Best TWAS P=7.965236e-12 · Best GWAS P=0.004222937 conditioned to 0.02907557
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Ccs | gene expression | ENSRNOG00000047816 | 0.07 | 0.05 | enet | 10 | 0.06 | 5.1e-07 | -1.7 | -6.8 | 8e-12 | -0.66 | 0.07 | 0.07 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.