALSE
NAcc	Aldh1a2	gene expression	ENSRNOG00000055049	0.07	1412	0.09	4.3e-07	-5.67	1.44e-08	0.45	FALSE
NAcc	Unc13c	gene expression	ENSRNOG00000056612	0.09	1	0.14	1.5e-10	-5.83	5.55e-09	0.63	FALSE
NAcc	Nedd4	gene expression	ENSRNOG00000058898	0.08	22	0.09	1.7e-07	5.45	5.15e-08	0.01	TRUE
NAcc	Gcnt3	gene expression	ENSRNOG00000059540	0.04	1	0.04	2.6e-04	5.66	1.56e-08	0.05	FALSE
NAcc	Pigb	gene expression	ENSRNOG00000059622	0.11	16	0.08	1.7e-06	-5.95	2.74e-09	0.64	TRUE
NAcc	Tex9	gene expression	ENSRNOG00000059702	0.25	1	0.14	2.3e-10	5.27	1.39e-07	0.19	FALSE
NAcc	Aqp9	gene expression	ENSRNOG00000061883	0.26	1	0.31	1.6e-23	5.63	1.79e-08	0.36	FALSE
NAcc	ENSRNOG00000069347	gene expression	ENSRNOG00000069347	0.1	1	0.06	3.7e-05	5.75	9.03e-09	0.44	FALSE
NAcc	Bnip2	mRNA stability	ENSRNOG00000056024	0.05	1399	0.06	5.8e-05	5.61	2.00e-08	0.4	FALSE
NAcc	Unc13c	mRNA stability	ENSRNOG00000056612	0.04	1	0.03	5.4e-03	-5.83	5.55e-09	0.05	FALSE
NAcc	Fam81a	mRNA stability	ENSRNOG00000057501	0.04	1044	0.03	1.4e-03	-5.68	1.38e-08	0.46	FALSE
NAcc	Pigb	mRNA stability	ENSRNOG00000059622	0.05	1550	0.03	5.4e-03	5.51	3.69e-08	0.53	FALSE
NAcc	Aqp9	mRNA stability	ENSRNOG00000061883	0.24	1	0.22	1.7e-16	5.37	7.69e-08	0.12	FALSE
OFC	Rab27a	gene expression	ENSRNOG00000052499	0.36	1	0.05	2.1e-02	5.82	5.75e-09	0.07	FALSE
OFC	Aldh1a2	gene expression	ENSRNOG00000055049	0.16	1410	0.07	8.6e-03	-5.65	1.61e-08	0.27	FALSE
OFC	Unc13c	gene expression	ENSRNOG00000056612	0.18	1	0.1	2.7e-03	-5.85	4.99e-09	0.06	TRUE
OFC	Dnaaf4	gene expression	ENSRNOG00000056654	0.18	1	0.12	9.5e-04	-5.21	1.93e-07	0.05	FALSE
OFC	Aqp9	gene expression	ENSRNOG00000061883	0.43	1	0.17	7.2e-05	5.63	1.77e-08	0.07	FALSE
OFC	Fam81a	mRNA stability	ENSRNOG00000057501	0.22	1037	0.12	8.9e-04	-5.68	1.39e-08	0.44	FALSE
OFC	Aqp9	mRNA stability	ENSRNOG00000061883	0.29	3	0.15	1.6e-04	5.68	1.39e-08	0.4	FALSE
PL	Ccpg1	alternative polyA	ENSRNOT00000090970	0.12	9	0.1	5.9e-08	5.91	3.35e-09	0.81	FALSE
PL	Ccpg1	alternative polyA	ENSRNOT00000090970	0.11	1	0.12	4.3e-09	5.83	5.57e-09	0.88	FALSE
PL	Bnip2	alternative polyA	ENSRNOT00000081072	0.03	1399	0.01	2.4e-02	5.63	1.83e-08	0.34	FALSE
PL	Bnip2	alternative polyA	ENSRNOT00000087382	0.03	1399	0.01	2.7e-02	-5.63	1.81e-08	0.34	FALSE
PL	Rab27a	gene expression	ENSRNOG00000052499	0.3	36	0.34	2.1e-26	5.57	2.52e-08	0.8	FALSE
PL	Adam10	gene expression	ENSRNOG00000054257	0.07	1	0.07	3.4e-06	-5.74	9.36e-09	0.43	FALSE
PL	Khdc3	gene expression	ENSRNOG00000054460	0.11	52	0.08	8.1e-07	5.33	9.93e-08	0.6	FALSE
PL	AC142458.1	gene expression	ENSRNOG00000054641	0.13	51	0.14	1.3e-10	5.66	1.47e-08	0.59	FALSE
PL	Wdr72	gene expression	ENSRNOG00000054889	0.16	1	0.2	6.0e-15	5.91	3.32e-09	0.76	FALSE
PL	Aldh1a2	gene expression	ENSRNOG00000055049	0.15	1412	0.15	7.6e-12	-5.78	7.56e-09	0.46	FALSE
PL	Unc13c	gene expression	ENSRNOG00000056612	0.05	2525	0.03	4.0e-03	-5.24	1.58e-07	0.34	FALSE
PL	Dnaaf4	gene expression	ENSRNOG00000056654	0.04	1	0.02	8.7e-03	-5.78	7.62e-09	0.08	FALSE
PL	Fam81a	gene expression	ENSRNOG00000057501	0.1	1044	0.12	1.9e-09	-5.65	1.59e-08	0.47	FALSE
PL	Pigb	gene expression	ENSRNOG00000059622	0.04	1	0.02	7.2e-03	-5.81	6.16e-09	0.06	FALSE
PL	Aqp9	gene expression	ENSRNOG00000061883	0.51	1389	0.4	7.3e-32	5.66	1.50e-08	0.43	FALSE
PL	Ccpg1	isoform ratio	ENSRNOT00000090970	0.13	9	0.11	6.2e-09	5.89	3.79e-09	0.8	FALSE
PL	Fam81a	intron excision ratio	chr8:70803970:70820689	0.03	1044	0.02	9.3e-03	5.65	1.58e-08	0.43	FALSE
PL	Fam81a	intron excision ratio	chr8:70803970:70821437	0.03	1044	0.02	8.4e-03	-5.66	1.54e-08	0.43	FALSE
PL	Rab27a	mRNA stability	ENSRNOG00000052499	0.07	1	0.06	4.4e-05	-5.79	7.09e-09	0.29	FALSE
PL	Adam10	mRNA stability	ENSRNOG00000054257	0.26	14	0.25	4.4e-19	5.47	4.42e-08	0.39	FALSE
PL	Bnip2	mRNA stability	ENSRNOG00000056024	0.09	1399	0.08	7.5e-07	5.63	1.80e-08	0.41	FALSE
PL	Pigb	mRNA stability	ENSRNOG00000059622	0.05	1	0.04	3.5e-04	5.79	6.88e-09	0.12	FALSE
PL	Aqp9	mRNA stability	ENSRNOG00000061883	0.26	1389	0.25	4.4e-19	5.68	1.31e-08	0.45	FALSE