Hub : Traits : Left kidney weight : ← : →

chr1:257,860,954-260,518,987

Trait: Left kidney weight

Best TWAS P=2.63e-13 · Best GWAS P=1.97e-13 conditioned to NaN

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Grk5	alternative polyA	XM_039088801.1	0.1	68	0.13	8.2e-14	5.84	5.18e-09	0	FALSE
Adipose	Grk5	alternative polyA	XM_039088820.1	0.07	1	0.09	1.5e-10	-5.53	3.22e-08	0	FALSE
Adipose	Grk5	alternative polyA	XM_039088801.1	0.11	1	0.13	1.5e-14	5.37	7.90e-08	0	FALSE
Adipose	Grk5	alternative polyA	XM_039088820.1	0.07	1	0.09	3.3e-10	-5.53	3.22e-08	0	FALSE
Adipose	Dennd10	gene expression	Dennd10	0.03	5	0.04	8.4e-05	-5.34	9.14e-08	0.01	FALSE
Adipose	Emx2os	gene expression	Emx2os	0.13	1	0.1	2.9e-11	6	2.03e-09	0.18	TRUE
Adipose	Grk5	gene expression	Grk5	0.2	143	0.24	5.3e-26	-6.22	4.96e-10	0	FALSE
Adipose	Prdx3	gene expression	Prdx3	0.18	1	0.23	1.2e-24	5.62	1.92e-08	0	FALSE
Adipose	Sfxn4	gene expression	Sfxn4	0.03	1	0.03	2.0e-04	5.19	2.10e-07	0.03	FALSE
Adipose	Zfp950	gene expression	Zfp950	0.03	1	0.03	6.1e-04	-5.64	1.71e-08	0.03	FALSE
Adipose	Grk5	isoform ratio	XM_039088828.1	0.03	1	0.01	1.3e-02	5.53	3.22e-08	0.03	FALSE
Adipose	Emx2os	mRNA stability	Emx2os	0.14	1	0.11	5.1e-12	5.5	3.78e-08	0.01	FALSE
Adipose	Grk5	mRNA stability	Grk5	0.02	1	0.01	5.3e-02	-5.99	2.08e-09	0.03	FALSE
BLA	Grk5	alternative polyA	XM_039088801.1	0.06	1	0.03	1.2e-02	6.76	1.41e-11	0.04	FALSE
BLA	Ces2c	gene expression	Ces2c	0.24	1	0.16	8.0e-09	-5.54	3.06e-08	0.25	FALSE
BLA	Emx2os	gene expression	Emx2os	0.34	1	0.18	3.7e-10	5.83	5.59e-09	0.07	FALSE
BLA	Rab11fip2	gene expression	Rab11fip2	0.07	1	0.04	2.4e-03	5.67	1.46e-08	0.04	FALSE
BLA	Sfxn4	gene expression	Sfxn4	0.08	1	0.04	3.6e-03	-6.8	1.02e-11	0.06	FALSE
BLA	Emx2os	mRNA stability	Emx2os	0.13	2224	0.04	3.8e-03	-5.79	7.00e-09	0.15	FALSE
BLA	Grk5	mRNA stability	Grk5	0.05	1	0.01	1.3e-01	5.54	3.11e-08	0.04	FALSE
BLA	Rab11fip2	mRNA stability	Rab11fip2	0.07	3	0.03	8.0e-03	-6.69	2.26e-11	0.32	FALSE
Brain	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	6.0e-04	5.53	3.22e-08	0.03	FALSE
Brain	Grk5	alternative polyA	XM_039088820.1	0.03	1	0.04	1.1e-04	-5.33	9.59e-08	0.03	FALSE
Brain	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	8.1e-04	5.53	3.22e-08	0.03	FALSE
Brain	Grk5	alternative polyA	XM_039088820.1	0.03	1	0.04	1.1e-04	-5.33	9.59e-08	0.03	FALSE
Brain	Ces2c	gene expression	Ces2c	0.23	1	0.27	3.5e-25	-5.19	2.15e-07	0.05	FALSE
Brain	LOC102550729	gene expression	LOC102550729	0.05	1	0.06	4.1e-06	-5.37	8.08e-08	0.01	FALSE
Brain	Nanos1	gene expression	Nanos1	0.1	16	0.08	3.2e-08	-5.33	9.68e-08	0.33	TRUE
Brain	Rab11fip2	gene expression	Rab11fip2	0.1	16	0.06	1.2e-06	7.03	2.09e-12	0.96	FALSE
Brain	Cacul1	isoform ratio	NM_001014248.2	0.12	1786	0.09	8.4e-09	5.91	3.34e-09	0.71	FALSE
Brain	Grk5	isoform ratio	XM_039088828.1	0.03	8	0.04	1.6e-04	-5.89	3.77e-09	0.05	FALSE
Brain	Emx2os	mRNA stability	Emx2os	0.11	1	0.1	1.2e-09	5.9	3.64e-09	0.11	FALSE
Brain	Grk5	mRNA stability	Grk5	0.03	17	0.03	4.8e-04	6.66	2.74e-11	0.28	FALSE
IL	Ces2c	gene expression	Ces2c	0.37	1	0.29	1.1e-07	-5.19	2.15e-07	0.05	FALSE
IL	Sfxn4	gene expression	Sfxn4	0.19	13	0.09	3.1e-03	6.24	4.44e-10	0.12	TRUE
LHb	Ces2c	gene expression	Ces2c	0.25	584	0.17	9.1e-05	6.11	9.84e-10	0.71	FALSE
LHb	Rab11fip2	gene expression	Rab11fip2	0.23	1	0.12	8.4e-04	7	2.65e-12	0.14	TRUE
Liver	Nanos1	gene expression	Nanos1	0.08	1	0.05	1.1e-06	5.63	1.84e-08	0	FALSE
Liver	Ces2c	mRNA stability	Ces2c	0.02	1	0.02	2.3e-03	5.54	3.11e-08	0.03	FALSE
NAcc	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	2.1e-04	5.39	6.92e-08	0.03	FALSE
NAcc	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	5.5e-04	5.39	6.92e-08	0.03	FALSE
NAcc	Ces2c	gene expression	Ces2c	0.18	16	0.21	9.9e-24	-5.79	7.21e-09	0.13	FALSE
NAcc	Emx2os	gene expression	Emx2os	0.33	6	0.22	1.7e-24	-5.64	1.67e-08	0.16	FALSE
NAcc	LOC120100068	gene expression	LOC120100068	0.07	2115	0.02	7.8e-04	-6.04	1.51e-09	0.15	FALSE
NAcc	Prlhr	gene expression	Prlhr	0.17	76	0.12	1.1e-13	-6.94	3.86e-12	0.42	FALSE
NAcc	Sfxn4	gene expression	Sfxn4	0.05	1	0.06	3.4e-07	-6.94	4.00e-12	0.81	FALSE
NAcc	Zfp950	gene expression	Zfp950	0.07	22	0.08	3.7e-09	-7.31	2.63e-13	0.41	TRUE
NAcc	Cacul1	isoform ratio	NM_001014248.2	0.06	1	0.06	6.0e-07	-6.85	7.42e-12	0.69	FALSE
NAcc	Dennd10	mRNA stability	Dennd10	0.02	1619	0.02	8.7e-04	-5.55	2.89e-08	0.52	FALSE
NAcc	Emx2os	mRNA stability	Emx2os	0.07	1	0.03	3.1e-04	5.96	2.56e-09	0.06	FALSE
NAcc	Fam204a	mRNA stability	Fam204a	0.02	1	0.02	3.1e-03	-6.02	1.78e-09	0.03	TRUE
NAcc	Grk5	mRNA stability	Grk5	0.06	1449	0.05	6.2e-07	-6.96	3.44e-12	0.17	FALSE
OFC	Ces2c	gene expression	Ces2c	0.24	1	0.24	1.7e-06	-5.19	2.15e-07	0.05	FALSE
OFC	Rab11fip2	gene expression	Rab11fip2	0.26	2382	0.2	1.7e-05	-5.8	6.54e-09	0.12	FALSE
PL	Grk5	alternative polyA	XM_039088820.1	0.02	1	0.03	5.6e-04	-5.24	1.59e-07	0.03	FALSE
PL	Grk5	alternative polyA	XM_039088820.1	0.04	1	0.04	4.0e-05	-5.24	1.59e-07	0.03	FALSE
PL	Emx2os	gene expression	Emx2os	0.37	11	0.3	4.3e-33	-5.8	6.49e-09	0.16	FALSE
PL	Cacul1	isoform ratio	NM_001014248.2	0.03	1	0.02	1.2e-03	-6.69	2.25e-11	0.04	FALSE
PL	Cacul1	intron excision ratio	chr1_259677583_259686255	0.02	1	0.02	1.6e-03	-6.87	6.22e-12	0.05	FALSE
PL	Emx2os	mRNA stability	Emx2os	0.12	13	0.06	1.1e-06	-6.01	1.81e-09	0.17	FALSE
pVTA	Ces2c	gene expression	Ces2c	0.4	1	0.32	1.3e-14	-5.48	4.16e-08	0.2	FALSE
pVTA	Emx2os	gene expression	Emx2os	0.25	1	0.13	3.8e-06	5.43	5.48e-08	0.03	FALSE
pVTA	Prlhr	gene expression	Prlhr	0.09	1	0.07	5.1e-04	6.69	2.25e-11	0.05	FALSE
pVTA	Sfxn4	gene expression	Sfxn4	0.1	1405	0.08	1.8e-04	6.14	8.32e-10	0.39	FALSE
pVTA	Grk5	mRNA stability	Grk5	0.09	1	0.06	1.4e-03	5.77	7.74e-09	0.04	FALSE