chr1:102,553,738-104,830,034

Trait: Left kidney weight

Best TWAS P = 1.22e-08 · Best GWAS P= 2.40e-07 conditioned to 7.94e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Prmt1 alternative TSS XM_006229144.5 0.62 29 0.09 2.4e-10 5.31 1.11e-07 0.63 FALSE
Adipose Prmt1 intron excision ratio chr1_104602489_104604508 0.08 33 0.04 3.5e-05 5.29 1.22e-07 0.6 FALSE
Adipose Rcn3 mRNA stability Rcn3 0.26 21 0.13 2.0e-14 -5.42 5.98e-08 0.63 FALSE
Adipose Scaf1 mRNA stability Scaf1 0.05 431 0.03 5.7e-04 -5.28 1.32e-07 0.56 FALSE
BLA Syt3 alternative TSS XM_039102277.1 0.12 125 0.06 6.4e-04 5.29 1.24e-07 0.55 FALSE
BLA Syt3 alternative TSS XM_063282307.1 0.12 120 0.05 9.2e-04 -5.32 1.03e-07 0.56 FALSE
Brain Cpt1c alternative TSS XM_017589139.2 0.08 23 0.05 1.4e-05 -5.44 5.33e-08 0.68 FALSE
Brain Med25 gene expression Med25 0.46 12 0.25 1.0e-22 5.25 1.49e-07 0.73 FALSE
Brain Cpt1c isoform ratio NM_001034925.2 0.06 5 0.05 2.7e-05 5.21 1.93e-07 0.43 FALSE
Brain Ctu1 intron excision ratio chr1_103252043_103254866 0.05 3350 0.02 8.0e-03 5.25 1.55e-07 0.6 FALSE
IL Josd2 mRNA stability Josd2 0.16 2173 0.04 3.7e-02 5.24 1.62e-07 0.26 FALSE
LHb Fuz alternative polyA XM_006229060.5 0.25 114 0.2 2.1e-05 5.4 6.72e-08 0.44 FALSE
LHb Med25 intron excision ratio chr1_104505814_104510610 0.18 48 0.09 4.6e-03 -5.39 6.93e-08 0.39 FALSE
NAcc C1h19orf81 intron excision ratio chr1_103994174_103994823 0.03 19 0.02 5.7e-04 5.7 1.22e-08 0.58 TRUE
NAcc Fcgrt mRNA stability Fcgrt 0.02 14 0.02 2.7e-04 -5.24 1.57e-07 0.51 FALSE
OFC Fuz alternative polyA NM_001399381.1 0.33 112 0.21 1.1e-05 -5.44 5.35e-08 0.56 FALSE
PL Med25 alternative TSS XM_063284073.1 0.03 5 0.01 3.7e-02 5.21 1.93e-07 0.43 FALSE
PL Med25 alternative TSS XM_063284073.1 0.03 5 0.01 5.9e-02 5.22 1.81e-07 0.39 FALSE
PL Tsks gene expression Tsks 0.04 15 0.04 9.4e-05 5.24 1.63e-07 0.5 FALSE
PL Fuz isoform ratio NM_001399381.1 0.03 16 0.02 6.0e-03 -5.22 1.82e-07 0.38 FALSE
pVTA Cpt1c alternative TSS NM_001034925.2 0.16 14 0.19 1.8e-15 5.46 4.73e-08 0.69 FALSE
pVTA Cpt1c alternative TSS XM_063262004.1 0.15 5 0.11 3.0e-09 -5.32 1.03e-07 0.69 FALSE
pVTA Cpt1c alternative TSS NM_001034925.2 0.2 46 0.23 2.8e-18 5.45 4.92e-08 0.69 FALSE
pVTA Cpt1c alternative TSS XM_063262004.1 0.22 5 0.13 2.4e-10 -5.46 4.84e-08 0.7 FALSE
pVTA Cpt1c mRNA stability Cpt1c 0.03 7 0.02 4.5e-03 -5.48 4.16e-08 0.46 FALSE