Hub : Traits : Bone: cortical area :

chr10:105,499,327-107,195,627

Trait: Bone: cortical area

Best TWAS P=9.116832e-14 · Best GWAS P=1.535422e-09 conditioned to 0.0151798

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Tbcd	mRNA stability	ENSRNOG00000036658	0.10	0.04	blup	1813	0.06	6.6e-07	-3.4	-5.3	1.2e-07	-0.79	0.39	0.61	FALSE
2	BLA	B3gntl1	mRNA stability	ENSRNOG00000049724	0.12	0.04	enet	13	0.07	1.3e-04	-3.2	-5.3	1.2e-07	-0.80	0.34	0.62	FALSE
3	LHb	NA	mRNA stability	ENSRNOG00000068691	0.35	0.05	enet	47	0.13	4.8e-04	4.0	5.2	1.6e-07	0.57	0.25	0.20	FALSE
4	NAcc	Ccdc57	alternative TSS	ENSRNOT00000095877	0.27	0.02	blup	1793	0.02	5.9e-03	-3.4	7.5	9.1e-14	0.54	0.30	0.06	TRUE
5	NAcc	Ccdc57	alternative TSS	ENSRNOT00000098223	0.24	0.02	blup	1793	0.02	7.7e-03	-3.4	-7.4	1.6e-13	-0.54	0.30	0.06	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.