Hub : Traits

tautz: manual_mpc1

Project: tautz

1 significantly associated model · 1 unique gene

Significant Loci

# chr p0 p1 # assoc genes # joint models best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 201865024 202832586 1 1 8e-12 0.0042 0.029 42 Ccs

p0: physical position of the start of the locus. p1: physical position of the end of the locus. # joint models: number of models selected by step-wise conditional analysis.

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Number of licking bursts 8.1 1 0 0 0 1 Ccs
Food consumed during 24 hour testing period 18.6 1 0 0 0 1 Ccs
Water consumed over 24 hour session 11.5 1 0 0 0 1 Ccs
Average drop size 5.0 1 0 0 0 1 Ccs
reaction_time_peropinit_slope 3.9 1 0 0 0 1 Ccs
tautz: manual_spc9 12.9 1 0 0 0 1 Ccs
tautz: manual_mpc3 3.2 1 0 0 0 1 Ccs
tautz: manual_spc8 48.6 1 1 100 0 1 Ccs
tautz: manual_mpc4 43.2 1 1 100 0 1 Ccs
tautz: manual_spc22 6.9 1 0 0 0 1 Ccs
tautz: manual_mcs 4.9 1 0 0 0 1 Ccs
tautz: manual_spc17 3.0 1 0 0 0 1 Ccs
tautz: manual_mpc19 3.6 1 0 0 0 1 Ccs
tautz: manual_spc10 28.4 1 1 100 0 1 Ccs
tautz: manual_spc11 3.6 1 0 0 0 1 Ccs
tautz: manual_spc23 3.3 1 0 0 0 1 Ccs
tautz: manual_spc6 4.2 1 0 0 0 1 Ccs
tautz: manual_mpc2 16.6 1 0 0 0 1 Ccs
tautz: manual_spc1 24.0 1 1 100 0 1 Ccs
tautz: manual_spc16 19.8 1 0 0 0 1 Ccs
tautz: manual_spc5 8.9 1 0 0 0 1 Ccs
tautz: manual_mpc6 6.1 1 0 0 0 1 Ccs
tautz: manual_spc18 9.4 1 0 0 0 1 Ccs
tautz: manual_mpc11 24.9 1 1 100 0 1 Ccs
tautz: manual_spc19 6.0 1 0 0 0 1 Ccs
Liver selenium concentration 35.1 1 1 100 0 1 Ccs
Liver iron concentration 23.9 1 1 100 0 1 Ccs
Liver cobalt concentration 35.3 1 1 100 0 1 Ccs
Liver cadmium concentration 5.8 1 0 0 0 1 Ccs
Liver zinc concentration 38.0 1 1 100 0 1 Ccs
Liver sodium concentration 11.5 1 0 0 0 1 Ccs
Liver manganese concentration 4.7 1 0 0 0 1 Ccs

chisq ratio: Average Chi2 statistic for the selected genes in the secondary trait, divided by the average statistic for all genes in the secondary trait. # genes+: Shared significant genes at Bonferroni correction. # genes++: Shared significant genes at transcriptome-wide significance. % genes++: Number of [++] genes as a percentage of primary trait’s total joint genes. corr: Correlation of effect sizes across the [+] genes.

Associations by panel

tissue modality # hits % hits/tests avg chisq
Adipose alternative polyA 0 0.000 1.2
Adipose alternative TSS 0 0.000 1.3
Adipose gene expression 0 0.000 1.3
Adipose isoform ratio 0 0.000 1.3
Adipose intron excision ratio 0 0.000 1.4
Adipose mRNA stability 0 0.000 1.2
BLA alternative polyA 0 0.000 1.2
BLA alternative TSS 0 0.000 1.3
BLA gene expression 0 0.000 1.2
BLA isoform ratio 0 0.000 1.2
BLA intron excision ratio 0 0.000 1.3
BLA mRNA stability 0 0.000 1.2
Brain alternative polyA 0 0.000 1.3
Brain alternative TSS 0 0.000 1.3
Brain gene expression 0 0.000 1.2
Brain isoform ratio 0 0.000 1.3
Brain intron excision ratio 0 0.000 1.3
Brain mRNA stability 0 0.000 1.1
Eye alternative polyA 0 0.000 1.3
Eye alternative TSS 0 0.000 1.2
Eye gene expression 0 0.000 1.3
Eye isoform ratio 0 0.000 1.3
Eye intron excision ratio 0 0.000 1.5
Eye mRNA stability 0 0.000 1.1
IL alternative polyA 0 0.000 1.4
IL alternative TSS 0 0.000 1.2
IL gene expression 0 0.000 1.2
IL isoform ratio 0 0.000 1.4
IL intron excision ratio 0 0.000 1.3
IL mRNA stability 0 0.000 1.2
LHb alternative polyA 0 0.000 1.5
LHb alternative TSS 0 0.000 1.3
LHb gene expression 0 0.000 1.3
LHb isoform ratio 0 0.000 1.4
LHb intron excision ratio 0 0.000 1.6
LHb mRNA stability 0 0.000 1.2
Liver alternative polyA 0 0.000 1.2
Liver alternative TSS 0 0.000 1.3
Liver gene expression 1 0.014 1.2
Liver isoform ratio 0 0.000 1.3
Liver intron excision ratio 0 0.000 1.3
Liver mRNA stability 0 0.000 1.2
NAcc alternative polyA 0 0.000 1.5
NAcc alternative TSS 0 0.000 1.4
NAcc gene expression 0 0.000 1.3
NAcc isoform ratio 0 0.000 1.2
NAcc intron excision ratio 0 0.000 1.5
NAcc mRNA stability 0 0.000 1.2
NAcc2 alternative polyA 0 0.000 1.3
NAcc2 alternative TSS 0 0.000 1.4
NAcc2 gene expression 0 0.000 1.2
NAcc2 isoform ratio 0 0.000 1.3
NAcc2 intron excision ratio 0 0.000 1.3
NAcc2 mRNA stability 0 0.000 1.2
OFC alternative polyA 0 0.000 1.6
OFC alternative TSS 0 0.000 1.5
OFC gene expression 0 0.000 1.2
OFC isoform ratio 0 0.000 1.3
OFC intron excision ratio 0 0.000 1.4
OFC mRNA stability 0 0.000 1.2
PL alternative polyA 0 0.000 1.4
PL alternative TSS 0 0.000 1.4
PL gene expression 0 0.000 1.2
PL isoform ratio 0 0.000 1.2
PL intron excision ratio 0 0.000 1.4
PL mRNA stability 0 0.000 1.3
PL2 alternative polyA 0 0.000 1.2
PL2 alternative TSS 0 0.000 1.3
PL2 gene expression 0 0.000 1.2
PL2 isoform ratio 0 0.000 1.2
PL2 intron excision ratio 0 0.000 1.4
PL2 mRNA stability 0 0.000 1.2

avg chisq: Average Chi2 (squared Z-score) across all models in this panel for this trait.