Hub : Traits : Bone: minimum diameter : ← : →

chr10:89,689,463-93,678,531

Trait: Bone: minimum diameter

Best TWAS P = 9.52e-09 · Best GWAS P= 1.21e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Icam2	alternative TSS	XM_063269465.1	0.12	7	0.13	6.7e-14	-5.25	1.51e-07	0.76	FALSE
Adipose	C10h17orf58	gene expression	C10h17orf58	0.32	60	0.41	9.2e-49	-5.34	9.12e-08	0.7	FALSE
Adipose	Taco1	gene expression	Taco1	0.05	1	0.04	9.8e-06	5.43	5.63e-08	0.64	FALSE
Adipose	Tanc2	gene expression	Tanc2	0.23	1	0.22	1.1e-23	-5.29	1.25e-07	0.75	FALSE
Adipose	Scn4a	mRNA stability	Scn4a	0.04	2215	0.03	3.4e-04	-5.6	2.11e-08	0.65	FALSE
BLA	Helz	alternative polyA	XM_063268757.1	0.07	2077	0.04	3.5e-03	-5.25	1.55e-07	0.36	FALSE
BLA	Helz	alternative polyA	XM_063268757.1	0.07	2077	0.04	4.3e-03	-5.25	1.53e-07	0.41	TRUE
BLA	Ace	gene expression	Ace	0.17	14	0.18	4.9e-10	5.72	1.04e-08	0.32	TRUE
BLA	Ccdc47	gene expression	Ccdc47	0.07	1	0.03	1.4e-02	-5.41	6.32e-08	0.07	FALSE
BLA	Bptf	mRNA stability	Bptf	0.04	1896	0.03	1.1e-02	5.24	1.59e-07	0.52	FALSE
BLA	Strada	mRNA stability	Strada	0.09	49	0.1	8.5e-06	-5.34	9.11e-08	0.51	FALSE
Brain	Ace	gene expression	Ace	0.1	1	0.1	7.2e-10	5.33	9.69e-08	0.7	FALSE
Brain	Kcnh6	gene expression	Kcnh6	0.05	1	0.03	1.3e-03	5.33	9.69e-08	0.15	FALSE
Brain	LOC134480889	gene expression	LOC134480889	0.07	2519	0.07	8.6e-07	-5.51	3.67e-08	0.37	FALSE
Brain	Scn4a	gene expression	Scn4a	0.46	14	0.45	5.5e-46	5.35	8.85e-08	0.74	FALSE
Brain	Tex2	isoform ratio	NM_001100554.1	0.05	10	0.05	2.7e-05	5.24	1.58e-07	0.3	TRUE
Brain	Tex2	isoform ratio	XM_006247647.4	0.05	17	0.05	2.1e-05	-5.39	7.00e-08	0.41	FALSE
Brain	Bptf	mRNA stability	Bptf	0.12	1896	0.12	4.8e-11	5.52	3.45e-08	0.73	TRUE
Brain	Taco1	mRNA stability	Taco1	0.14	13	0.18	6.1e-17	-5.51	3.52e-08	0.65	TRUE
IC	Prr29	alternative polyA	XM_213490.11	0.07	2217	0.06	1.4e-03	5.21	1.89e-07	0.37	FALSE
IC	Prr29	alternative TSS	XM_213490.11	0.09	2217	0.04	8.6e-03	5.32	1.05e-07	0.38	FALSE
IC	Ace	gene expression	Ace	0.41	2171	0.35	1.2e-15	-5.3	1.14e-07	0.68	FALSE
IC	C10h17orf58	gene expression	C10h17orf58	0.51	53	0.43	1.3e-19	-5.4	6.84e-08	0.69	FALSE
IC	Dcaf7	gene expression	Dcaf7	0.14	67	0.14	2.2e-06	5.69	1.25e-08	0.52	FALSE
IC	Icam2	gene expression	Icam2	0.08	2216	0.05	4.9e-03	5.39	7.22e-08	0.5	FALSE
IC	LOC134480889	gene expression	LOC134480889	0.28	213	0.26	2.4e-11	5.62	1.96e-08	0.14	FALSE
IC	Strada	mRNA stability	Strada	0.06	1	0.06	1.2e-03	-5.32	1.05e-07	0.06	FALSE
IL	Cyb561	alternative TSS	NM_001107056.3	0.3	22	0.02	9.9e-02	-5.63	1.85e-08	0.36	TRUE
IL	C10h17orf58	gene expression	C10h17orf58	0.35	2054	0.3	6.8e-08	-5.21	1.86e-07	0.6	FALSE
IL	LOC134480889	gene expression	LOC134480889	0.18	2519	0.09	3.9e-03	-5.59	2.26e-08	0.3	FALSE
IL	Cyb561	isoform ratio	NM_001107056.3	0.64	2180	0.24	1.7e-06	5.56	2.68e-08	0.5	TRUE
IL	Pecam1	mRNA stability	Pecam1	0.22	11	0.13	5.7e-04	-5.34	9.14e-08	0.41	FALSE
IL	Strada	mRNA stability	Strada	0.34	1	0.32	1.4e-08	-5.39	6.89e-08	0.51	FALSE
LHb	Cyb561	alternative TSS	NM_001107056.3	0.68	15	0.26	6.5e-07	5.31	1.09e-07	0.11	FALSE
LHb	Cyb561	alternative TSS	XM_039086163.2	0.3	4	0.1	2.0e-03	-5.4	6.73e-08	0.16	FALSE
LHb	Scn4a	gene expression	Scn4a	0.66	1	0.31	4.9e-08	-5.39	6.94e-08	0.72	FALSE
LHb	Taco1	mRNA stability	Taco1	0.18	1	0.09	3.8e-03	5.25	1.55e-07	0.07	FALSE
Liver	Icam2	alternative polyA	XM_006247624.5	0.02	1	0.02	1.2e-03	-5.29	1.25e-07	0.08	FALSE
Liver	Icam2	alternative polyA	XM_039086420.2	0.02	2216	0.01	9.5e-03	-5.47	4.52e-08	0.56	FALSE
Liver	Icam2	alternative TSS	XM_063269465.1	0.02	2216	0.01	7.1e-03	-5.45	5.13e-08	0.62	FALSE
Liver	Icam2	alternative TSS	XM_063269469.1	0.07	1	0.07	5.8e-08	-5.24	1.60e-07	0.64	FALSE
Liver	Polg2	alternative TSS	NM_001107060.1	0.04	2270	0.04	7.2e-05	5.21	1.90e-07	0.62	TRUE
Liver	Ace	gene expression	Ace	0.08	2171	0.08	4.6e-09	-5.5	3.80e-08	0.62	FALSE
Liver	Dcaf7	gene expression	Dcaf7	0.04	38	0.05	2.3e-06	5.22	1.79e-07	0.57	FALSE
Liver	Icam2	isoform ratio	XM_006247624.5	0.09	1	0.07	3.8e-08	-5.29	1.22e-07	0.7	FALSE
Liver	Icam2	intron excision ratio	chr10_91813510_91815000	0.31	1	0.27	1.1e-29	5.33	9.94e-08	0.74	FALSE
Liver	Icam2	mRNA stability	Icam2	0.07	8	0.07	3.1e-08	5.49	4.07e-08	0.69	FALSE
Liver	Kpna2	mRNA stability	Kpna2	0.04	75	0.02	4.1e-03	-5.54	2.97e-08	0.59	TRUE
Liver	Map3k3	mRNA stability	Map3k3	0.02	1	0.02	2.7e-03	5.36	8.48e-08	0.06	FALSE
Liver	Taco1	mRNA stability	Taco1	0.09	13	0.11	5.1e-12	-5.51	3.55e-08	0.67	FALSE
NAcc	Pecam1	alternative TSS	NM_031591.2	0.05	2283	0.05	3.0e-08	-5.27	1.39e-07	0.62	FALSE
NAcc	C10h17orf58	gene expression	C10h17orf58	0.56	65	0.63	3.1e-123	-5.26	1.45e-07	0.74	FALSE
NAcc	Ccdc47	gene expression	Ccdc47	0.05	29	0.05	2.8e-08	-5.73	1.01e-08	0.72	FALSE
NAcc	Dcaf7	gene expression	Dcaf7	0.02	2014	0.01	2.7e-03	-5.3	1.13e-07	0.22	TRUE
NAcc	Ddx42	gene expression	Ddx42	0.02	1	0.02	3.2e-04	5.38	7.55e-08	0.26	FALSE
NAcc	Scn4a	gene expression	Scn4a	0.42	8	0.48	2.0e-83	5.3	1.13e-07	0.74	TRUE
NAcc	Tanc2	gene expression	Tanc2	0.18	18	0.11	8.4e-17	-5.37	7.71e-08	0.74	TRUE
NAcc	Tex2	gene expression	Tex2	0.44	29	0.39	1.1e-63	-5.49	3.92e-08	0.08	FALSE
NAcc	LOC108352141	intron excision ratio	chr10_90344450_90356529	0.08	3523	0.06	3.5e-10	5.36	8.21e-08	0.56	FALSE
NAcc	Taco1	mRNA stability	Taco1	0.13	6	0.15	4.9e-22	-5.34	9.44e-08	0.7	FALSE
OFC	Tlk2	alternative TSS	XM_039086141.2	0.18	3342	0.03	7.1e-02	-5.33	9.75e-08	0.44	FALSE
OFC	Tlk2	alternative TSS	XM_039086141.2	0.17	3342	0.03	7.5e-02	-5.41	6.33e-08	0.45	FALSE
OFC	Ace	gene expression	Ace	0.46	2171	0.27	5.0e-07	-5.53	3.13e-08	0.64	FALSE
OFC	LOC134480889	gene expression	LOC134480889	0.32	13	0.15	2.3e-04	-5.35	8.79e-08	0.26	TRUE
PL	Icam2	alternative TSS	XM_063269465.1	0.04	2216	0.02	1.8e-03	-5.23	1.68e-07	0.66	TRUE
PL	Icam2	alternative TSS	XM_063269465.1	0.03	2216	0.03	4.7e-04	-5.42	5.88e-08	0.62	FALSE
PL	Pecam1	alternative TSS	NM_031591.2	0.06	2283	0.06	2.8e-07	-5.44	5.19e-08	0.52	FALSE
PL	Pecam1	alternative TSS	XM_039085778.2	0.06	1	0.08	2.6e-09	-5.29	1.20e-07	0.79	FALSE
PL	Ace	gene expression	Ace	0.16	22	0.29	7.7e-32	-5.26	1.41e-07	0.69	TRUE
PL	C10h17orf58	gene expression	C10h17orf58	0.43	67	0.5	5.9e-62	5.3	1.18e-07	0.74	FALSE
PL	LOC134480889	gene expression	LOC134480889	0.08	10	0.08	6.6e-09	5.63	1.75e-08	0.15	FALSE
PL	Mrc2	gene expression	Mrc2	0.12	91	0.13	1.1e-13	-5.35	8.59e-08	0.62	TRUE
PL	Polg2	gene expression	Polg2	0.04	32	0.04	2.8e-05	5.23	1.67e-07	0.5	FALSE
PL	Tlk2	isoform ratio	XM_006247574.5	0.06	1	0.05	2.7e-06	-5.31	1.10e-07	0.85	TRUE
PL	Cyb561	intron excision ratio	chr10_91384349_91388418	0.09	10	0.09	2.0e-10	-5.74	9.52e-09	0.08	TRUE
pVTA	C10h17orf58	gene expression	C10h17orf58	0.4	93	0.45	2.9e-39	-5.34	9.52e-08	0.71	TRUE
pVTA	Ccdc47	gene expression	Ccdc47	0.04	2131	0.04	6.5e-04	5.43	5.54e-08	0.52	FALSE
pVTA	Cyb561	gene expression	Cyb561	0.08	4	0.09	9.3e-08	-5.45	4.93e-08	0.62	FALSE
pVTA	Dcaf7	gene expression	Dcaf7	0.03	2014	0.01	4.6e-02	-5.42	5.87e-08	0.32	FALSE
pVTA	LOC134480889	gene expression	LOC134480889	0.05	2519	0.02	7.4e-03	-5.32	1.05e-07	0.26	FALSE
pVTA	Cyb561	intron excision ratio	chr10_91384349_91388418	0.25	27	0.21	9.0e-17	-5.42	5.92e-08	0.07	FALSE
pVTA	Ftsj3	mRNA stability	Ftsj3	0.04	1	0.04	2.2e-04	-5.36	8.31e-08	0.39	FALSE
pVTA	Taco1	mRNA stability	Taco1	0.09	3	0.13	2.9e-10	-5.22	1.82e-07	0.57	FALSE
RMTg	Scn4a	gene expression	Scn4a	0.3	17	0.33	1.5e-09	5.31	1.09e-07	0.61	TRUE