Best TWAS P=2.341292e-07 · Best GWAS P=1.003811e-06 conditioned to 1
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Brain | NA | intron excision ratio | chr2:8168283:8168408 | 0.03 | 0.02 | enet | 3 | 0.03 | 0.0014 | -4.6 | 5.2 | 2.3e-07 | -0.94 | 0.36 | 0.47 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.