Hub : Traits : Left kidney weight : ← →

chr1:78,023,219-79,954,878

Trait: Left kidney weight

Best TWAS P=1.147458e-07 · Best GWAS P=9.61787e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Clasrp	alternative polyA	ENSRNOT00000075144	0.06	0.03	enet	33	0.03	2.1e-04	4.7	-5.1	3.4e-07	-0.30	0.55	0.44	FALSE
2	Adipose	Fbxo46	alternative TSS	ENSRNOT00000012082	0.05	0.04	enet	68	0.04	3.9e-05	4.6	5.1	3.0e-07	0.93	0.57	0.42	FALSE
3	Adipose	Fbxo46	alternative TSS	ENSRNOT00000118710	0.04	0.03	enet	124	0.03	1.4e-04	4.6	-5.2	2.1e-07	-0.92	0.56	0.41	FALSE
4	Adipose	Ercc1	mRNA stability	ENSRNOG00000017839	0.03	0.01	enet	143	0.02	3.0e-03	4.5	5.2	2.5e-07	0.91	0.44	0.46	FALSE
5	Adipose	Klc3	mRNA stability	ENSRNOG00000018101	0.02	0.01	enet	357	0.01	9.8e-03	5.0	5.2	1.7e-07	0.78	0.31	0.41	FALSE
6	Brain	Ercc2	mRNA stability	ENSRNOG00000017753	0.16	0.07	lasso	11	0.09	1.8e-08	5.0	-5.3	1.2e-07	-0.88	0.36	0.64	FALSE
7	Liver	Vasp	alternative TSS	ENSRNOT00000022214	0.05	0.02	enet	101	0.03	6.0e-04	4.7	-5.2	1.7e-07	-0.95	0.47	0.51	FALSE
8	Liver	Vasp	alternative TSS	ENSRNOT00000088676	0.05	0.02	enet	109	0.03	8.1e-04	4.7	5.2	2.6e-07	0.97	0.47	0.51	FALSE
9	Liver	Eml2	isoform ratio	ENSRNOT00000078336	0.14	0.01	lasso	26	0.01	7.2e-03	4.6	5.1	2.7e-07	0.95	0.45	0.38	FALSE
10	NAcc	Snrpd2	gene expression	ENSRNOG00000015844	0.05	0.03	enet	86	0.03	2.8e-03	4.8	5.3	1.1e-07	0.95	0.51	0.42	TRUE
11	NAcc	Fbxo46	isoform ratio	ENSRNOT00000012082	0.06	0.04	enet	10	0.05	7.4e-05	4.7	5.3	1.4e-07	0.93	0.53	0.45	FALSE
12	NAcc	Dmwd	intron excision ratio	chr1:78734515:78735157	0.05	0.04	lasso	8	0.05	2.0e-04	5.1	-5.1	2.8e-07	-0.73	0.56	0.40	FALSE
13	NAcc	Dmpk	intron excision ratio	chr1:78734515:78735157	0.05	0.04	lasso	12	0.05	2.0e-04	5.1	-5.1	2.7e-07	-0.74	0.56	0.40	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.