Hub : Traits : BMI without tail : ← : →

chr1:257,928,278-260,518,987

Trait: BMI without tail

Best TWAS P=1.64e-15 · Best GWAS P=1.45e-15 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Grk5	alternative polyA	XM_039088801.1	0.1	68	0.13	8.2e-14	7.01	2.43e-12	0.02	FALSE
Adipose	Grk5	alternative polyA	XM_039088820.1	0.07	1	0.09	1.5e-10	-6.78	1.24e-11	0.01	FALSE
Adipose	Grk5	alternative polyA	XM_039088801.1	0.11	1	0.13	1.5e-14	6.67	2.49e-11	0	FALSE
Adipose	Grk5	alternative polyA	XM_039088820.1	0.07	1	0.09	3.3e-10	-6.78	1.24e-11	0.01	FALSE
Adipose	Ces2c	gene expression	Ces2c	0.11	55	0.07	2.4e-08	-5.68	1.36e-08	0.33	FALSE
Adipose	Dennd10	gene expression	Dennd10	0.03	5	0.04	8.4e-05	-6.67	2.54e-11	0.03	FALSE
Adipose	Grk5	gene expression	Grk5	0.2	143	0.24	5.3e-26	-6.23	4.57e-10	0	TRUE
Adipose	LOC102550729	gene expression	LOC102550729	0.04	866	0.04	4.1e-05	5.81	6.22e-09	0.09	TRUE
Adipose	Prdx3	gene expression	Prdx3	0.18	1	0.23	1.2e-24	5.4	6.73e-08	0	FALSE
Adipose	Sfxn4	gene expression	Sfxn4	0.03	1	0.03	2.0e-04	7.06	1.63e-12	0.03	FALSE
Adipose	Zfp950	gene expression	Zfp950	0.03	1	0.03	6.1e-04	-5.36	8.10e-08	0.03	FALSE
Adipose	Grk5	isoform ratio	XM_039088828.1	0.03	1	0.01	1.3e-02	6.78	1.24e-11	0.03	FALSE
BLA	Grk5	alternative polyA	XM_039088801.1	0.06	1	0.03	1.2e-02	7.68	1.61e-14	0.04	FALSE
BLA	Ces2c	gene expression	Ces2c	0.24	1	0.16	8.0e-09	-6.8	1.06e-11	0.78	FALSE
BLA	Rab11fip2	gene expression	Rab11fip2	0.07	1	0.04	2.4e-03	5.66	1.47e-08	0.04	FALSE
BLA	Sfxn4	gene expression	Sfxn4	0.08	1	0.04	3.6e-03	-7.97	1.64e-15	0.34	TRUE
BLA	Emx2os	mRNA stability	Emx2os	0.13	2224	0.04	3.8e-03	-5.91	3.53e-09	0.22	FALSE
BLA	Grk5	mRNA stability	Grk5	0.05	1	0.01	1.3e-01	6.8	1.02e-11	0.04	FALSE
BLA	Rab11fip2	mRNA stability	Rab11fip2	0.07	3	0.03	8.0e-03	-7.09	1.37e-12	0.42	FALSE
Brain	Fam204a	alternative polyA	XM_039110388.1	0.03	1	0.04	2.4e-04	6.88	5.87e-12	0.03	FALSE
Brain	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	6.0e-04	6.78	1.24e-11	0.03	FALSE
Brain	Grk5	alternative polyA	XM_039088820.1	0.03	1	0.04	1.1e-04	-6.66	2.71e-11	0.03	FALSE
Brain	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	8.1e-04	6.78	1.24e-11	0.03	FALSE
Brain	Grk5	alternative polyA	XM_039088820.1	0.03	1	0.04	1.1e-04	-6.66	2.71e-11	0.03	FALSE
Brain	Ces2c	gene expression	Ces2c	0.23	1	0.27	3.5e-25	-6.82	8.85e-12	0.81	FALSE
Brain	LOC102550729	gene expression	LOC102550729	0.05	1	0.06	4.1e-06	-6.7	2.05e-11	0.04	FALSE
Brain	Nanos1	gene expression	Nanos1	0.1	16	0.08	3.2e-08	-6.78	1.18e-11	0.64	FALSE
Brain	Prlhr	gene expression	Prlhr	0.03	1911	0.01	1.4e-02	5.99	2.06e-09	0.41	FALSE
Brain	Rab11fip2	gene expression	Rab11fip2	0.1	16	0.06	1.2e-06	5.96	2.59e-09	0.2	FALSE
Brain	Sfxn4	gene expression	Sfxn4	0.08	1405	0.09	9.2e-09	5.6	2.09e-08	0.01	FALSE
Brain	Zfp950	gene expression	Zfp950	0.06	958	0.05	3.2e-05	5.2	2.02e-07	0.06	FALSE
Brain	Cacul1	isoform ratio	NM_001014248.2	0.12	1786	0.09	8.4e-09	7.36	1.81e-13	0.88	FALSE
Brain	Cacul1	isoform ratio	NM_001416001.1	0.09	1786	0.09	1.4e-08	-6.68	2.38e-11	0.83	FALSE
Brain	Grk5	isoform ratio	XM_039088828.1	0.03	8	0.04	1.6e-04	-6.67	2.48e-11	0.1	FALSE
Brain	Cacul1	intron excision ratio	chr1_259677583_259686255	0.12	83	0.11	1.9e-10	-7.19	6.34e-13	0.86	FALSE
Brain	Grk5	mRNA stability	Grk5	0.03	17	0.03	4.8e-04	5.89	3.78e-09	0.13	FALSE
IL	Ces2c	gene expression	Ces2c	0.37	1	0.29	1.1e-07	-6.82	8.85e-12	0.54	FALSE
IL	Sfxn4	gene expression	Sfxn4	0.19	13	0.09	3.1e-03	7.72	1.12e-14	0.17	FALSE
IL	Sfxn4	mRNA stability	Sfxn4	0.48	1	0.18	3.8e-05	-6.88	5.87e-12	0.05	FALSE
LHb	Ces2c	gene expression	Ces2c	0.25	584	0.17	9.1e-05	5.82	5.76e-09	0.51	FALSE
LHb	Rab11fip2	gene expression	Rab11fip2	0.23	1	0.12	8.4e-04	5.61	2.01e-08	0.05	TRUE
LHb	Grk5	mRNA stability	Grk5	0.28	1449	0.09	4.3e-03	-5.29	1.21e-07	0.09	FALSE
Liver	Nanos1	gene expression	Nanos1	0.08	1	0.05	1.1e-06	5.66	1.51e-08	0	FALSE
Liver	Cacul1	isoform ratio	NM_001014248.2	0.03	1784	0.02	6.6e-03	7.03	2.07e-12	0.4	FALSE
Liver	Ces2c	mRNA stability	Ces2c	0.02	1	0.02	2.3e-03	6.8	1.02e-11	0.06	FALSE
Liver	Grk5	mRNA stability	Grk5	0.03	41	0.01	3.2e-02	-6.68	2.34e-11	0.24	TRUE
NAcc	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	2.1e-04	6.74	1.54e-11	0.03	FALSE
NAcc	Grk5	alternative polyA	XM_039088801.1	0.02	1	0.03	5.5e-04	6.74	1.54e-11	0.03	FALSE
NAcc	Ces2c	gene expression	Ces2c	0.18	16	0.21	9.9e-24	-6.03	1.62e-09	0.75	FALSE
NAcc	Prlhr	gene expression	Prlhr	0.17	76	0.12	1.1e-13	-7.51	5.95e-14	0.7	TRUE
NAcc	Rab11fip2	gene expression	Rab11fip2	0.03	20	0.03	1.3e-04	6.16	7.13e-10	0.36	TRUE
NAcc	Sfxn4	gene expression	Sfxn4	0.05	1	0.06	3.4e-07	-7.5	6.36e-14	0.46	FALSE
NAcc	Zfp950	gene expression	Zfp950	0.07	22	0.08	3.7e-09	-7.13	9.71e-13	0.52	FALSE
NAcc	Cacul1	isoform ratio	NM_001014248.2	0.06	1	0.06	6.0e-07	-7.96	1.79e-15	0.97	FALSE
NAcc	Cacul1	isoform ratio	NM_001416001.1	0.04	1786	0.04	2.4e-05	-6.83	8.72e-12	0.69	FALSE
NAcc	Dennd10	mRNA stability	Dennd10	0.02	1619	0.02	8.7e-04	-7.49	6.75e-14	0.74	FALSE
NAcc	Fam204a	mRNA stability	Fam204a	0.02	1	0.02	3.1e-03	-7.26	3.84e-13	0.03	FALSE
NAcc	Grk5	mRNA stability	Grk5	0.06	1449	0.05	6.2e-07	-6.44	1.18e-10	0.03	FALSE
OFC	Ces2c	gene expression	Ces2c	0.24	1	0.24	1.7e-06	-6.82	8.85e-12	0.33	FALSE
OFC	Rab11fip2	gene expression	Rab11fip2	0.26	2382	0.2	1.7e-05	-6.56	5.50e-11	0.38	FALSE
OFC	Rab11fip2	mRNA stability	Rab11fip2	0.22	2382	0.17	8.8e-05	-5.18	2.27e-07	0.4	FALSE
PL	Grk5	alternative polyA	XM_039088801.1	0.03	1449	0.02	4.0e-03	-5.87	4.48e-09	0.08	FALSE
PL	Grk5	alternative polyA	XM_039088820.1	0.02	1	0.03	5.6e-04	-6.86	6.98e-12	0.03	FALSE
PL	Grk5	alternative polyA	XM_039088801.1	0.04	1449	0.02	3.7e-03	-5.41	6.26e-08	0.05	FALSE
PL	Grk5	alternative polyA	XM_039088820.1	0.04	1	0.04	4.0e-05	-6.86	6.98e-12	0.03	FALSE
PL	Ces2c	gene expression	Ces2c	0.41	82	0.37	8.2e-43	-6.18	6.27e-10	0.68	FALSE
PL	Sfxn4	gene expression	Sfxn4	0.14	1405	0.12	4.8e-13	7.07	1.50e-12	0.06	TRUE
PL	Zfp950	gene expression	Zfp950	0.04	958	0.03	3.5e-04	5.97	2.41e-09	0.08	FALSE
PL	Cacul1	isoform ratio	NM_001014248.2	0.03	1	0.02	1.2e-03	-7.66	1.91e-14	0.09	FALSE
PL	Cacul1	intron excision ratio	chr1_259677583_259686255	0.02	1	0.02	1.6e-03	-7.96	1.65e-15	0.19	FALSE
pVTA	Ces2c	gene expression	Ces2c	0.4	1	0.32	1.3e-14	-6.81	9.47e-12	0.8	FALSE
pVTA	Prlhr	gene expression	Prlhr	0.09	1	0.07	5.1e-04	7.66	1.91e-14	0.06	TRUE
pVTA	Sfxn4	gene expression	Sfxn4	0.1	1405	0.08	1.8e-04	7.77	7.96e-15	0.56	FALSE
pVTA	Grk5	mRNA stability	Grk5	0.09	1	0.06	1.4e-03	5.35	8.65e-08	0.04	FALSE